1 Result for "

hCAIX/XII-IN-13

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "hCAIX/XII-IN-13" in MCE Product Catalog:

Cat. No.: HY-162000
Target:  

Apoptosis

Research Areas:  

Cancer

hCAIX/XII-IN-13 is an inhibitor of human carbonic anhydrases (hCA). hCAIX/XII-IN-13 shows good inhibitory activity against the tumor-related CA subtypes IX and XII, with Ki values of 0.08 µM and 0.06 µM, respectively. Under hypoxic conditions, hCAIX/XII-IN-13 can restore the cytotoxicity of Doxorubicin (HY-15142A) on MCF-7 cells, increasing G2/M phase cell cycle arrest and apoptosis .
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