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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
38 Results for "
hydrogen sulfide
" in MedChemExpress (MCE) Product Catalog:
Products (38)
38 Results for "hydrogen sulfide" in MCE Product Catalog:
13
13 Publications Verification
Synonyms: N-Acetylcysteine ethyl ester; NACET
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N-Acetyl-L-cysteine ethyl ester is an esterified form of N-acetyl-L-cysteine (NAC). N-Acetyl-L-cysteine ethyl ester exhibits enhanced cell permeability, and produce NAC and cysteine. N-Acetyl-L-cysteine ethyl ester increases circulating hydrogen sulfide (H2S) and can be used as an H2S producer. N-Acetyl-L-cysteine ethyl ester has the potential to substitute NAC as a mucolytic agent, and as a GSH-related antioxidant .
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6 Cited Publications
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AP39 is a triphenylphosphonium derivatised anethole dithiolethione and mitochondria-targeting hydrogen sulfide (H2S) donor. AP39 increases intracellular H2S levels. AP39 exerts cytoprotective effects and maintains mitochondrial DNA integrity under oxidative stress conditions. AP39 protects against myocardial reperfusion injury in mice model and has the potential for Alzheimer's disease research .
5
5 Cited Publications
Synonyms: 5-(4-Hydroxyphenyl)-3H-1,2-dithiole-3-thione; ACS 1
ADT-OH is a hydrogen sulfide-releasing donor. ADT-OH induces apoptosis and upregulates FADD. ADT-OH inhibits FAK/Paxillin. ADT-OH has the potential for the research of cancer diseases .
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2 Cited Publications
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7-Azido-4-methylcoumarin is a selective coumarin-based fluorescent probe for hydrogen sulfide (H2S). In the presence of H2S, the aromatic azido group of 7-Azido-4-methylcoumarin is selectively reduced to produce the fluorescently active 7-amino-4-methylcoumarin (AMC). 7-Azido-4-methylcoumarin binds to the coumarin/phenol-binding site of BSA, the aglycone-binding site of UGT1A6, and the substrate-binding site of SULT1A1, respectively. 7-Azido-4-methylcoumarin retains its fluorescent properties after covalent binding, acts as a fluorescent H2S probe, and does not react with cysteine, homocysteine or glutathione (Ex/Em = 340/445 nm) .
1
1 Cited Publications
Cat. No.: HY-W015635
CAS No.: 2179-57-9
1
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other families Other Alkaloids Other Diseases Glucosinolates Plants Disease Research Fields
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1
1 Cited Publications
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FW1256 is a phenyl analogue and a slow-releasing hydrogen sulfide (H2S) donor. FW1256 inhibits NF-κB activity and induces cell apoptosis. FW1256 exerts potent anti-inflammatory effects and has the potential for cancer and cardiovascular disease treatment .
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Sodium tetraborate decahydrate is an orally active biochemical reagent and antibacterial agent. Sodium tetraborate decahydrate leads to an increase in the activity of Catalase, Superoxide dismutase. Sodium tetraborate decahydrate reduces Hydrogen sulfide and the sulfate-reducing bacteria population of swine manure. Sodium tetraborate decahydrate serves as flame suppressant for wood cellulose. Sodium tetraborate decahydrate is a triglyceride transesterification catalyst. Sodium tetraborate decahydrate suppresses the formation of chlorinated by-products in Cl −-containing water. Sodium tetraborate decahydrate has a neuroprotective effect against chromium poisoning. Sodium tetraborate decahydrate can protect the heart from chromium damage at low doses. Sodium tetraborate in a low dose with an isolated application shows an antioxidant effect .
