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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
ation
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "ation" in MCE Product Catalog:
21
4
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Anthocyans other families Flavonoids Anti-aging Phenols Polyphenols Plants Disease Research Fields Cancer
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1 Cited Publications
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ATIC-IN-1 (compound 14) acetate is an inhibitor targeting to Aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC) dimerization with a Ki value of 685 nM, whcich catalyzes de novo purine biosynthesis. ATIC dimerization is crucial for its aminoimidazole carboxamide ribonucleotide (AICAR) transformylase activity. ATIC-IN-1 acetate exhibits anti-tumor activity via reduction in cell numbers and cell division rates .
Cat. No.: HY-W011927
CAS No.: 80-09-1
Synonyms: Bisphenol S; Bis(4-hydroxyphenyl) sulfone
Synonyms: 5-Formamidoimidazole-4-carboxamide ribotide
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Cat. No.: HY-N1448
CAS No.: 22007-72-3
Category:
Infection Flavonols Flavonoids Phenols Polyphenols Erythrina stricta Roxb. Plants Compositae Disease Research Fields
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Cat. No.: HY-N0499A
CAS No.: 13306-05-3
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Cat. No.: HY-P990067
CAS No.: 2639688-77-8
Synonyms: ATOR-1017
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Cat. No.: HY-29244
CAS No.: 67095-44-7
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ATIC-IN-2 (Compound 1) is a competitive inhibitor for the bifunctional enzyme AICAR Tfase/IMPCH (ATIC), that binds to inosine monophosphate cyclohydrolase (IMPCH) with a Ki of 0.13 μM .
Cat. No.: HY-150252
CAS No.: 1402453-15-9
ATIC-IN-1(compound 14) is an inhibitor targeting to Aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC) dimerization with a Ki value of 685 nM. ATIC dimerization is crucial for its aminoimidazole carboxamide ribonucleotide (AICAR) transformylase activity. ATIC-IN-1 exhibits anti-tumor activity via reduction in cell numbers and cell division rates .
Cat. No.: HY-RS01156
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ATIC Human Pre-designed siRNA Set A contains three designed siRNAs for ATIC gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-178468
CAS No.: 3053592-61-0
PARP1-IN-47 (Compound 35) is a highly selective PARP1 inhibitor (IC50 <100 nM). PARP1-IN-47 blocks poly(ADP-ribosyl)ation and disrupts DNA damage repair pathways to induce tumor cell apoptosis. PARP1-IN-47 is promising for research of solid tumors and hematological malignancies .
Cat. No.: HY-RS23569
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Atic Rat Pre-designed siRNA Set A contains three designed siRNAs for Atic gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS01126
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ATE1 Human Pre-designed siRNA Set A contains three designed siRNAs for ATE1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-N1448R
CAS No.: 22007-72-3
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Cat. No.: HY-141324
CAS No.: 720707-93-7
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Tetraethyl butane-1,4-diylbis(phosphoramidate) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
Cat. No.: HY-135238
CAS No.: 111728-01-9
Synonyms: PD-117302
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(rel)-RSD 921 (PD-117302) is a κ-opioid receptor agonist. (rel)-RSD 921 did not have a greater food-inducing effect in obese than in lean Zucker rats; in both obese and lean Zucker rats, lean rats were more sensitive to its initial food-inducing effect but ultimately ate less.
Cat. No.: HY-RS17124
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Atic Mouse Pre-designed siRNA Set A contains three designed siRNAs for Atic gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-136263
CAS No.: 146385-37-7
Biotin-NAD + is a PARylation donor and also a substrate of poly (ADP-ribose) polymerase-1 (PARP1). Under the mediation of PARP1, Biotin-NAD + undergoes poly (ADP-ribosyl) ation to generate biotinylated poly (ADP-ribose) polymers. Biotin-NAD + can be used for pull-down assays of PARylated proteins in renal epithelial cells. Biotin-NAD + is applicable to cancer-related research .
Cat. No.: HY-N17727
CAS No.: 331433-08-0
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
