53 Results for "

glycerophospholipids

" in MedChemExpress (MCE) Product Catalog:
Products (53)

53 Results for "glycerophospholipids" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-W013707
CAS No.: 81012-87-5
Synonyms: Cytidine triphosphate disodium dihydrate; 5'-CTP disodium dihydrate
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Cytidine-5'-triphosphate disodium dihydrate (5'-CTP disodium dihydrate) is a molecule of high energy, and acts as a coenzyme in glycerophospholipid biosynthesis and protein glycosylation .
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2
2 Cited Publications
Cat. No.: HY-122949
CAS No.: 91590-76-0
Purity:  ≥97.0%
Momordicine I is a cucurbitane-type triterpenoids. Momordicine I suppresses glioma growth by promoting apoptosis and impairing mitochondrial oxidative phosphorylation. Momordicine I inhibits glycolysis, lipid metabolism, induces autophagy in HNC cells to suppress head and neck cancer growth. Momordicine I alleviates isoproterenol-induced cardiomyocyte hypertrophy through suppression of PLA2G6 and DGK-ζ. Momordicine I exerts its cardiovascular benefits by upregulating nitric oxide, inhibiting the activity of angiotensin-converting enzyme (ACE), activating the PI3K/Akt pathway, reducing oxidative stress and inflammation. Momordicine I inhibits AKT1, IL-6, and SRC, suggesting its potential application in type 2 diabetes .
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2
2 Cited Publications
Cat. No.: HY-P2733D
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Glycerol 3-phosphate Oxidase, Streptococcus thermophilus (EC 1.1.3.21), is an oxidoreductase that acts on the CH-OH group in donor molecules and uses oxygen as an acceptor. Glycerol 3-phosphate Oxidase participates in glycerophospholipid metabolism and utilizes a cofactor, FAD. The two substrates of Glycerol 3-phosphate Oxidase are sn-glycerol-3-phosphate and O2, while its two products are glycerophosphate and H2O2.
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1
1 Cited Publications
Cat. No.: HY-P3029
CAS No.: 9001-84-7
Synonyms: PLA2
Phospholipase A2 (PLA2) is a calcium-dependent, heat-stable enzyme that catalyzes the hydrolysis of glycerophospholipids at the sn-2 position of cellular membranes, thereby releasing Arachidonic Acid (AA) (HY-109590). Phospholipase A2 is a key mediator in the biosynthesis of pro-inflammatory lipid mediators, critically involved in inflammatory processes. Phospholipase A2 can be used for cardiovascular and inflammatory diseases research .
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1
1 Cited Publications
Cat. No.: HY-N7814
CAS No.: 764-67-0
2-Hydroxypalmitic acid is an intermediate in the phytosphingosine metabolic pathway. 2-Hydroxypalmitic acid is exclusively incorporated into sphingolipids and not used for other lipids. 2-Hydroxypalmitic acid promotes the production of odd-carbon phosphatidylcholine species. 2-Hydroxypalmitic acid is applicable to studies of Saccharomyces cerevisiae infection .
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Cat. No.: HY-P2812
CAS No.: 9001-87-0
Synonyms: PLD
Phospholipase D, Streptomyces chromofuscus (PLD) is an enzyme of the phospholipase superfamily, which widely exists in bacteria, yeast, plants, animals and viruses, and is often used in biochemical research. Phospholipase D can catalyze the hydrolysis of phosphodiester bonds in glycerophospholipids to produce phosphatidic acid and soluble choline. Phospholipase D is involved in a variety of disease-related processes, including diabetes, atherogenesis, obesity, tumorigenesis, immune response, and neuroendocrine function .
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Cat. No.: HY-148123
CAS No.: 39382-08-6
Purity:  88.59%
Glycerophospholipids and cephalins are a class of phospholipid compounds and important components of neural membranes. Glycerophospholipids and cephalins are hydrolysis substrates of phospholipase (such as PLA2, PLC, and PLD). After complete hydrolysis, they produce 1 mol of glycerol, phosphate, ethanolamine, and 2 mol of fatty acids, respectively. Glycerophospholipids and cephalins can maintain membrane structure, fluidity, and ion permeability, and serve as precursors of second messengers such as arachidonic acid and diacylglycerol. Glycerophospholipids and cephalins can regulate signal transduction, cell apoptosis, and membrane transport, and are used in the study of neurodegenerative diseases (such as Alzheimer's disease) .
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Cat. No.: HY-145469
CAS No.: 1219038-31-9
Purity:  95.20%
Synonyms: ω-Alkynyl linoleic acid
Linoleic acid alkyne is an ω-alkyne derivative of Linoleic acid (HY-N0729). Linoleic acid alkyne can be used to synthesize other alkyne-containing products,such as glycerophospholipids, for click chemistry .
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Cat. No.: HY-124370
CAS No.: 13058-52-1
Purity:  99.2%
Synonyms: 9Z,11E-CLA; Methyl 9(Z),11(E)-octadecadienoate; (9Z,11E)-SFE 19:2
Target:  

Endogenous Metabolite

Research Areas:  

