granulocyte-colony stimulating factor

By Targets:	c-Fms (3) Endogenous Metabolite (1) Interleukin Related (1) JAK (1) Parasite (1) STAT (2) TRP Channel (1)
By Research Areas:	Cancer (3) Infection (1) Inflammation/Immunology (6) Metabolic Disease (1)

Targets Recommended: TSH Receptor c-Fms

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N3018

Isomaltose 6-O-α-D-Glucopyranosyl-D-glucose; D-Isomaltose	Endogenous Metabolite Parasite	Infection Metabolic Disease
Isomaltose (6-O-α-D-Glucopyranosyl-D-glucose) is a glucose disaccharide. Isomaltose induces G-CSF secretion via heat-induced oxidative polymerization of glucose groups into high-molecular-weight compounds. Isomaltose modulates cecal bacterial cluster structure in mice. Isomaltose exhibits low glycemic index, slow hydrolysis, and prebiotic properties. Isomaltose reduces in vivo Cryptosporidium parvum colonization in neonatal mice. Isomaltose can be used for the research of Cryptosporidium parvum infection .

HY-P99440

Anumigilimab CSL-324	c-Fms JAK STAT	Inflammation/Immunology
Anumigilimab (CSL-324) is an human IgG4 mAb against human granulocyte colony-stimulating factor (G-CSF) receptor. Anumigilimab can be used for increasing numbers of neutrophils at sites of inflammation .

HY-P99879

Efbemalenograstim alfa Benegrastim; Bineuta; F 627	STAT	Inflammation/Immunology
Efbemalenograstim alfa (F 627) is a recombinant fusion protein. Efbemalenograstim alfa is a long acting dimeric granulocyte colony-stimulating factor (G-CSF) that contains two human G-CSF fused to a human immunoglobulin G2 (hIgG2)-Fc fragment with a peptide linker. Efbemalenograstim alfa induces the production of white blood cells .

HY-176464

GSK2220691	TRP Channel	Inflammation/Immunology
SK2220691 is a potent TRPV4 inhibitor. SK2220691 inhibits pulmonary edema induced by GSK1016790. SK2220691 inhibits HCl-induced increases in key factors such as VEGF, keratinocyte-derived chemokine (KC; CXCL1), and granulocyte colony-stimulating factor (GCSF) .

HY-P99913

Eflapegrastim	c-Fms	Inflammation/Immunology Cancer
Eflapegrastim is a composite protein consisting of a genetically modified granulocyte-colony stimulating factor (GCSF) molecule linked via a chemical bond to an IgG4 Fc fragment (LAPS-carrier). Eflapegrastim targets to G-CSF receptor (c-Fms). Eflapegrastim stimulates proliferation and differentiation of neutrophil progenitor cells and maintains stable numbers of mature and functional neutrophils. Eflapegrastim also shortens the duration of neutropenia .

HY-178714

JNJ627	Interleukin Related	Inflammation/Immunology
JNJ627 is a small molecule allosteric inhibitor of IL-17A with a K_D of 92 nM. JNJ627 effectively inhibits the binding of IL-17A and IL-17RA, with an IC₅₀ value of 16 nM. JNJ627 is capable of inhibiting the secretion of G-CSF (granulocyte colony-stimulating factor) caused by IL-17A stimulation. JNJ627 can be used for the study of autoimmune diseases (such as psoriasis) .

HY-P99458

Balugrastim CG 10639	c-Fms	Cancer
Balugrastim (CG 10639) is a novel long-acting recombinant granulocyte colony-stimulating factor (G-CSF) obtained by means of a genetic fusion between recombinant human serum albumin and granulocyte colony-stimulating factor. Balugrastim can be used for the research of breast cancer .

HY-100307

SB 247464	Others	Others
SB 247464 is an orally active nonpeptidyl ligand. SB 247464 can selectively activate the murine granulocyte colony-stimulating factor (G-CSF) signaling pathway and mimic the biological functions of G-CSF. SB 247464 can be used for the study of neutropenia and other diseases .

Cat. No.	Product Name	Target	Research Area	Image

HY-P99440

Anumigilimab CSL-324	c-Fms JAK STAT	Inflammation/Immunology
Anumigilimab (CSL-324) is an human IgG4 mAb against human granulocyte colony-stimulating factor (G-CSF) receptor. Anumigilimab can be used for increasing numbers of neutrophils at sites of inflammation .

