PARP1-IN-47
PARP1-IN-47 (Compound 35) is a highly selective PARP1 inhibitor (IC50 <100 nM). PARP1-IN-47 blocks poly(ADP-ribosyl)ation and disrupts DNA damage repair pathways to induce tumor cell apoptosis. PARP1-IN-47 is promising for research of solid tumors and hematological malignancies.
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- CAS. Nr.: 3053592-61-0
- Formel: C21H24F3N7O2
- Molecular Weight:463.46
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
IC50 & Target
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PARP1 <100 nM (IC50) |
Chemical Information
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CAS. Nr. 3053592-61-0
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Molecular Weight 463.46
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Formel C21H24F3N7O2
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SMILES
O=C(N1)C(CC)=CN2C1=CC(CN3CCN(CC3)C4=C(C(F)(F)F)N=C(C(NC)=O)C=C4)=N2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)