Resolvin D3
Resolvin D3 (RvD3) is a docosahexaenoic acid (DHA) derived mediator. Resolvin D3 is dysregulated in arthritis and reduces arthritic inflammation.
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- No. CAS: 916888-47-6
- Fòrmula: C22H32O5
- Peso molecular:376.49
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Almacenamiento:
Solution, -20°C, 2 years
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Actividad biológica
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Chemical Information
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Help & FAQs
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7(S)-Maresin 1Maresin 1 Exomer -
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17(R)-Resolvin D4Resolvin D4 R-enantiomer -
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Maresin Conjugates in Tissue Regeneration 2Specialized Pro-resolving Mediator
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Actividad biológica
Descripciòn
In Vitro
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male C57Bl/6 mice (12 weeks old) or ALX/fpr2/3 KO mice[1]
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Dosage:100 ng/100 µl
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Administration:IP; daily for 6 days
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Result:Alleviated arthritis progression, reduced edema and limited leukocyte numbers in murine K/BxN-serum induced arthritis.
Chemical Information
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No. CAS 916888-47-6
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Appearance Liquid
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Peso molecular 376.49
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Fòrmula C22H32O5
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Color Colorless to light yellow
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SMILES
CC/C=C\C[C@H](O)/C=C/C=C\C[C@@H](O)/C=C/C=C/C=C\[C@@H](O)CCC(O)=O
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Synonyms
RvD3
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Solution, -20°C, 2 years
Pureza y Documentación
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Ficha de datos (262 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
Referencias
[1]. Hildur H Arnardottir, et al. Resolvin D3 Is Dysregulated in Arthritis and Reduces Arthritic Inflammation. J Immunol. 2016 Sep 15;197(6):2362-8. [Content Brief]
[2]. Jennifer K Colby, et al. Resolvin D3 and Aspirin-Triggered Resolvin D3 Are Protective for Injured Epithelia. Am J Pathol. 2016 Jul;186(7):1801-1813. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Resolvin D3 Related Classifications
HY-136540 Related Classifications
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