103-85-5
103-85-5
Chemical Structure
Phenylthiourea
Synonym(s): Phenylthiocarbamide
- CAS. Nr.: 103-85-5
- Formula:C7H8N2S
- Molecular Weight:152.22
IUPAC Name: 1-phenylthiourea
InChIKey: FULZLIGZKMKICU-UHFFFAOYSA-N
SMILES: S=C(NC1=CC=CC=C1)N
Biological Activity: Phenylthiourea (Phenylthiocarbamide) is an inhibitor for phenoloxidase. Phenylthiourea inhibits enzymatic oxidation of DOPA by phenoloxidase (Ki = 0.21 μM). Phenylthiourea is an effective inhibitor for tyrosinase. Phenylthiourea can lead to graying of hair in black rats due to the interference with melanin formation[1][2].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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Phenylthiourea | 99.26% | Phenylthiourea (Phenylthiocarbamide) is an inhibitor for phenoloxidase. Phenylthiourea inhibits enzymatic oxidation of DOPA by phenoloxidase (Ki = 0.21 μM). Phenylthiourea is an effective inhibitor for tyrosinase. Phenylthiourea can lead to graying of hair in black rats due to the interference with melanin formation. | ||||||||||||||||||||
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Phenylbiguanide | 98.0% | Phenylbiguanide is a 5-HT3 receptor selective agonist with an EC50 of 3.0±0.1 μM. | ||||||||||||||||||||
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Phenylbiguanide hydrochloride | 99.96% | Phenylbiguanide hydrochloride is a 5-HT3 receptor selective agonist with an EC50 of 3.0±0.1 μM. | ||||||||||||||||||||
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Thioacetanilide | 98.35% | Thioacetanilide (N-Phenylthioacetamide) is a sulfur-containing thioamide derivative of acetanilide. Thioacetanilide displays a solvent‑dependent Z/E isomeric distribution, preferring the E conformation in polar hydrogen‑bonding solvents and the Z conformation in halogenated solvents. Thioacetanilide serves as a substrate for metabolic desulfurization and aromatic hydroxylation. Thioacetanilide is mainly metabolized via desulfurization and 4‑hydroxylation of the aromatic ring in Rattus norvegicus, and the released sulfur integrates into the total body sulfur pool. Thioacetanilide is well absorbed in rats, and more than 90% of the dose is excreted in urine as conjugated metabolites after oral administration. | ||||||||||||||||||||
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1-Phenylurea | 99.85% | 1-Phenylurea (Phenylurea) is a kind of biological materials or organic compounds that are widely used in life science research. | ||||||||||||||||||||
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Defenuron | Defenuron (IPO 4328) is a herbicide for controlling undesirable grasses and broad-leaved plants in a variety of crops. | |||||||||||||||||||||
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2-Iodo-N-phenylacetamide-13C6 | 98.98% | 2-Iodo-N-phenylacetamide-13C6 (N-phenyliodoacetamide-13C6) is the 13C labeled 2-Iodo-N-phenylacetamide. | ||||||||||||||||||||
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2,6-Dimethylphenylthiourea | 99.81% | 2,6-Dimethylphenylthiourea is a Xylazine metabolite. Xylazine is the first and most widely used α2-agonist. | ||||||||||||||||||||
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1-Phenylsemicarbazide | 97.0% | 1-Phenylsemicarbazide is an antifungal agent. 1-Phenylsemicarbazide has the potential for preventing mold growth on industrial products. | ||||||||||||||||||||
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References
- [1]. Ryazanova AD, et al. The phenylthiourea is a competitive inhibitor of the enzymatic oxidation of DOPA by phenoloxidase. J Enzyme Inhib Med Chem. 2012 Feb;27(1):78-83. [Content Brief]
- [2]. Frederick Bernheim & Mary L.C. Bernheim (1942) THE ACTION OF PHENYLTHIOCARBAMIDE ON TYROSINASE, Journal of Biological Chemistry, Volume 145, Issue 1, Pages 213-217, ISSN 0021-9258.
