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586

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30

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4

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Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0116
    Hematoxylin
    10+ Cited Publications

    Natural black 1; Haematoxylin

    Amyloid-β Others
    Hematoxylin (Natural Black 1), a naturally occurring flavonoid compound derived from Caesalpinia sappan Linn.. Hematoxylin is a nuclear stain in histology and is also a potent Aβ42 fibrillogenesis inhibitor with an IC50 of 1.6 μM.
    Hematoxylin
  • HY-D0213
    Sudan Black B
    1 Publications Verification

    Environmental Pollutants Fluorescent Dye Others
    Sudan Black B, a fat-soluble diazo dye, is a histochemical stain. Sudan Black B can be used for staining of neutral triglycerides and lipids .
    Sudan Black B
  • HY-N6949
    Juglone
    4 Publications Verification

    5-Hydroxy-1,4-naphthalenedione

    Bacterial NF-κB Toll-like Receptor (TLR) Apoptosis Infection Inflammation/Immunology Cancer
    Juglone (5-hydroxy-1,4-naphthalenedione) is a yellow dye that can be extracted from Juglans regia. Juglone induces apoptosis through the mitochondrial pathway. Juglone has antibacterial and antitumor activity .
    Juglone
  • HY-Y0695

    Naphthol Blue black

    Environmental Pollutants Fluorescent Dye Others
    Amido Black 10B (Naphthol Blue Black) is a highly toxic azo dye. Amido Black 10B is genotoxic and mutagenic. Amido Black 10B can cause respiratory problems. Amido Black 10B is used for amino acid dyeing .
    Amido Black 10B
  • HY-Y0351
    Phenylthiourea
    3 Publications Verification

    Phenylthiocarbamide

    Tyrosinase Endogenous Metabolite Others
    Phenylthiourea (Phenylthiocarbamide) is an inhibitor for phenoloxidase. Phenylthiourea inhibits enzymatic oxidation of DOPA by phenoloxidase (Ki = 0.21 μM). Phenylthiourea is an effective inhibitor for tyrosinase. Phenylthiourea can lead to graying of hair in black rats due to the interference with melanin formation .
    Phenylthiourea
  • HY-D0256
    Direct Black 38
    2 Publications Verification

    Chlorazol black E; Ferristatin II disodium; C.I. 30235

    Biochemical Assay Reagents Others
    Direct Black 38 (Chlorazol Black E) is a benzidine-based azo dye, a substrate of Enterococcus gallinarum, and is mainly used for textile dyeing. Direct Black 38 is biodegradable after being reduced by microbial enzymes (such as Enterococcus gallinarum azoreductase), breaking the azo bonds and releasing benzidine and 4-aminobiphenyl. Direct Black 38 can be used in environmental toxicology, wastewater treatment and carcinogenicity studies, but its metabolite benzidine is listed as a human carcinogen .
    Direct Black 38
  • HY-W041301

    Drug Isomer Inflammation/Immunology
    (±)-Dihydroactinidiolide is the dextrorotatory form of Dihydroactinidiolide (HY-107805). (±)-Dihydroactinidiolide has a strong, pleasant musky, tea-like and tobacco-like aroma and is mainly found in black tea, tobacco and fruits. (±)-Dihydroactinidiolide has antioxidant activity and can be derived from β-carotene.or light adaptation in Arabidopsis .
    (±)-Dihydroactinidiolide
  • HY-Y1426

    o-Hydroxyacetophenone; o-Acetylphenol

    Drug Intermediate Others
    2'-Hydroxyacetophenone is found in alcoholic beverages. 2'-Hydroxyacetophenone is present in tomato, cassia, fried beef, rum, whiskey, cocoa, coffee and black tea. 2'-Hydroxyacetophenone is a flavouring ingredient. Building block in chemical synthesis.
    2'-Hydroxyacetophenone
  • HY-W110910

    Biochemical Assay Reagents Infection
    Eriochrome black T, Indicator is a complexing agent for metal ions (e.g., Ca 2+, Mg 2+) and is used as an indicator in complexometric titrations. Eriochrome black T, Indicator forms colored complexes with metal ions through covalent coordination bonds, and indicates the endpoint of the titration by color change. Eriochrome black T, Indicator can be used as an anionic azo dye in photocatalytic degradation studies to evaluate the performance of photocatalysts. The reaction solution of Eriochrome black T, Indicator combined with Mg 2+ is initially purple. During loop-mediated isothermal amplification (LAMP), the color changes from purple to sky blue due to the consumption of Mg 2+ by the formation of magnesium pyrophosphate, indicating a positive reaction. The optimal concentration of Eriochrome black T, Indicator in LAMP is 60 μM, and the detection limit for Mycobacterium tuberculosis is 1 pg DNA/reaction .
    Eriochrome black T, Indicator
  • HY-128382