Cardiovascular Disease Cancer

9 (Z),11 (E)-Conjugated linoleic acid methyl ester (9Z,11E-CLA; Methyl 9 (Z),11 (E)-octadecadienoate; (9Z,11E)-SFE 19:2) is an isomer of Linoleic acid (HY-N0729), and is a conjugated linoleic acid mainly found in meat and dairy products. Conjugated linoleic acid is a bioactive fatty acid that improves body composition, enhances immune system function, and exhibits anti-cancer and anti-atherosclerotic effects .
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Cat. No.: HY-126359
CAS No.: 27098-24-4
Purity:  ≥98.0%
Synonyms: SLPC; 18:0-18:2 PC
1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine (SLPC; 18:0-18:2 PC) is an endogenous phospholipid marker molecule in the glycerophospholipid metabolic pathway. 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine is a core component of the phospholipid bilayer of biological membranes and a key responsive lipid for radiation injury and cardiometabolic diseases. 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine constitutes the phospholipid bilayers of cell membranes and high-density lipoprotein (HDL), and regulates the core activity of lipoprotein functional homeostasis. The content of 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine in mouse serum shows a significant dose-dependent decrease with increasing ionizing radiation dose, and its level in human HDL also decreases significantly in metabolic syndrome. 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine can serve as a biological dosimeter marker for ionizing radiation injury, and is used for rapid and accurate assessment of radiation absorbed dose in exposed individuals. 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine can also act as a lipidomics research target for cardiometabolic diseases such as lipid metabolic syndrome and early-onset coronary heart disease .
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Cat. No.: HY-147072
CAS No.: 322647-11-0
Synonyms: 18:0 -18:2 PS
Target:  

Liposome

Research Areas:  

Others

1-Stearoyl-2-linoleoyl-sn-glycero-3-phospho-L-serine sodium is a glycerophospholipid .
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Cat. No.: HY-143203
CAS No.: 7266-53-7
Purity:  ≥98.0%
Synonyms: 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine
Target:  

Liposome

Research Areas:  

Cardiovascular Disease Cancer

18:0-18:2 PE (1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine) is a glycerophospholipid compound and an essential component of biological cell membranes. 18:0-18:2 PE possesses biological activities including regulation of phospholipid metabolism, antioxidant activity, maintenance of cell membrane fluidity, immune protection, and regulation of signaling pathways. 18:0-18:2 PE in the hot processing process, its unsaturated fatty acids will degrade to form a variety of odor active compounds. 18:0-18:2 PE can be applied in food processing and research on phospholipid metabolism-related diseases .
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Cat. No.: HY-P10053
CAS No.: 236394-37-9
Target:  

Phospholipase

Research Areas:  

Metabolic Disease

sPLA2-IIA Inhibitor is a cyclic pentapeptide analog of FLSYK (cyclic 2-Nal-Leu-Ser-2-Nal-Arg (c2)), that binds to hGIIA (human IIA phospholipase A2) and inhibits its hydrolytic ability. sPLA2 is a member of the esterase superfamily that catalyzes the hydrolysis of the ester bond at the sn-2 position of glycerophospholipids, releasing free fatty acids such as arachidonic acid and lysophospholipids .
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Cat. No.: HY-145384
CAS No.: 1048660-43-0
Purity:  99.48%
Target:  

Phospholipase

Research Areas:  

Inflammation/Immunology

ROC-0929 (compound 13a) is a potent and selective inhibitor of secreted phospholipases A2 (sPLA2s) with an IC50 of 80 nM, specially targeting hGX. ROC-0929 inhibits the phosphorylation of ERK1/2 and p-38. Secreted phospholipases A2 (sPLA2s) are a family of disulfide-rich, Ca 2+-dependent enzymes that hydrolyze the sn-2 position of glycero-phospholipids to release a fatty acid and a lysophospholipid. ROC-0929 has the potential for researching inflammation related diseases .
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Cat. No.: HY-W783247
CAS No.: 2389048-50-2
Category:  

Lipids

18:1(n7)-16:0 PC-IsoPure is an isomerically pure mixed-acyl glycerophospholipid.
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Cat. No.: HY-157622
CAS No.: 159701-21-0
Research Areas:  

Others

1-Palmitoyl-2-linoleoyl-sn-glycero-3-phosphocholine is a glycerophospholipid with activity for studying the effects of phosphatidylcholine (PC) on the lubrication of damaged mesothelial cells. 1-Palmitoyl-2-linoleoyl-sn-glycero-3-phosphocholine can be used to explore the function and repair mechanism of cell membranes. 1-Palmitoyl-2-linoleoyl-sn-glycero-3-phosphocholine has important application potential in biomedical research.
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Cat. No.: HY-W923483
CAS No.: 95403-34-2
Synonyms: 1-O-Hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine
C16-18:1 PC (1-O-Hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine), also known as 1-O-hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine (HOPC), is a member of the platelet-activating factor (PAF) family of glycerophospholipids and serves as a pro-inflammatory lipid mediator with diverse biological and pharmacological effects; it features a mono-ether structure with an oleoyl chain (18:1) ester-linked at the sn-2 position and a hexadecyl chain (16:0) ether-linked at the sn-1 position.
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Cat. No.: HY-W009194
CAS No.: 65291-30-7
Target:  

Drug Intermediate

Research Areas:  

Infection

(R)-(+)-Trityl glycidyl ether, a heterocyclic compound, is a precursor that can be used to synthesize glycerophospholipids, as well as compounds with antiviral and antimalarial activities .
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Cat. No.: HY-157716
CAS No.: 2260795-76-2
Research Areas:  

Others

08:0 PI ammonium is a glycerophospholipid with a head group carrying a cyclohexanol moiety.
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Cat. No.: HY-W783249
CAS No.: 118139-93-8
Research Areas:  

Others

20:4-16:0 PC-IsoPure is an isomerically pure mixed-acyl glycerophospholipid.
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