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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
308 Results for "
drosophila
" in MedChemExpress (MCE) Product Catalog:
Products (308)
308 Results for "drosophila" in MCE Product Catalog:
313
313 Publications Verification
Synonyms: EX-527
Target:
Research Areas:
Selisistat (EX-527) is a potent and selective SirT1 (Sir2 in Drosophila melanogaster) inhibitor with an IC50 of 123 nM for SirT1. Selisistat alleviates pathology in multiple animal and cell models of Huntington's disease .
37
37 Cited Publications
37
37 Cited Publications
Target:
Research Areas:
BAPTA tetrasodium is a selective and cell-impermeant chelator for calcium. BAPTA tetrasodium has high selectivity against magnesium and calcium. BAPTA can also inhibit phospholipase C activity independently of their role as Ca 2+ chelators .
37
37 Cited Publications
3
3 Cited Publications
Cat. No.: HY-P7409
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SHH; Shh Unprocessed N-Terminal Signaling And C-Terminal Autoprocessing Domains; Prev. HLP3; Sonic Hedgehog Protein; Prev. HPE3; ShhNC; MCOPCB5; Sonic Hedgehog (drosophila) Homolog; SMMCI; Sonic Hedgehog Homolog; TPTPS; Hedgehog Protein; HHG1; HHG-1; TPT
Species:
Mouse
Source:
E. coli
3
3 Cited Publications
Cat. No.: HY-P80324
Synonyms: drosophila, homolog of, MADR2 antibody;
hMAD-2 antibody;
JV181 antibody;
MAD antibody;
MAD homolog 2 antibody;
MADH2 antibody;
MADR2 antibody;
MGC22139 antibody;
SMAD 2 antibody;
SMAD family member 2 antibody;
SMAD2 antibody
3
3 Cited Publications
Cat. No.: HY-P76550
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PLK1; STPK13; Prev. PLK; Cell Cycle Regulated Protein Kinase; Serine/Threonine-Protein Kinase PLK1; Polo-Like Kinase (drosophila); Polo-Like Kinase 1; Polo (Drosophia)-Like Kinase; Serine/Threonine-Protein Kinase 13; Polo Like Kinase 1; PLK-1
Species:
Human
Source:
Sf9 insect cells
2
2 Cited Publications
Target:
Research Areas:
Chlorantraniliprole is an insecticide that potently and selectively activates insect ryanodine receptor, with EC50s of 40 nM and 50 nM for Drosophila melanogaster and H. virescens ryanodine receptor, and ～300-fold more potent than that in the mouse myoblast cell line, C2C12 (EC50, 14 μM).
2
2 Cited Publications
Cat. No.: HY-P70467
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SHH; Shh Unprocessed N-Terminal Signaling And C-Terminal Autoprocessing Domains; Prev. HLP3; Sonic Hedgehog Protein; Prev. HPE3; ShhNC; MCOPCB5; Sonic Hedgehog (drosophila) Homolog; SMMCI; Sonic Hedgehog Homolog; TPTPS; Hedgehog Protein; HHG1; HHG-1; TPT
Species:
Human
Source:
E. coli
2
2 Cited Publications
Cat. No.: HY-P81210
Synonyms: LATS1 +LATS2 (phospho T1079 + T1041); Serine/threonine protein kinase LATS2; KPM; Large tumor supressor, homolog 1; LATS, large tumor suppressor, homolog 1 (drosophila); LATS, large tumor suppressor, homolog 2 (drosophila); LATS1 +LATS2 (phospho T1079 + T1041); p-LATS1 +LATS2(Thr1079 +Thr1041); RGD1564085; Serine/threonine protein kinase LATS1; WARTS; WARTS protein kinase; wts; 4932411G09Rik; AV277261; AW208599; AW228608; FLJ13161; LATS1_HUMAN.