    E 151

    Enterovirus Infection
    Brilliant black BN (E151) is an azo dye and a food colorant . Brilliant black BN is a promising antiviral agent against EV71 infection via inhibiting the interaction between EV71 and its cellular uncoating factor cyclophilin A. Brilliant black BN has the potential for the investigation of contagious disease .
    Brilliant Black BN
  • HY-149874
    BMS-502
    1 Publications Verification

    DGK Inflammation/Immunology Cancer
    BMS-502 (Compound 22) is a potent dual inhibitor of diacylglycerol kinase (DGK) α and ζ with IC50 of 4.6 nM and 2.1 nM. BMS-502 enhanced T cell immune responses in mice. BMS-502 can be used in tumor immunity related research .
    BMS-502
  • HY-23155
    2-Phenylethyl isothiocyanate
    1 Publications Verification

    2-PE ITC

    Fungal Infection
    2-Phenylethyl isothiocyanate is a potent antifungal agent. 2-Phenylethyl isothiocyanate significantly inhibited spore germination and mycelial growth of Alternaria alternata, with a MIC (minimum inhibitory concentration) of 1.22 mM. The antifungal effect of 2-Phenylethyl isothiocyanate against Alternaria alternate might be via reduction in toxin content and breakdown of cell membrane integrity .
    2-Phenylethyl isothiocyanate
  • HY-N2322
    Khasianine
    3 Publications Verification

    Others Cancer
    Khasianine is a steroidal glycoalkaloid which is obtained from black nightshade (Solanum Nigrum L.), which displays antitumor activity.
    Khasianine
  • HY-137345

    PROTACs Toll-like Receptor (TLR) Cancer
    DB-3-291 is potent and selective PROTAC CSK degrader, with a Kd of 1 nM (Pink: CSK ligand (HY-131669); Blue: E3 ligase ligand (HY-103597); Black: linker (HY-N2407)) .
    DB-3-291
  • HY-W250145

    Nigrosine

    Biochemical Assay Reagents Others
    Acid Black 2 (Nigrosine) is an alcohol-soluble absorber used to mimic skin pigmentation in tissue-mimicking phantoms. Acid Black 2 acts as an absorber in silicone-based thin tissue phantoms to simulate varying melanosome volume fractions in skin .
    Acid Black 2
  • HY-139161

    Environmental Pollutants Fungal Infection
    Penflufen is a highly efficient, broad-spectrum succinate dehydrogenase inhibitor (SDHI). Penflufen can be used as a fungicide and has broad bioactivity against many fungal diseases, including potato black scurf, wheat sharp eyespot, rice sheath blight, and root rot in peanut and other similar fungal diseases .
    Penflufen
  • HY-153880

    LYTACs Ras Cancer
    KRAS degrader-1 is a potent KRAS degrader. KRAS degrader-1 targets specific proteins for degradation via the autophagy-lysosomal degradation pathway. KRAS degrader-1 is suitable for use in cancer research. (Blue: KRAS G12C-IN-72 (HY-128414); Black: Linker (HY-175587); Pink: 5-Iodoindolin-2-one (HY-76986); Blue + Black: KRAS ligand-Linker Conjugate 7 (HY-175586)) .
    KRAS degrader-1
  • HY-176184

    PROTACs Discoidin Domain Receptor Cancer
    PROTAC DDR1 degrader-1 is a PROTAC based DDR1 degrader (Red: DDR1 inhibitor (HY-176185), black: linker, Blue: E3 ligase ligand) .
    PROTAC DDR1 degrader-1
  • HY-168221

    PROTACs Cancer
    YD54 is a PROTAC based SMARCA2 degrader with a DC50 of 3.5 nM (Red: SMARCA2 degrader (HY-44012B), black: linker, Blue: E3 ligase ligand) .
    YD54
  • HY-155361

    PROTACs Epigenetic Reader Domain Cancer
    PROTAC BRD9 Degrader-7 is an orally active, selective BRD9 PROTAC degrader (DC50 = 1.02 nM). PROTAC BRD9 Degrader-7 mediates BRD9 degradation via the ubiquitin-proteasome system. PROTAC BRD9 Degrader-7 exhibits proliferation inhibitory activity in the MV4-11 cells. PROTAC BRD9 Degrader-7 can be used in the research of acute myeloid leukemia and other related malignancies. (Pink: BI 7271: HY-123616, Blue: 5-Aminothalidomide: HY-W023573, Blue + Black: Thalidomide-5-piperazine: HY-W834174, Black: N,N'-Dimethylpiperazine: HY-W539783) .
    PROTAC BRD9 Degrader-7
  • HY-W250148

