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fumarate

" in MedChemExpress (MCE) Product Catalog:

12

Inhibitors & Agonists

1

MCE Kits

3

Natural
Products

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-103252
    Monomethyl fumarate
    5+ Cited Publications

    		 GPR109A Drug Metabolite Neurological Disease Inflammation/Immunology
    Monomethyl fumarate, an active metabolite of Dimethyl fumarate (DMF), is a potent GPR109A agonist. Monomethyl fumarate has the potential for multiple neuroprotective pathways and other models of retinal disease .
    Monomethyl fumarate
  • HY-78036
    Mesaconic acid

    Citronic acid; Methylfumaric acid

    		 Endogenous Metabolite Others
    Mesaconic acid is an active product that can be extracted from Saxifraga stolonifera. Mesaconic acid is used as a fire retardant and is a competitive inhibitor of fumarate reduction .
    Mesaconic acid
  • HY-W040996R
    2-Octyldodecanol (Standard)

    		Biochemical Assay Reagents Reference Standards Others
    2-Octyldodecanol (Standard) is the analytical standard of 2-Octyldodecanol. This product is intended for research and analytical applications. 2-Octyldodecanol can enhance the skin permeation of formoterol fumarate (HY-B0010) .
    2-Octyldodecanol (Standard)
  • HY-W040996
    2-Octyldodecanol

    		Environmental Pollutants Others
    2-Octyldodecanol can enhance the skin permeation of formoterol fumarate (HY-B0010) .
    2-Octyldodecanol
  • HY-103252S
    Monomethyl fumarate-d3
    1 Publications Verification

    		 GPR109A Isotope-Labeled Compounds Drug Metabolite Neurological Disease Inflammation/Immunology
    Monomethyl fumarate-d3 is a deuterium labeled Monomethyl fumarate (HY-103252). Monomethyl fumarate, an active metabolite of Dimethyl fumarate (DMF) (HY-17363), is a potent GPR109A agonist. Monomethyl fumarate has the potential for multiple neuroprotective pathways and other models of retinal disease .
    Monomethyl fumarate-d3
  • HY-19946
    Eptapirone

    F 11440

    		 5-HT Receptor Neurological Disease
    Eptapirone (F11440) is a potent, selective and orally active 5-HT1A receptor agonist (pKi = 8.33). Eptapirone can inhibit cAMP production. Eptapirone can reduce 5-HT levels and increase corticosterone levels. Eptapirone shows potent anxiolytic and antidepressant potential. Eptapirone can be used for the research of neurological disease, such as anxiety and depression .
    Eptapirone
  • HY-176568
    LCL768

    		Mitophagy PINK1/Parkin Mitochondrial Metabolism Neurological Disease Cancer
    LCL768 is a ceramide analog. LCL768 attenuates PARKIN succination to promote PARKIN activation and mitophagy. LCL768 induces CerS1-mediated endogenous C18-ceramide accumulation in mitochondria to mediate mitophagy, which is dependent on DRP1 activation via nitrosylation at C644. LCL768 alters mitochondrial metabolism, resulting in fumarate depletion and leading to tumor suppression. LCL768 improves sensorimotor defects in neurodegenerative diseases like ALS .
    LCL768
  • HY-78036R
    Mesaconic acid (Standard)

    Citronic acid (Standard); Methylfumaric acid (Standard)

    		 Endogenous Metabolite Reference Standards Others
    Mesaconic acid (Standard) is the analytical standard of Mesaconic acid. This product is intended for research and analytical applications. Mesaconic acid is an active product that can be extracted from Saxifraga stolonifera. Mesaconic acid is used as a fire retardant and is a competitive inhibitor of fumarate reduction[1].
    Mesaconic acid (Standard)
  • HY-103252R
    Monomethyl fumarate (Standard)

    		Reference Standards GPR109A Drug Metabolite Neurological Disease Inflammation/Immunology
    Monomethyl fumarate (Standard) is the analytical standard of Monomethyl fumarate. This product is intended for research and analytical applications. Monomethyl fumarate, an active metabolite of Dimethyl fumarate (DMF), is a potent GPR109A agonist. Monomethyl fumarate has the potential for multiple neuroprotective pathways and other models of retinal disease[1][2][3].
    Monomethyl fumarate (Standard)
  • HY-19946A
    Eptapirone fumarate

    F 11440 fumarate

    		 5-HT Receptor Neurological Disease
    Eptapirone fumarate (F11440 fumarate) is a potent, selective and orally active 5-HT1A receptor agonist (pKi = 8.33). Eptapirone fumarate can inhibit cAMP production. Eptapirone fumarate can reduce 5-HT levels and increase corticosterone levels. Eptapirone fumarate shows potent anxiolytic and antidepressant potential. Eptapirone fumarate can be used for the research of neurological disease, such as anxiety and depression .
    Eptapirone fumarate
  • HY-W032878
    N,N-Bis(3-aminopropyl)dodecylamine

    		Fungal SOD Infection
    N,N-Bis(3-aminopropyl)dodecylamine is a potent fungicidal agent with remarkable activity against Aspergillus niger. N,N-Bis(3-aminopropyl)dodecylamine induces oxidative stress and regulates the activities of multiple antioxidant and mitochondrial enzymes in a concentration‑ and duration‑dependent manner. N,N-Bis(3-aminopropyl)dodecylamine disrupts fungal organelles, remodels mitochondrial morphology and impairs mitochondria‑related cellular functions. N,N-Bis(3-aminopropyl)dodecylamine can be used for the research of fungicidal mechanisms and oxidative stress in Aspergillus niger .
    N,N-Bis(3-aminopropyl)dodecylamine
  • HY-N19720
    Bractein

    		Drug Derivative Parasite Infection
    Bractein is a natural aurone flavonoid with potential antioxidant activity. Bractein shows in vitro antileishmanial activity and inhibits promastigotes and intracellular amastigotes of Leishmania donovani. Bractein exhibits no obvious cytotoxicity against mammalian macrophages with an EC50 value > 25.0 μg/mL. Bractein can be used for the research of Leishmania .
    Bractein

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