12 Results for "

fumarate

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "fumarate" in MCE Product Catalog:

7
7 Publications Verification
Cat. No.: HY-103252
CAS No.: 2756-87-8
Purity:  99.95%
Monomethyl fumarate, an active metabolite of Dimethyl fumarate (DMF), is a potent GPR109A agonist. Monomethyl fumarate has the potential for multiple neuroprotective pathways and other models of retinal disease .
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1 Cited Publications
Cat. No.: HY-103252S
CAS No.: 1616345-41-5
Purity:  98.24%
Monomethyl fumarate-d3 is a deuterium labeled Monomethyl fumarate (HY-103252). Monomethyl fumarate, an active metabolite of Dimethyl fumarate (DMF) (HY-17363), is a potent GPR109A agonist. Monomethyl fumarate has the potential for multiple neuroprotective pathways and other models of retinal disease .
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1 Cited Publications
Cat. No.: HY-19946
CAS No.: 179756-58-2
Synonyms: F 11440
Target:  

5-HT Receptor

Research Areas:  

Neurological Disease

Eptapirone (F11440) is a potent, selective and orally active 5-HT1A receptor agonist (pKi = 8.33). Eptapirone can inhibit cAMP production. Eptapirone can reduce 5-HT levels and increase corticosterone levels. Eptapirone shows potent anxiolytic and antidepressant potential. Eptapirone can be used for the research of neurological disease, such as anxiety and depression .
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Cat. No.: HY-W040996R
CAS No.: 5333-42-6
Research Areas:  

Others

2-Octyldodecanol (Standard) is the analytical standard of 2-Octyldodecanol. This product is intended for research and analytical applications. 2-Octyldodecanol can enhance the skin permeation of formoterol fumarate (HY-B0010) .
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Cat. No.: HY-W040996
CAS No.: 5333-42-6
Research Areas:  

Others

2-Octyldodecanol can enhance the skin permeation of formoterol fumarate (HY-B0010) .
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Cat. No.: HY-176568
LCL768 is a ceramide analog. LCL768 attenuates PARKIN succination to promote PARKIN activation and mitophagy. LCL768 induces CerS1-mediated endogenous C18-ceramide accumulation in mitochondria to mediate mitophagy, which is dependent on DRP1 activation via nitrosylation at C644. LCL768 alters mitochondrial metabolism, resulting in fumarate depletion and leading to tumor suppression. LCL768 improves sensorimotor defects in neurodegenerative diseases like ALS .
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Cat. No.: HY-78036R
CAS No.: 498-24-8
Synonyms: Citronic acid (Standard); Methylfumaric acid (Standard)
Mesaconic acid (Standard) is the analytical standard of Mesaconic acid. This product is intended for research and analytical applications. Mesaconic acid (Citronic acid; Methylfumaric acid) is an orally active anti-inflammatory and antioxidant agent. Mesaconic acid reduces the level of NF-κB in colon tissues, downregulates the expression of Keap1 and Bax, upregulates the expression of Nrf2 and Bcl2, and decreases the expression of Caspase-1. Mesaconic acid reduces the levels of NLRP3, ASC and Casp-1 in colon, liver and kidney tissues. Mesaconic acid reduces pro-inflammatory cytokine levels, increases the level of the anti-inflammatory cytokine IL-10, elevates NAD + levels, regulates oxidative stress markers and antioxidant enzyme levels, and upregulates intestinal barrier proteins in colon, liver and kidney tissues. Mesaconic acid increases the abundance of beneficial gut bacteria and reduces the abundance of harmful gut bacteria in rapidly aging mice, and exhibits anti-aging properties. Mesaconic acid acts as a flame retardant and serves as a competitive inhibitor of fumarate reduction. Mesaconic acid can be used in the research of aging-related inflammation .
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Cat. No.: HY-103252R
CAS No.: 2756-87-8
Monomethyl fumarate (Standard) is the analytical standard of Monomethyl fumarate. This product is intended for research and analytical applications. Monomethyl fumarate, an active metabolite of Dimethyl fumarate (DMF), is a potent GPR109A agonist. Monomethyl fumarate has the potential for multiple neuroprotective pathways and other models of retinal disease[1][2][3].
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Cat. No.: HY-19946A
CAS No.: 179756-85-5
Synonyms: F 11440 fumarate
Target:  

5-HT Receptor

Research Areas:  

Neurological Disease

Eptapirone fumarate (F11440 fumarate) is a potent, selective and orally active 5-HT1A receptor agonist (pKi = 8.33). Eptapirone fumarate can inhibit cAMP production. Eptapirone fumarate can reduce 5-HT levels and increase corticosterone levels. Eptapirone fumarate shows potent anxiolytic and antidepressant potential. Eptapirone fumarate can be used for the research of neurological disease, such as anxiety and depression .
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Cat. No.: HY-K0321

MCE Fumarase Activity Assay Kit (WST-8) can be used to measure the amount of fumarase present in biological samples.

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Cat. No.: HY-W032878
CAS No.: 2372-82-9
Target:  

Fungal SOD

Research Areas:  

Infection

N,N-Bis(3-aminopropyl)dodecylamine is a potent fungicidal agent with remarkable activity against Aspergillus niger. N,N-Bis(3-aminopropyl)dodecylamine induces oxidative stress and regulates the activities of multiple antioxidant and mitochondrial enzymes in a concentration‑ and duration‑dependent manner. N,N-Bis(3-aminopropyl)dodecylamine disrupts fungal organelles, remodels mitochondrial morphology and impairs mitochondria‑related cellular functions. N,N-Bis(3-aminopropyl)dodecylamine can be used for the research of fungicidal mechanisms and oxidative stress in Aspergillus niger .
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Cat. No.: HY-N19720
CAS No.: 22684-08-8
Bractein is a natural aurone flavonoid with potential antioxidant activity. Bractein shows in vitro antileishmanial activity and inhibits promastigotes and intracellular amastigotes of Leishmania donovani. Bractein exhibits no obvious cytotoxicity against mammalian macrophages with an EC50 value > 25.0 μg/mL. Bractein can be used for the research of Leishmania .
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