    Spirit nigrosine

    Biochemical Assay Reagents Others
    Solvent black 5 (Spirit nigrosine) is a synthetic dye belonging to the family of azo dyes. Also known as oil black or naphthol black, it is dark blue-black and has excellent solubility in organic solvents. Solvent black 5 is commonly used as a colorant in various industrial applications such as printing inks, coatings and plastics. It can also be used as an indicator dye to detect the presence of metals in solution. Furthermore, due to its high absorption and emission properties in the near-infrared region, it has been used in scientific research as a fluorescent biomarker for tissues and cells. However, Solvent black 5 has been reported to have potentially toxic effects on human health and the environment and its use is therefore regulated in some countries.
    Solvent black 5
  • HY-W783421

    Reactive black 5

    Biochemical Assay Reagents Others
    C.I.Reactive Black 5 (Technical Grade) is a biological molecule.
    FXIIIa-IN-1 sodium
  • HY-D0741

    Fluorescent Dye Others
    Pigment black 32 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
    Pigment black 32
  • HY-N7664

    Others Others
    Isotheaflavin is one of antioxidant polyphenols in black tea .
    Isotheaflavin
  • HY-117451

    Bacterial Infection
    Dodine is a fungicide with plant disease suppressive activity. Dodine is used to control black spot on apples, pears and pecans, brown rot on peaches, and a variety of foliar diseases of peaches, strawberries, cherries, jacaranda and black walnuts. Dodine is also used as an industrial biocide and preservative .
    Dodine
  • HY-N10346A

    3-Butenyl glucosinolate

    Lipase Bacterial Infection Cancer
    Gluconapin (3-Butenyl glucosinolate) is an orally active aliphatic glucosinolate and also a flavor modifier. Gluconapin inhibits the elevation of plasma triglyceride levels in mice. Gluconapin also exhibits certain antibacterial activity .
    Gluconapin
  • HY-P3095

    Endogenous Metabolite Neurological Disease
    α-Latrotoxin, a potent neurotoxin from black widow spider venom, triggers synaptic vesicle exocytosis from presynaptic nerve terminals .
    α-Latrotoxin
  • HY-148276

    PROTACs IRAK Cancer
    KTX-497 is an IRAK4 PROTAC degrader with a DC50 value of 3 nM. KTX-497 can be used for the research of oncology .(Pink:IRAK4 inhibitor (HY-150735); Black: linker; Blue: CRBN Ligand (HY-10984))
    KTX-497
  • HY-D1492

    Fluorescent Dye Others
    Fast Sulphon Black F is a specific copper indicator. Fast Sulphon Black F can be used for EDTA titration .
    Fast Sulphon Black F
  • HY-D0277

    Fluorescent Dye
    Eriochrome black T is a complex indicator used in complex titrations, e.g.
    Eriochrome black T
  • HY-204591

    Drug Derivative Others
    Black pepper oleoresin is a substance extracted from the pepper plant (Piper nigrum), which has aroma, spiciness, and bioactive components. It is widely used in food, health products, cosmetics, and daily chemical products.
    Black pepper oleoresin
  • HY-170413

    PROTACs Btk Cancer
    PROTAC BTK Degrader-12 (EXAMPLE 19) is a PROTAC-based BTK degrader (Pink & black: BTK ligand & linker (HY-170414); Black: linker (HY-30105); Blue: CRBN ligand ( HY-W245311)) .
    PROTAC BTK Degrader-12
  • HY-B0887B

    (-)-trans-NRDC-143; (1S)-trans-Permethrin

    Insecticide Others
    (-)-trans-Permethrin ((-)-trans-NRDC-143) is a pyrethroid that can provide a satisfactory level of protection from black flies for cattle .
    (-)-trans-Permethrin
  • HY-D1121

    Fluorescent Dye
    Acid black 24 is a black agent whose staining effect is effectively removed by nanoscale zero-valent iron (NZVI) particles. The maximum unit removal capacity is 609.4 mg of dye per gram of NZVI.
    Acid black 24
  • HY-D0330

    Sunchromine blue black R

    Biochemical Assay Reagents Others
    Mordant black 17 (Sunchromine blue black R) is a versatile chelating agent, demonstrating significant adsorptive properties through its interaction with metal ions, enhancing the efficiency of polymeric materials in various applications.
    Mordant black 17
  • HY-D0605

