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dauer formation

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By Targets:	Drug Derivative (1) Endogenous Metabolite (2) Reference Standards (3)
By Research Areas:	Endocrinology (2) Infection (2)

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Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N6974

Ascr#2 Ascaroside C6	Endogenous Metabolite	Endocrinology
Ascr#2 (Ascaroside C6) is an ascaroside isolated from Caenorhabditis elegans, potently promotes dauer formation, and also acts as a potent male attractant combined with Ascr#3 (HY-N6977) at low concentration .

HY-N9441

Ascr#7	Others	Others
Ascr#7, an ascaroside, is a hormone of nematodes. Ascr#7 is expressed during nematode development. Ascarosides can induce formation of long-lived and highly stress resistant dauer larvae .

HY-N6977

Ascr#3	Others	Infection
Ascr#3 is a type of pheromone found in the beautiful nematode, and when mixed with ascr#2, it can act as a male attractant and also induce the formation of dauer (the dormant larval stage). Ascr#3 can counteract the effects caused by male-enriched Ascr#10 .

HY-N9441R

Ascr#7 (Standard)	Others Reference Standards	Others
Ascr#7 (Standard) is the analytical standard of Ascr#7 (HY-N9441). This product is intended for research and analytical applications. Ascr#7, an ascaroside, is a hormone of nematodes. Ascr#7 is expressed during nematode development. Ascarosides can induce formation of long-lived and highly stress resistant dauer larvae .

HY-171721

Ascr#14 Asc-C8	Drug Derivative	Others
Ascr#14 (Asc-C8) is an ascaroside derivative that exhibits low activity in inducing the dauer (dormant larval) stage .

HY-N6974R

Ascr#2 (Standard) Ascaroside C6 (Standard)	Endogenous Metabolite Reference Standards	Endocrinology
Ascr#2 (Standard) (Ascaroside C6 (Standard)) is the analytical standard of Ascr#2 (HY-N6974). This product is intended for research and analytical applications. Ascr#2 (Ascaroside C6) is an ascaroside isolated from Caenorhabditis elegans, potently promotes dauer formation, and also acts as a potent male attractant combined with Ascr#3 (HY-N6977) at low concentration .

HY-N6977R

Ascr#3 (Standard)	Others Reference Standards	Infection
Ascr#3 (Standard) is the analytical standard of Ascr#3 (HY-N6977). This product is intended for research and analytical applications. Ascr#3 is a type of pheromone found in the beautiful nematode, and when mixed with ascr#2, it can act as a male attractant and also induce the formation of dauer (the dormant larval stage). Ascr#3 can counteract the effects caused by male-enriched Ascr#10 .

Ascr#2 Ascaroside C6	Infection Natural Products Animals Classification of Application Fields Disease Research Fields Source Classification	Endogenous Metabolite
Ascr#2 (Ascaroside C6) is an ascaroside isolated from Caenorhabditis elegans, potently promotes dauer formation, and also acts as a potent male attractant combined with Ascr#3 (HY-N6977) at low concentration .

Ascr#7	Animals Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Disease Research Fields Source Classification	Others
Ascr#7, an ascaroside, is a hormone of nematodes. Ascr#7 is expressed during nematode development. Ascarosides can induce formation of long-lived and highly stress resistant dauer larvae .

Ascr#3	Infection Natural Products Animals Classification of Application Fields Disease Research Fields Source Classification	Others
Ascr#3 is a type of pheromone found in the beautiful nematode, and when mixed with ascr#2, it can act as a male attractant and also induce the formation of dauer (the dormant larval stage). Ascr#3 can counteract the effects caused by male-enriched Ascr#10 .

Ascr#7 (Standard)	Structural Classification Animals Ketones, Aldehydes, Acids Source Classification	Others Reference Standards
Ascr#7 (Standard) is the analytical standard of Ascr#7 (HY-N9441). This product is intended for research and analytical applications. Ascr#7, an ascaroside, is a hormone of nematodes. Ascr#7 is expressed during nematode development. Ascarosides can induce formation of long-lived and highly stress resistant dauer larvae .

Ascr#2 (Standard) Ascaroside C6 (Standard)	Structural Classification Natural Products Animals Source Classification	Endogenous Metabolite Reference Standards
Ascr#2 (Standard) (Ascaroside C6 (Standard)) is the analytical standard of Ascr#2 (HY-N6974). This product is intended for research and analytical applications. Ascr#2 (Ascaroside C6) is an ascaroside isolated from Caenorhabditis elegans, potently promotes dauer formation, and also acts as a potent male attractant combined with Ascr#3 (HY-N6977) at low concentration .

Ascr#3 (Standard)	Structural Classification Natural Products Animals Source Classification	Others Reference Standards
Ascr#3 (Standard) is the analytical standard of Ascr#3 (HY-N6977). This product is intended for research and analytical applications. Ascr#3 is a type of pheromone found in the beautiful nematode, and when mixed with ascr#2, it can act as a male attractant and also induce the formation of dauer (the dormant larval stage). Ascr#3 can counteract the effects caused by male-enriched Ascr#10 .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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dauer formation

Inhibitors & Agonists

NaturalProducts

Natural
Products