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Resolvin D3 (Synonyms: RvD3)

Cat. No.: HY-136540
Handling Instructions

Resolvin D3 (RvD3) is a docosahexaenoic acid (DHA) derived mediator. Resolvin D3 is dysregulated in arthritis and reduces arthritic inflammation.

For research use only. We do not sell to patients.

Resolvin D3 Chemical Structure

Resolvin D3 Chemical Structure

CAS No. : 916888-47-6

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25 μg (265.6 µM * 250 μL in Ethanol) USD 880 Ask For Quote & Lead Time

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Description

Resolvin D3 (RvD3) is a docosahexaenoic acid (DHA) derived mediator. Resolvin D3 is dysregulated in arthritis and reduces arthritic inflammation[1][2].

In Vitro

RvD3 (RvD3; 10 nM) significantly inhibits tumor necrosis factor-α–induced NF-κB activation in A549 epithelial cells[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Resolvin D3 (RvD3; 100 ng/100 µl; IP; daily for 6 days) alleviates arthritis progression, reduces edema and limits leukocyte numbers in murine K/BxN-serum induced arthritis[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male C57Bl/6 mice (12 weeks old) or ALX/fpr2/3 KO mice[1]
Dosage: 100 ng/100 µl
Administration: IP; daily for 6 days
Result: Alleviated arthritis progression, reduced edema and limited leukocyte numbers in murine K/BxN-serum induced arthritis.
Molecular Weight

376.49

Formula

C₂₂H₃₂O₅

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Solution, -20°C, 2 years

References

Purity: ≥95.0%

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Resolvin D3
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