15 Results for "

coxsackievirus B3

" in MedChemExpress (MCE) Product Catalog:
Products (15)

15 Results for "coxsackievirus B3" in MCE Product Catalog:

11
11 Publications Verification
Cat. No.: HY-100540
CAS No.: 1139889-93-2
Purity:  99.94%
Synonyms: GCA
Target:  

Enterovirus

Research Areas:  

Infection Cancer

Golgicide A (GCA) is a potent, highly specific, and reversible inhibitor of the cis-Golgi ADP-ribosylation factor guanine nucleotide exchange factors (ArfGEF) GBF1 . Golgicide A drastically reduced replication of coxsackievirus B3 (CVB3) and other human enterovirus species .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-124806
CAS No.: 950225-08-8
Purity:  99.90%
Research Areas:  

Infection

TTP-8307 is a potent inhibitor of the replication of several rhino- and enteroviruses. TTP-8307 inhibits coxsackievirus B3 (CVB3; EC50=1.2 μM) and poliovirus by interfering with the synthesis of viral RNA. TTP-8307 exerts antiviral activity through oxysterol-binding protein (OSBP) .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-16561A
CAS No.: 61434-67-1
cis-Resveratrol exhibits signifcant antiviral activity. cis-Resveratrol inhibits enteroviruses with IC50s of 12.2 µM and 37.6 µM for coxsackievirus B3 (CVB3) and enterovirus 71 (EV71), respectively. cis-Resveratrol is the inhibitor for NF-κB signaling pathway .
loading...
    loading...
Cat. No.: HY-100679
CAS No.: 60762-57-4
Purity:  98.90%
Pirlindole is an orally active, selective and reversible MAO-A inhibitor with an IC50 value of 250 nM. Pirlindole inhibits genomic replication of Enterovirus species B and D, and exhibits moderate activity against enterovirus species A. Pirlindole inhibits MAO-A-mediated monoamine metabolism, promotes adult hippocampal neurogenesis, rescues stress-induced dendritic atrophy of hippocampal granule neurons, reverses behavioral effects associated with chronic mild stress, and also possesses anticonvulsant, analgesic, local anesthetic, hypotensive, antiplatelet aggregation and antispasmodic activities. Pirlindole shows no detectable mutagenic, clastogenic or carcinogenic properties. Pirlindole can be used in research related to depression and enterovirus infections .
loading...
    loading...
Cat. No.: HY-33015A
CAS No.: 49678-02-6
Synonyms: trans-p-Chlorocinnamaldehyde
Target:  

Enterovirus

Research Areas:  

Infection

4-Chlorocinnamaldehyde (trans-p-Chlorocinnamaldehyde) is an antiviral agent. 4-Chlorocinnamaldehyde inhibits the replication of Coxsackievirus B3 in cardiomyocytes, but shows poor efficacy in animal experiments. 4-Chlorocinnamaldehyde can be used in studies related to viral myocarditis .
loading...
    loading...
Cat. No.: HY-W399940
CAS No.: 526-02-3
Actiphenol is an antibiotic against coxsackievirus B3 and influenza A virus (IC50s = 14.37 and 34.4 µg/mL, respectively). Actiphenol is also an aromatic ketone that exhibits weak eukaryotic translation inhibiton activity, which is found in Streptomyces species. Actiphenol can be used as a key intermediate to synthesize Cycloheximide (HY-12320) .
loading...
    loading...
Cat. No.: HY-100679A
CAS No.: 207572-66-5
Pirlindole mesylate is an orally active, selective and reversible MAO-A inhibitor with an IC50 value of 250 nM. Pirlindole mesylate inhibits genomic replication of Enterovirus species B and D, and exhibits moderate activity against enterovirus species A. Pirlindole mesylate inhibits MAO-A-mediated monoamine metabolism, promotes adult hippocampal neurogenesis, rescues stress-induced dendritic atrophy of hippocampal granule neurons, reverses behavioral effects associated with chronic mild stress, and also possesses anticonvulsant, analgesic, local anesthetic, hypotensive, antiplatelet aggregation and antispasmodic activities. Pirlindole mesylate shows no detectable mutagenic, clastogenic or carcinogenic properties. Pirlindole mesylate can be used in research related to depression and enterovirus infections .
loading...
    loading...
Cat. No.: HY-P11041
Target:  

STAT

Research Areas:  

Cardiovascular Disease

VS-IP1 is an interfering peptide that blocks viperin-mediated STAT1 degradation, thereby preventing coxsackievirus B3 (CVB3)-induced acute heart failure (AHF) .
loading...
    loading...
Cat. No.: HY-100540A
CAS No.: 1005036-73-6
Synonyms: (Rac)-GCA
Target:  

Enterovirus

Research Areas:  