Cat. No.: HY-W024271
CAS No.: 63149-33-7
Synonyms: 9-Formyl-8-hydroxyjulolidine
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8-Hydroxyjulolidine-9-carboxaldehyde (9-Formyl-8-hydroxyjulolidine) is a highly selective fluorescent probe for hydrogen sulfide (S 2−) and silicate (SiO3 2−). 8-Hydroxyjulolidine-9-carboxaldehyde operates via a mechanism of blocking intramolecular charge transfer (ICT), exhibiting significant fluorescence enhancement in the presence of weak acid ions. 8-Hydroxyjulolidine-9-carboxaldehyde is promising for research of fluorescence imaging of hydrogen sulfide within living cells .
Cat. No.: HY-106784A
CAS No.: 92284-99-6
Cat. No.: HY-174790
Firefly Luciferase mRNA is a reporter mRNA that can be transfected into cells to express firefly luciferase protein. Firefly Luciferase mRNA induces cytotoxicity in cancer cells at low concentrations. In cancer cells, the expression level of luciferase shows a non-linear relationship with the dose of Firefly Luciferase mRNA. When combined with the H2S-responsive bioluminescent probe (H-Luc), Firefly Luciferase mRNA enables bioluminescence-based detection of endogenous hydrogen sulfide in non-transgenic NAFLD cell models and NAFLD mouse models. Firefly Luciferase mRNA can be used in studies related to non-alcoholic fatty liver disease .
Cat. No.: HY-D1275
CAS No.: 2119597-33-8
Cat. No.: HY-169331
H2S scavenger 1 triflate is a selective H2S scavenger and antibacterial adjuvant. H2S scavenger 1 triflate consumes hydrogen sulfide produced by H2S-producing bacteria via chemical scavenging, and does not act on H2S synthases. H2S scavenger 1 triflate enhances the clearance of H2S-producing bacteria mediated by macrophages and polymorphonuclear neutrophils. H2S scavenger 1 triflate inhibits the biofilm formation of H2S-producing bacteria and eliminates pre-formed biofilms. H2S scavenger 1 triflate can be used for the research of Pseudomonas aeruginosa-infected pneumonia and Pseudomonas aeruginosa-infected skin wounds .
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Cystathionine β-synthase is an enzyme that catalyzes the condensation of serine and homocysteine to water and cystathionine. Cystathionine β-synthase is a prominent enzyme for the production of hydrogen sulfide (H2S) .
Cat. No.: HY-P2995B
Cat. No.: HY-20794
CAS No.: 41175-50-2
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8-Hydroxyjulolidine is a chromophore moiety of a fluorescent probe for the detection of weak acid ions. 8-Hydroxyjulolidine can be used to synthesize the salicylaldehyde derivative 9-formyl-8-hydroxyjulolidine, which exhibits sensitive detection ability to pH changes of hydrogen sulfide and silicate in aqueous solution .
Cat. No.: HY-D2476
CAS No.: 433254-36-5
Cat. No.: HY-150038
CAS No.: 1357362-67-4
Synonyms: NBS-1120
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NOSH-aspirin (NBS-1120) is an orally active hybrid molecule that releases nitric oxide and hydrogen sulfide. NOSH-aspirin inhibits pancreatic cancer cell proliferation and induces apoptosis. NOSH-aspirin inhibits cancer cell growth and suppresses NF-κB and FoxM1 in a mouse model of pancreatic cancer. NOSH-aspirin also alleviates motor deficits and dopaminergic neuron degeneration in a rat model of Parkinson's disease. NOSH-aspirin reduces neuroinflammation caused by microglial and astrocytic activation. NOSH-aspirin can be used in research on cancers such as pancreatic cancer and neurological diseases such as Parkinson's disease .
Cat. No.: HY-161815
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Anti-inflammatory agent 89 is a multi-target glucocorticoid-isothiocyanate hybrid with anti-inflammatory activity. Anti-inflammatory agent 89 releases hydrogen sulfide via its isothiocyanate group, inhibits antigen-induced mast cell degranulation, alleviates pulmonary inflammation, and suppresses bronchial hyperresponsiveness and airway fibrosis. Anti-inflammatory agent 89 can be used in asthma research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