HY-P99879

Efbemalenograstim alfa Benegrastim; Bineuta; F 627	STAT	Inflammation/Immunology
Efbemalenograstim alfa (F 627) is a recombinant fusion protein. Efbemalenograstim alfa is a long acting dimeric granulocyte colony-stimulating factor (G-CSF) that contains two human G-CSF fused to a human immunoglobulin G2 (hIgG2)-Fc fragment with a peptide linker. Efbemalenograstim alfa induces the production of white blood cells .

HY-P99913

Eflapegrastim	c-Fms	Inflammation/Immunology Cancer
Eflapegrastim is a composite protein consisting of a genetically modified granulocyte-colony stimulating factor (GCSF) molecule linked via a chemical bond to an IgG4 Fc fragment (LAPS-carrier). Eflapegrastim targets to G-CSF receptor (c-Fms). Eflapegrastim stimulates proliferation and differentiation of neutrophil progenitor cells and maintains stable numbers of mature and functional neutrophils. Eflapegrastim also shortens the duration of neutropenia .

HY-P99458

Balugrastim CG 10639	c-Fms	Cancer
Balugrastim (CG 10639) is a novel long-acting recombinant granulocyte colony-stimulating factor (G-CSF) obtained by means of a genetic fusion between recombinant human serum albumin and granulocyte colony-stimulating factor. Balugrastim can be used for the research of breast cancer .

HY-P990963

Albipagrastim alfa	Inhibitory Antibodies	Inflammation/Immunology Cancer
Albipagrastim alfa is a long-acting granulocyte colony-stimulating factor (G-CSF), which is formed by the fusion of highly active recombinant G-CSF and human serum albumin (HSA). Albipagrastim alfa can significantly inhibit the clearance pathway mediated by the G-CSF receptor. Albipagrastim alfa can be used in tumor-related research .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N3018

Isomaltose 6-O-α-D-Glucopyranosyl-D-glucose; D-Isomaltose	Structural Classification Human Gut Microbiota Metabolites Polysaccharides Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Saccharides Source Classification	Endogenous Metabolite Parasite
Isomaltose (6-O-α-D-Glucopyranosyl-D-glucose) is a glucose disaccharide. Isomaltose induces G-CSF secretion via heat-induced oxidative polymerization of glucose groups into high-molecular-weight compounds. Isomaltose modulates cecal bacterial cluster structure in mice. Isomaltose exhibits low glycemic index, slow hydrolysis, and prebiotic properties. Isomaltose reduces in vivo Cryptosporidium parvum colonization in neonatal mice. Isomaltose can be used for the research of Cryptosporidium parvum infection .

Species:	Human (9) Rhesus Macaque (1) Rat (1) Mouse (3)
Tag:	His (6) Tag Free (6) Avi (1) Flag (1) Fc (2)
Source:	HEK293 (8) CHO (2) E. coli (4)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P71877

	CSF3 Protein, Rhesus macaque granulocyte colony-stimulating factor; CSF3	Rhesus Macaque	E. coli
	CSF3 Protein, a member of the IL-6 superfamily, is a vital granulocyte/macrophage colony-stimulating factor influencing hematopoiesis. It regulates the production, differentiation, and function of granulocytes and monocytes-macrophages, playing a key role in the intricate balance of hematopoietic processes. CSF3's significance within the IL-6 superfamily extends to orchestrating immune system components for optimal functionality. CSF3 Protein, Rhesus macaque is the recombinant Rhesus Macaque-derived CSF3 protein, expressed by E. coli , with tag free.

HY-P70554

	G-CSF Protein, Mouse (HEK293, His) 1 Publications Verification granulocyte colony-stimulating factor; Csf3; G-CSF	Mouse	HEK293
	The G-CSF Protein, a monomeric cytokine in the granulocyte/macrophage colony-stimulating factor family, crucially regulates hematopoiesis by orchestrating the production, differentiation, and function of granulocytes and monocytes-macrophages. Its production emphasizes its significance in maintaining immune system balance and functionality. G-CSF Protein, Mouse (HEK293, His) is the recombinant mouse-derived G-CSF protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P73073

	G-CSF Protein, Human (HEK293, Fc) 1 Publications Verification granulocyte colony-stimulating factor; G-CSF; CSF3; C17orf33	Human	HEK293
	G-CSF, a pivotal cytokine, regulates hematopoiesis by controlling the production, differentiation, and function of granulocytes and monocytes-macrophages. This monomeric protein specifically promotes granulocyte development, playing a crucial role in immune system regulation and blood cell formation. G-CSF Protein, Human (HEK293, Fc) is the recombinant human-derived G-CSF protein, expressed by HEK293 , with N-hFc labeled tag.

