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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
72 Results for "
coagulation protein
" in MedChemExpress (MCE) Product Catalog:
Products (72)
72 Results for "coagulation protein" in MCE Product Catalog:
9
Target:
Research Areas:
Thrombin (MW 37kDa) is a Na +-activated, allosteric serine protease that plays opposing functional roles in blood coagulation. Thrombin recognition sequence and can be used to digest GST-tagged proteins.
9
9 Cited Publications
Research Areas:
Rabbit Thrombin is a Na +-activated, allosteric serine protease that plays opposing functional roles in blood coagulation. Thrombin recognition sequence and can be used to digest GST-tagged proteins .
9
9 Cited Publications
Cat. No.: HY-114164D
CAS No.: 9002-04-4
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Research Areas:
Rat Thrombin is a Na +-activated, allosteric serine protease that plays opposing functional roles in blood coagulation. Thrombin recognition sequence and can be used to digest GST-tagged proteins .
9
9 Cited Publications
Cat. No.: HY-114164H
CAS No.: 9002-04-4
Synonyms: EC 3.4.21.5 (Lyophilized); Human Alpha Thrombin (Lyophilized)
Research Areas:
Human α-Thrombin (EC 3.4.21.5; Human Alpha Thrombin) (Lyophilized) is a terminal serine protease in the coagulation cascade, as well as a potent physiological platelet agonist and fibrin-generating enzyme in vivo. Human α-Thrombin catalyzes the conversion of fibrinogen to fibrin for blood clot formation, and activates platelet aggregation by cleaving the protease-activated receptors PAR1 (major) (Kd = 1 nM) and PAR4 (minor) on the platelet surface to expose tethered ligands. Human α-Thrombin also amplifies coagulation via positive feedback by activating coagulation factors V, VIII, XI (FV/FVIII/FXI), and switches to activate protein C to exert anticoagulant effects after binding to thrombomodulin .
This product is in a freeze-dried form.
This product is in a freeze-dried form.
2
2 Cited Publications
Cat. No.: HY-A0183
CAS No.: 1446756-47-3
Synonyms: Phospholipids, phosphatidylserines; Serine glycerophosphatides
Category:
Target:
2
2 Cited Publications
Cat. No.: HY-125864C
CAS No.: 9001-32-5
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Research Areas:
Porcine Fibrinogen is a coagulation protein, purified from porcine plasma with no plasminogen contained. Porcine Fibrinogen has excellent biocompatibility and does not induce aggregation of porcine platelets when in contact with porcine hepatocytes, aortic endothelial cells or hepatic sinusoidal endothelial cells. Porcine Fibrinogen is widely used in studies on the pathological mechanisms of cardiovascular diseases such as atherosclerosis and the development of related drugs .
1
1 Cited Publications
Cat. No.: HY-P701216
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: F2; coagulation Factor II (Thrombin); coagulation Factor II, Thrombin; Prothrombin B-Chain; Prothrombin; F2 protein; Prepro-coagulation Factor II; RPRGL2; coagulation Factor II; THPH1; Thrombin Factor II; PT
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P74238
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: F13B; Fibrin-Stabilizing Factor B Subunit; coagulation Factor XIII B Chain; Transglutaminase B Chain; FXIIIB; Alternative protein F13B; protein-Glutamine Gamma-Glutamyltransferase B Chain; TGase; coagulation Factor XIII, B Polypeptide
Species:
Human
Source:
HEK293
1
1
1 Cited Publications
Cat. No.: HY-P70231
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: F9; Autoprothrombin IIA; coagulation Factor IX; Coagulant Factor IX; FIX; Christmas Disease; Plasma Thromboplastic Component; Hemophilia B; Plasma Thromboplastin Component; Factor IX F9; Christmas Factor; Factor IX; PTC; Factor 9; Truncated coagulation Fa
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P77227
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TFPI; EPI; Prev. LACI; Tissue Factor Pathway Inhibitor (Lipoprotein-Associated coagulation Inhibitor); Extrinsic Pathway Inhibitor; Lipoprotein-Associated coagulation Inhibitor; TFPI1; Anti-Convertin; Tissue Factor Pathway Inhibitor; TFI
Species:
Human
Source:
HEK293
Cat. No.: HY-B2172
CAS No.: 12001-79-5
Category:
Cardiovascular Disease Natural Products other families Microorganisms Animals Plants Disease Research Fields
Target:
Target:
Cat. No.: HY-P2933
CAS No.: 42617-41-4
Research Areas:
Activated protein C is an anticoagulant targeting coagulation factors Va and VIIIa. Activated protein C demonstrates cytoprotective effects through binding to endothelial cell protein C receptor (EPCR) and protease-activated receptor-1 (PAR-1), regulating gene expression, anti-inflammation, anti-apoptosis, and stabilizing endothelial barriers. Activated protein C is promising for research of diseases such as severe sepsis and ischemic stroke .
Cat. No.: HY-P5372A
Research Areas:
Cat. No.: HY-D2460
Cat. No.: HY-P99769
CAS No.: 2249927-58-8
Synonyms: SCT-800
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Research Areas:
Cat. No.: HY-D2460A
Cat. No.: HY-D2460B
Cat. No.: HY-P5372
CAS No.: 211190-38-4
Research Areas:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