    Fluorescent Dye
    Solvent Black 46 is a black dye. Its series of products, such as Solvent orange 60 (HY-D1177), has been used in dyeing applications of plastic materials.
    Solvent Black 46
  • HY-D0774

    Fluorescent Dye
    Direct Black 168 is a good dyeing agent for cotton fabrics.
    Direct Black 168
  • HY-D0524

    Fluorescent Dye
    Disperse black 9 is a violet dye commonly used for fiber dyeing.
    Disperse black 9
  • HY-N13217

    Others Others
    Black Cohosh Extract is the extract of Black Cohosh, with content of 2.5% , 5% Triterpenoid saponins.
    Black Cohosh Extract
  • HY-D0465

    Fluorescent Dye
    C.I. Direct black 80 is a good dyeing agent for cotton fabrics.
    C.I. Direct black 80
  • HY-D0256A

    Chlorazol black E free acid; Ferristatin II; C.I. 30235 free acid

    Biochemical Assay Reagents Others
    Direct Black 38 (Chlorazol Black E; Ferristatin II disodium) free acid is a benzidine-based azo dye, a substrate of Enterococcus gallinarum, and is mainly used for textile dyeing. Direct Black 38 free acid is biodegradable after being reduced by microbial enzymes (such as Enterococcus gallinarum azoreductase), breaking the azo bonds and releasing benzidine and 4-aminobiphenyl. Direct Black 38 free acid can be used in environmental toxicology, wastewater treatment and carcinogenicity studies, but its metabolite benzidine is listed as a human carcinogen .
    Direct Black 38 free acid
  • HY-D0634

    Fluorescent Dye Others
    Reactive Black 39 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
    Reactive Black 39
  • HY-N6949R

    5-Hydroxy-1,4-naphthalenedione (Standard)

    Reference Standards Bacterial NF-κB Toll-like Receptor (TLR) Apoptosis Infection Inflammation/Immunology Cancer
    Juglone (Standard) is the analytical standard of Juglone. This product is intended for research and analytical applications. Juglone (5-hydroxy-1,4-naphthalenedione) is a yellow dye that can be extracted from Juglans regia. Juglone induces apoptosis through the mitochondrial pathway. Juglone has antibacterial and antitumor activity .
    Juglone (Standard)
  • HY-N12272

    Acetyl-soyasaponin A2

    Others Others
    Soyasaponin Af (Acetyl-soyasaponin A2) is a saponin isolated from Black bean (Phaseolus vulgaris L.) seed coats .
    Soyasaponin Af
  • HY-23155R

    2-PE ITC (Standard)

    Fungal Reference Standards Infection
    2-Phenylethyl isothiocyanate (Standard) is the analytical standard of 2-Phenylethyl isothiocyanate. This product is intended for research and analytical applications. 2-Phenylethyl isothiocyanate is a potent antifungal agent. 2-Phenylethyl isothiocyanate significantly inhibited spore germination and mycelial growth of Alternaria alternata, with a MIC (minimum inhibitory concentration) of 1.22 mM. The antifungal effect of 2-Phenylethyl isothiocyanate against Alternaria alternate might be via reduction in toxin content and breakdown of cell membrane integrity .
    2-Phenylethyl isothiocyanate (Standard)
  • HY-156746

    PROTACs Btk Cancer
    DBt-10 is a potent BTK PROTAC degrader (DC50: 137 nM). Blue: DCAF1 binder (HY-149934); Black: linker; Pink: BTK ligand .
    DBt-10
  • HY-156745

    PROTACs Btk Cancer
    DDa-1 is a potent BTK degrader (DC50: 90 nM). Blue: DCAF1 binder (HY-149934), Black: linker, Pink: BTK ligand (HY-107447) .
    DDa-1
  • HY-158047

    PROTACs STING Infection
    UNC8900 is a VHL recruiting STING PROTAC degrader (DC50: 0.0.924 μM). UNC8900 can be used for research of viral or bacterial infection. (Blue: VHL ligand, black: linker; Pink: STING inhibitor) .
    UNC8900
  • HY-158046

    PROTACs STING Infection
    UNC8899 is a VHL-recruiting STING PROTAC degrader (DC50: 0.0.924 μM). UNC8899 can be used for viral or bacterial infection research (Blue: VHL ligand, Black: linker; Pink: STING inhibitor) .
    UNC8899
  • HY-173467

    PROTACs c-Myc Cancer
    PROTAC MTP3 degrade-1 is a PROTAC based MYC degrader (Red: MYC inhibitor (HY-173469), black: linker (HY-W008296), Blue: E3 ligase ligand (HY-14658)) .
    PROTAC MTP3 degrader-1

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