Infection

(Rac)-Golgicide A ((Rac)-GCA) is a racemate of Golgicide A. Golgicide A (GCA) is a potent, highly specific, and reversible inhibitor of the cis-Golgi ADP-ribosylation factor guanine nucleotide exchange factors (ArfGEF) GBF1 .Golgicide A drastically reduced replication of coxsackievirus B3 (CVB3) and other human enterovirus species .
loading...
    loading...
Cat. No.: HY-100679S
CAS No.: 1801646-26-3
Pirlindole-d4 is the d4-labeled Pirlindole (HY-100679). Pirlindole is an orally active, selective and reversible MAO-A inhibitor with an IC50 value of 250 nM. Pirlindole inhibits genomic replication of Enterovirus species B and D, and exhibits moderate activity against enterovirus species A. Pirlindole inhibits MAO-A-mediated monoamine metabolism, promotes adult hippocampal neurogenesis, rescues stress-induced dendritic atrophy of hippocampal granule neurons, reverses behavioral effects associated with chronic mild stress, and also possesses anticonvulsant, analgesic, local anesthetic, hypotensive, antiplatelet aggregation and antispasmodic activities. Pirlindole shows no detectable mutagenic, clastogenic or carcinogenic properties. Pirlindole can be used in research related to depression and enterovirus infections .
loading...
    loading...
Cat. No.: HY-100679R
CAS No.: 60762-57-4
Pirlindole (Standard) is the analytical standard of Pirlindole (HY-100679). This product is intended for research and analytical applications. Pirlindole is an orally active, selective and reversible MAO-A inhibitor with an IC50 value of 250 nM. Pirlindole inhibits genomic replication of Enterovirus species B and D, and exhibits moderate activity against enterovirus species A. Pirlindole inhibits MAO-A-mediated monoamine metabolism, promotes adult hippocampal neurogenesis, rescues stress-induced dendritic atrophy of hippocampal granule neurons, reverses behavioral effects associated with chronic mild stress, and also possesses anticonvulsant, analgesic, local anesthetic, hypotensive, antiplatelet aggregation and antispasmodic activities. Pirlindole shows no detectable mutagenic, clastogenic or carcinogenic properties. Pirlindole can be used in research related to depression and enterovirus infections .
loading...
    loading...
Cat. No.: HY-P76280
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: coxsackievirus A16 (Cox A16) (strain G-10) VP4 Protein; VP1 Protein; CV3B; 3D; VP1 (1D); VP2 (1B); VP3 (1C); VP4 (1A); protease 2A; protease 3C; protein 2C; protein 3A; protien 2B
Species:  
Virus
Source:  
Sf9 insect cells
loading...
    loading...
Cat. No.: HY-P76281
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: coxsackievirus A16 (Cox A16) (strain G-10) VP4 Protein; VP1 Protein; CV3B; 3D; VP1 (1D); VP2 (1B); VP3 (1C); VP4 (1A); protease 2A; protease 3C; protein 2C; protein 3A; protien 2B
Species:  
Virus
Source:  
Sf9 insect cells
loading...
    loading...
Cat. No.: HY-W279140
CAS No.: 16154-78-2
Synonyms: Pyrazidole hydrochloride; Pirazidole hydrochloride
Pirlindole hydrochloride is an orally active, selective and reversible MAO-A inhibitor with an IC50 value of 250 nM. Pirlindole hydrochloride inhibits genomic replication of Enterovirus species B and D, and exhibits moderate activity against enterovirus species A. Pirlindole hydrochloride inhibits MAO-A-mediated monoamine metabolism, promotes adult hippocampal neurogenesis, rescues stress-induced dendritic atrophy of hippocampal granule neurons, reverses behavioral effects associated with chronic mild stress, and also possesses anticonvulsant, analgesic, local anesthetic, hypotensive, antiplatelet aggregation and antispasmodic activities. Pirlindole hydrochloride shows no detectable mutagenic, clastogenic or carcinogenic properties. Pirlindole hydrochloride can be used in research related to depression and enterovirus infections .
loading...
    loading...
Cat. No.: HY-167152
CAS No.: 292039-20-4
Pirlindole lactate is an orally active, selective and reversible MAO-A inhibitor with an IC50 value of 250 nM. Pirlindole lactate inhibits genomic replication of Enterovirus species B and D, and exhibits moderate activity against enterovirus species A. Pirlindole lactate inhibits MAO-A-mediated monoamine metabolism, promotes adult hippocampal neurogenesis, rescues stress-induced dendritic atrophy of hippocampal granule neurons, reverses behavioral effects associated with chronic mild stress, and also possesses anticonvulsant, analgesic, local anesthetic, hypotensive, antiplatelet aggregation and antispasmodic activities. Pirlindole lactate shows no detectable mutagenic, clastogenic or carcinogenic properties. Pirlindole lactate can be used in research related to depression and enterovirus infections .
loading...
    loading...
  • 1