HY-P70422

	G-CSF Protein, Human 1 Publications Verification granulocyte colony-stimulating factor; G-CSF; Pluripoietin; Filgrastim; Lenograstim; CSF3; C17orf33; GCSF	Human	E. coli
	Granulocyte colony-stimulating factor (G-CSF) is a glycoprotein secreted by the cells of the immune system, fibroblasts and endothelium, which acts as a hematopoietic and endothelial precursor cells cytokine. G-CSF stimulates maturation of progenitor cells in the bone marrow into differentiated granulocytes, macrophages and the T cells. G-CSF also shows to convey neuroprotection to central neurons upon increases in phosphorylation of PI3K/Akt pathway and regulates epithelial to mesenchymal transition in cancer. G-CSF Protein (Human) is a recombinant protein with tag free that consists of 200 or 204 amino acids, which is expressed in E. coli.

HY-P75692

	G-CSFR/CD114 Protein, Human (HEK293) granulocyte colony-stimulating factor receptor; G-CSF-R; CD114; CSF3R; GCSFR	Human	HEK293
	The G-CSFR/CD114 protein, as a receptor for granulocyte colony-stimulating factor (CSF3), is essential for granulocyte maturation and plays a key role in the proliferation, differentiation, and survival of neutrophil lineage cells. Furthermore, it may be involved in cell surface adhesion or recognition events. G-CSFR/CD114 Protein, Human (HEK293) is the recombinant human-derived G-CSFR/CD114 protein, expressed by HEK293 , with tag free.

HY-P700528

	G-CSFR/CD114 Protein, Human (HEK293, His-Flag) colony stimulating factor 3 receptor (granulocyte); CD114; granulocyte colony-stimulating factor receptor; GCSFR; G-CSF-R; CD114 antigen; G-CSF receptor	Human	HEK293
	The G-CSFR/CD114 protein, as a receptor for granulocyte colony-stimulating factor (CSF3), is essential for granulocyte maturation and plays a key role in the proliferation, differentiation, and survival of neutrophil lineage cells. Furthermore, it may be involved in cell surface adhesion or recognition events. G-CSFR/CD114 Protein, Human (HEK293, His-Flag) is the recombinant human-derived G-CSFR/CD114 protein, expressed by HEK293 , with C-6*His, C-Flag labeled tag.

HY-P72634

	G-CSFR/CD114 Protein, Human (HEK293, Fc) granulocyte colony-stimulating factor receptor; G-CSF-R; CD114; CSF3R; GCSFR	Human	HEK293
	The G-CSFR/CD114 protein, as a receptor for granulocyte colony-stimulating factor (CSF3), is essential for granulocyte maturation and plays a key role in the proliferation, differentiation, and survival of neutrophil lineage cells. Furthermore, it may be involved in cell surface adhesion or recognition events. G-CSFR/CD114 Protein, Human (HEK293, Fc) is the recombinant human-derived G-CSFR/CD114 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P75694

	G-CSFR/CD114 Protein, Human (HEK293, His) granulocyte colony-stimulating factor receptor; G-CSF-R; CD114; CSF3R; GCSFR	Human	HEK293
	The G-CSFR/CD114 protein, as a receptor for granulocyte colony-stimulating factor (CSF3), is essential for granulocyte maturation and plays a key role in the proliferation, differentiation, and survival of neutrophil lineage cells. Furthermore, it may be involved in cell surface adhesion or recognition events. G-CSFR/CD114 Protein, Human (HEK293, His) is the recombinant human-derived G-CSFR/CD114 protein, expressed by HEK293 , with C-His labeled tag.

HY-P705215

	G-CSFR/CD114 Protein, Human (Biotinylated, HEK293, His-Avi) granulocyte colony-stimulating factor receptor; G-CSF-R; CD114; CSF3R; GCSFR	Human	HEK293

HY-P7093A

	G-CSF Protein, Rat (HEK293) 1 Publications Verification rRtG-CSF; CSF-3; MGI-1G; Pluripoietin; Molgramostin; Sargramostim	Rat	HEK293
	G-CSF Protein, Rat (HEK293) is a glycoprotein, acting to stimulate granulopoiesis, the innate immunity, and the differentiation of neural progenitor cells.