2
2 Cited Publications
Cat. No.: HY-P701625
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: KAT8; Protein Acetyltransferase KAT8; Prev. MYST1; FLJ14040; HMOF; ZC2HC8; MOF; MYST-1; Males-Absent On The First Protein Homolog; Ortholog Of drosophila Males Absent On The First (MOF); MOZ, YBF2/SAS3, SAS2 And TIP60 Protein 1; Probable Histone Acetyltra
Species:
Human
Source:
E. coli
2
2 Cited Publications
Cat. No.: HY-P74742
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: STK4; Kinase Responsive To Stress 2; Serine/Threonine Kinase 4; Mammalian Sterile 20-Like 1; MST1; STE20-Like Kinase MST1; KRS2; Non-Specific Serine/Threonine Protein Kinase; YSK3; Hippo (drosophila) Homolog; Mammalian STE20-Like Protein Kinase 1; Yeast S
Species:
Human
Source:
Sf9 insect cells
1
1 Cited Publications
Target:
Research Areas:
Lotilaner is a parasiticide, acts as a potent non-competitive antagonist of insects GABACl receptors, with an IC50 of 23.84 nM for Drosophila melanogaster GABA receptor. No effect on a dog GABAA receptor .
1
1 Cited Publications
Target:
Research Areas:
SecinH3 is an antagonist of cytohesins with IC50s of 5.4 μM, 2.4 μM, 5.4 μM, 5.6 μM, 5.6 μM and 65 μM for hCyh1, hCyh2, mCyh3, hCyh3, drosophila steppke and yGea2-S7, respectively.
1
1 Cited Publications
Cat. No.: HY-18399
CAS No.: 409086-68-6
Target:
Research Areas:
YM-1 is a stable MKT-077 (HY-15096) analog and an orally active Hsp70 inhibitor. YM-1 induces cell death of HeLa cells and up-regulates the level of p53 and p21 proteins .
1
Category:
Infection Microorganisms Cyclopeptides Disease Research Fields Biological Pesticide Research Agricultural Research
Target:
1
1 Cited Publications
Cat. No.: HY-P78009
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: NOTCH3; Notch 3-Like Protein; Prev. CADASIL; CADASIL1; Notch 3; CARASIL1; CASIL; FPLD1; Neurogenic Locus Notch Homolog Protein 3; IMF2; Notch (drosophila) Homolog 3; LMNS; Notch Homolog 3 (drosophila); Notch Receptor 3; Notch Homolog 3
Species:
Human
Source:
HEK293
1
1 Cited Publications
dTAG-47 is a heterobifunctional PROTAC degrader that specifically binds to the FKBP12 F36V domain and Cereblon (CRBN). By recruiting the CRBN E3 ubiquitin ligase, dTAG-47 induces ubiquitination and proteasomal degradation of FKBP12 F36V-fused Cas9 and tagged KDM5A. dTAG-47 can induce upregulated expression of some endogenous retrovirus (ERV) genes and is suitable for cancer research .
1
1 Cited Publications
Cat. No.: HY-P79357
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NOTUM; HNOTUM; Notum, Palmitoleoyl-Protein Carboxylesterase; Notum Pectinacetylesterase Homolog (drosophila); [Wnt Protein] O-Palmitoleoyl-L-Serine Hydrolase; Notum Pectinacetylesterase Homolog; Palmitoleoyl-Protein Carboxylesterase NOTUM; Protein Notum H
Species:
Human
Source:
CHO
1
1 Cited Publications
Cat. No.: HY-P80155
Synonyms: bHLHb39 antibody;
C-HAIRY1 antibody;
Class B basic helix-loop-helix protein 39 antibody;
FLJ20408 antibody;
Hairy and enhancer of split 1 antibody;
Hairy homolog (drosophila) antibody;
Hairy homolog antibody;
Hairy like antibody;
Hairy, drosophila, homolog of antibody;
Hairy-like protein antibody;
HAIRY1 antibody;
HES-1 antibody;
HES1_HUMAN antibody;
HHL antibody;
HL antibody;
HRY antibody;
MGC129109 antibody;
OTTHUMP00000209031 antibody;
RHL antibody;
Transcription factor HES-1 antibody
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
