1. Metabolic Enzyme/Protease
  2. Thrombin

Thrombin 

Cat. No.: HY-114164
Handling Instructions

Thrombin is a trypsin-like allosteric serine protease that has a fundamental role in the clotting cascade.

For research use only. We do not sell to patients.

Thrombin Chemical Structure

Thrombin Chemical Structure

CAS No. : 9002-04-4

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500 μg USD 60 In-stock
Estimated Time of Arrival: December 31

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Description

Thrombin is a trypsin-like allosteric serine protease that has a fundamental role in the clotting cascade.

In Vitro

Thrombin is a serine protease known to have a fundamental role in the clotting cascade. In addition, Thrombin also mediates several cellular processes through a unique family of protease-activated receptors (PARS), where PAR-1 is the prototype. Thrombin and PAR-1 are highly expressed in the brain and regulate synaptic transmission and plasticity[1]. Thrombin belongs to the chymotrypsin family and is generated by proteolytic cleavage of its inactive precursor prothrombin by the proThrombinase complex. Thrombin mediates the conversion of fibrinogen to fibrin, the main constituent of a blood clot. Furthermore, Thrombin activates the blood coagulation factors V, VIII, XI, XIII and the anticoagulant protein C[2].

References
CAS No.

9002-04-4

SMILES

[Thrombin]

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
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Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Thrombin
Cat. No.:
HY-114164
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Thrombin

Cat. No.: HY-114164