3067165-96-9

ATIC-IN-1 acetate Chemical Structure
3067165-96-9

Chemical Structure

ATIC-IN-1 acetate

  • CAS No.: 3067165-96-9
  • Formula:C23H37N7O7
  • Molecular Weight:523.58

IUPAC Name: (S)-2-acetamido-N-((S)-1-(diethylamino)-3-(4-nitrophenyl)-1-oxopropan-2-yl)-5-guanidinopentanamide acetate

InChIKey: DJZJDKMNBAGSBX-APTPAJQOSA-N

SMILES: N=C(N)NCCC[C@H](NC(C)=O)C(N[C@H](C(N(CC)CC)=O)CC1=CC=C(C=C1)[N+]([O-])=O)=O.CC(O)=O

Biological Activity: ATIC-IN-1 (compound 14) acetate is an inhibitor targeting to Aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC) dimerization with a Ki value of 685 nM, whcich catalyzes de novo purine biosynthesis. ATIC dimerization is crucial for its aminoimidazole carboxamide ribonucleotide (AICAR) transformylase activity. ATIC-IN-1 acetate exhibits anti-tumor activity via reduction in cell numbers and cell division rates[1].

Cat. No. Product Name Purity Description Pricing
HY-150252A 		ATIC-IN-1 acetate 99.96% ATIC-IN-1 (compound 14) acetate is an inhibitor targeting to Aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC) dimerization with a Ki value of 685 nM, whcich catalyzes de novo purine biosynthesis. ATIC dimerization is crucial for its aminoimidazole carboxamide ribonucleotide (AICAR) transformylase activity. ATIC-IN-1 acetate exhibits anti-tumor activity via reduction in cell numbers and cell division rates.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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Structural Analogs

References

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