HY-P700083AF

	Animal-Free G-CSF Protein, Human (His) 1 Publications Verification CSF-3; MGI-1G; GM-CSF beta; pluripoietin	Human	E. coli
	G-CSF, a pivotal cytokine, regulates hematopoiesis by controlling the production, differentiation, and function of granulocytes and monocytes-macrophages. This monomeric protein specifically promotes granulocyte development, playing a crucial role in immune system regulation and blood cell formation. Animal-Free G-CSF Protein, Human (His) is the recombinant human-derived animal-FreeG-CSF protein, expressed by E. coli , with N-His labeled tag. This product is for cell culture use only.

HY-P7015A

	G-CSF Protein, Human (CHO) rHuG-CSF; CSF-3; MGI-1G; Pluripoietin; Molgramostin; Sargramostim	Human	CHO
	G-CSF Protein, Human (CHO) is a polypeptide growth factor that regulates the production of neutrophilic granulocytes.

HY-P700178AF

	Animal-Free G-CSF Protein, Mouse (His) rMuG-CSF; CSF-3; MGI-1G; Pluripoietin; Molgramostin; Sargramostim	Mouse	E. coli
	The G-CSF Protein, a monomeric cytokine in the granulocyte/macrophage colony-stimulating factor family, crucially regulates hematopoiesis by orchestrating the production, differentiation, and function of granulocytes and monocytes-macrophages. Its production emphasizes its significance in maintaining immune system balance and functionality. Animal-Free G-CSF Protein, Mouse (His) is the recombinant mouse-derived animal-FreeG-CSF protein, expressed by E. coli , with N-His labeled tag. This product is for cell culture use only.

HY-P7068

	G-CSF Protein, Mouse (CHO) 1 Publications Verification rMuG-CSF; CSF-3; MGI-1G; Pluripoietin; Molgramostin; Sargramostim	Mouse	CHO
	G-CSF Protein, Mouse (CHO) is a polypeptide growth factor that regulates the production of neutrophilic granulocytes.

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Host:	Mouse (2) Rabbit (1)
Reactivity:	Human (3) Mouse (2)
Application:	IHC-P (2) IF-Tissue (2) IHC-F (2) WB (3) FC (1)
Isotype:	IgG (3)
Conjugation:	Non-conjugated (3) Biotin (1)
Clonality:	Monoclonal (2) Recombinant (1)
Modification:	Unmodified (2)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P86710

	G-CSF Antibody (YA6402) GCSF; colony stimulating factor 3(granulocyte); CSF 3; CSF beta; CSF3; Csfg; Filgrastim; GCSA; granulocyte colony stimulating factor; Lenograstim; Macrophage granulocyte inducer 2; MGC45931; MGI 2; Pluripoietin; granulocyte colony stimulating factors 3; CSF3_HUMAN.	WB, IHC-P, IHC-F, IF-Tissue	Human, Mouse
	G-CSF Antibody (YA6402) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to G-CSF.

HY-P86710A

	G-CSF Antibody (YA6402)(PBS only) GCSF; colony stimulating factor 3(granulocyte); CSF 3; CSF beta; CSF3; Csfg; Filgrastim; GCSA; granulocyte colony stimulating factor; Lenograstim; Macrophage granulocyte inducer 2; MGC45931; MGI 2; Pluripoietin; granulocyte colony stimulating factors 3; CSF3_HUMAN.	WB, IHC-P, IHC-F, IF-Tissue	Human, Mouse
	G-CSF Antibody (YA6402) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to G-CSF.

HY-P83628

	G-CSF Receptor Antibody (YA3373) CD 114 antibody; CD114 antibody; CD114 antigen antibody; colony stimulating factor 3 receptor (granulocyte) antibody; colony stimulating factor 3 receptor antibody; CSF 3R antibody; CSF3R antibody; CSF3R_HUMAN antibody; Csfgr antibody; G CSF R antibody; G-CSF receptor antibody; G-CSF-R antibody; GCSFR antibody; granulocyte colony stimulating factor receptor antibody; granulocyte colony-stimulating factor receptor antibody; OTTHUMP00000009703 antibody; OTTHUMP00000009704 antibody; OTTHUMP00000009705 antibody	WB, FC	Human
	G-CSF Receptor Antibody (YA3373) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to G-CSF Receptor.

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granulocyte-colony stimulating factor

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