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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
human PREP
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "human PREP" in MCE Product Catalog:
Art. -Nr.: HY-RS11083
Target:
Forschungsgebiete:
PREP Human Pre-designed siRNA Set A contains three designed siRNAs for PREP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-E71016
Target:
Forschungsgebiete:
Proline specific endopeptidase, Flavobacterium sp. (EC 3.4.21.26) is an enzyme that in humans is encoded by the PREP gene.
Art. -Nr.: HY-P703584
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PREP; PEP; Prolyl Endopeptidase; PE; Post-Proline Cleaving Enzyme; DJ355L5.1 (Prolyl Endopeptidase); Prolyl Oligopeptidase
Species:
Human
Source:
E. coli
Art. -Nr.: HY-106021
CAS. Nr.: 192658-64-3
Synonyms: ILX651 free base
Forschungsgebiete:
Tasidotin (ILX651 free base) is a tubulin inhibitor and competitive Prolyl Endopeptidase (PREP) inhibitor, with an IC50 of 10 μM against bovine tubulin. Tasidotin exhibits high cerebrospinal fluid penetration in non-human primates. Tasidotin antagonizes microtubule assembly and induces an extended assembly lag phase, thereby inhibiting mitosis and cell proliferation, and exerts cytotoxic and oncolytic effects on cancer cells. Tasidotin is metabolized into polypeptides and proline inside cells, and its in vivo metabolism is mediated by prolyl endopeptidase. Tasidotin can be applied in research related to Burkitt's lymphoma, breast cancer, leukemia, melanoma, central nervous system malignancies and various solid tumors .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
