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coxsackievirus B3

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (1) DNA/RNA Synthesis (1) Drug Intermediate (1) Enterovirus (8) HCV (1) Influenza Virus (1) Monoamine Oxidase (3) NF-κB (1) Reference Standards (1) STAT (1)
By Research Areas:	Cancer (1) Cardiovascular Disease (1) Endocrinology (1) Infection (9) Inflammation/Immunology (1) Neurological Disease (2)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-100540

Golgicide A Maximum Cited Publications 11 Publications Verification GCA	Enterovirus	Infection Cancer
Golgicide A (GCA) is a potent, highly specific, and reversible inhibitor of the cis-Golgi ADP-ribosylation factor guanine nucleotide exchange factors (ArfGEF) GBF1 . Golgicide A drastically reduced replication of coxsackievirus B3 (CVB3) and other human enterovirus species .

HY-16561A

cis-Resveratrol 1 Publications Verification	Enterovirus NF-κB	Infection Inflammation/Immunology
cis-Resveratrol exhibits signifcant antiviral activity. cis-Resveratrol inhibits enteroviruses with IC₅₀s of 12.2 µM and 37.6 µM for coxsackievirus B3 (CVB3) and enterovirus 71 (EV71), respectively. cis-Resveratrol is the inhibitor for NF-κB signaling pathway .

HY-100679

Pirlindole	Monoamine Oxidase Enterovirus	Infection Neurological Disease
Pirlindole is a selective and reversible MAO-A inhibitor . Pirlindole is also an inhibitor of enterovirus-D68 and coxsackievirus B3 (CV-B3) .

HY-124806

TTP-8307 2 Publications Verification	Enterovirus DNA/RNA Synthesis HCV	Infection
TTP-8307 is a potent inhibitor of the replication of several rhino- and enteroviruses. TTP-8307 inhibits coxsackievirus B3 (CVB3; EC₅₀=1.2 μM) and poliovirus by interfering with the synthesis of viral RNA. TTP-8307 exerts antiviral activity through oxysterol-binding protein (OSBP) .

HY-100679A

Pirlindole mesylate	Monoamine Oxidase Enterovirus	Infection Endocrinology
Pirlindole mesylate is a selective and reversible MAO-A inhibitor. Pirlindole is also an inhibitor of enterovirus-D68 and coxsackievirus B3 (CV-B3) .

HY-33015A

4-Chlorocinnamaldehyde trans-p-Chlorocinnamaldehyde	Enterovirus	Infection
4-Chlorocinnamaldehyde (trans-p-Chlorocinnamaldehyde) is an antiviral agent. 4-Chlorocinnamaldehyde inhibits the replication of Coxsackievirus B3 in cardiomyocytes, but shows poor efficacy in animal experiments. 4-Chlorocinnamaldehyde can be used in studies related to viral myocarditis .

HY-W399940

Actiphenol	Antibiotic Influenza Virus Drug Intermediate	Infection
Actiphenol is an antibiotic against coxsackievirus B3 and influenza A virus (IC₅₀s = 14.37 and 34.4 µg/mL, respectively). Actiphenol is also an aromatic ketone that exhibits weak eukaryotic translation inhibiton activity, which is found in Streptomyces species. Actiphenol can be used as a key intermediate to synthesize Cycloheximide (HY-12320) .

HY-100679R

Pirlindole (Standard)	Reference Standards Monoamine Oxidase Enterovirus	Infection Neurological Disease
Pirlindole (Standard) is the analytical standard of Pirlindole. This product is intended for research and analytical applications. Pirlindole is a selective and reversible MAO-A inhibitor . Pirlindole is also an inhibitor of enterovirus-D68 and coxsackievirus B3 (CV-B3) .

HY-P11041

VS-IP1	STAT	Cardiovascular Disease
VS-IP1 is an interfering peptide that blocks viperin-mediated STAT1 degradation, thereby preventing coxsackievirus B3 (CVB3)-induced acute heart failure (AHF) .

HY-100540A

(Rac)-Golgicide A (Rac)-GCA	Enterovirus	Infection
(Rac)-Golgicide A ((Rac)-GCA) is a racemate of Golgicide A. Golgicide A (GCA) is a potent, highly specific, and reversible inhibitor of the cis-Golgi ADP-ribosylation factor guanine nucleotide exchange factors (ArfGEF) GBF1 .Golgicide A drastically reduced replication of coxsackievirus B3 (CVB3) and other human enterovirus species .

Cat. No.	Product Name	Target	Research Area

HY-P11041

VS-IP1	STAT	Cardiovascular Disease
VS-IP1 is an interfering peptide that blocks viperin-mediated STAT1 degradation, thereby preventing coxsackievirus B3 (CVB3)-induced acute heart failure (AHF) .

cis-Resveratrol 1 Publications Verification	Infection other families Classification of Application Fields Phenols Polyphenols Plants Disease Research Fields Source Classification	Enterovirus NF-κB
cis-Resveratrol exhibits signifcant antiviral activity. cis-Resveratrol inhibits enteroviruses with IC₅₀s of 12.2 µM and 37.6 µM for coxsackievirus B3 (CVB3) and enterovirus 71 (EV71), respectively. cis-Resveratrol is the inhibitor for NF-κB signaling pathway .

Actiphenol	Monophenols Microorganisms Phenols Source Classification	Antibiotic Influenza Virus Drug Intermediate
Actiphenol is an antibiotic against coxsackievirus B3 and influenza A virus (IC₅₀s = 14.37 and 34.4 µg/mL, respectively). Actiphenol is also an aromatic ketone that exhibits weak eukaryotic translation inhibiton activity, which is found in Streptomyces species. Actiphenol can be used as a key intermediate to synthesize Cycloheximide (HY-12320) .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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coxsackievirus B3

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