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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
bacterial cytoplasmic membrane potential
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "bacterial cytoplasmic membrane potential" in MCE Product Catalog:
1
Target:
Research Areas:
Telavancin hydrochloride (TD-6424 hydrochloride) is a bactericidal agent that exhibits inhibitory activity against Staphylococcus aureus. Telavancin hydrochloride inhibits bacterial cell wall synthesis by binding to the lipid-linked N-acetylglucosamine-N-muramyl pentapeptide (with a D-Ala-D-Ala terminus), a peptidoglycan precursor, and blocks the transglycosylation and transpeptidation steps. Telavancin hydrochloride disrupts bacterial membrane barrier function, induces dissipation of bacterial membrane potential, and causes leakage of cytoplasmic ATP and potassium ions, with its activity restricted exclusively to bacterial membranes. Telavancin hydrochloride can be used in research on bacterial infections, central venous catheter-related bloodstream infections, and Gram-positive bacterial pneumonia .
Cat. No.: HY-N125722
CAS No.: 33538-71-5
Synonyms: Aabomycin A1
Cat. No.: HY-170991
Research Areas:
C12-rrw-NH2 (Compound Lip7) is an antibacterial agent against gram-positive bacteria, especially against Methicillin (HY-121544)-resistant Staphylococcus aureus (MRSA). C12-rrw-NH2 induces bacterial death via depolarizing the bacterial cytoplasmic membrane, disrupting the integrity of the bacterial membrane, leading to leakage of nucleic acid and protein and promoting the generation of Reactive Oxygen Species. C12-rrw-NH2 is potential to be used for research of developing high-stability antimicrobial peptides .
Cat. No.: HY-P10134
CAS No.: 335080-41-6
Salivaricin B is a broad-spectrum bacteriocin produced by Lactobacillus M7. Salivaricin B reduces cell wall thickness, induces abnormal septum formation, and exerts rapid bactericidal activity against susceptible Gram-positive bacteria without disrupting cytoplasmic membrane integrity or dissipating membrane potential. Salivaricin B inhibits the growth of oral, upper respiratory tract and food-related Gram-positive pathogens, spoilage bacteria, lactobacilli, and SboB-non-producing Streptococcus salivarius strains. Its activity is strain-dependent, and it has no effect on Gram-negative bacteria. Salivaricin B can be used in studies related to bacterial infections .
Cat. No.: HY-W012880
CAS No.: 6920-22-5
Synonyms: Hexane-1,2-diol
Target:
Research Areas:
1,2-Hexanediol (Hexane-1,2-diol) is a broad-spectrum antibacterial agent. 1,2-Hexanediol exhibits bactericidal activity against Gram-positive and Gram-negative bacteria, as well as antifungal activity against fungal organisms. 1,2-Hexanediol disrupts the cytoplasmic membrane potential of bacteria. 1,2-Hexanediol can be used in research on bacterial and fungal infections, as well as cosmetic preservation .
Cat. No.: HY-P11615
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
