Glucotropaeolin potassium
Based on 1 publication(s) in Google Scholar
Glucotropaeolin (Benzylglucosinolate) potassium is an orally effective glucosinolate that can be extracted from cruciferous vegetables. Glucotropaeolin potassium exhibits activities including moderate reduction of spontaneous DNA damage in animals, anti-inflammation, antimicrobial action, and anticancer effect. Glucotropaeolin potassium can be used in research related to tendinopathy, late blight, type 2 diabetes, and cancer.
For research use only. We do not sell to patients.
- Purity: 99.40%
- CAS No.: 5115-71-9
- Formula: C14H18KNO9S2
- Molecular Weight:447.52
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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HY-N4321R
Glucotropaeolin potassium (Standard) -
HY-N0404
Sinigrin -
HY-12290
Arg-Gly-Asp-Ser -
HY-N0404R
Sinigrin (Standard) -
![Galβ(1-3)[Neu5Acα(2-6)]GalNAc-α-pNP](https://file.medchemexpress.com/product_pic/hy-w145540.gif)
HY-W145540
Galβ(1-3)[Neu5Acα(2-6)]GalNAc-α-pNP -
HY-12290R
Arg-Gly-Asp-Ser (Standard) -
HY-W102386
Methyl 2,3,4,6-Tetra-O-acetyl-1-thio-α-D-mannopyranoside -
HY-W145526
Methyl 2,3,4-tri-O-benzyl-1-thio-β-L-fucopyranoside
Publications Citing Use of MedChemExpress (MCE) Glucotropaeolin potassium
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Biological Activity
Description
In Vitro
Glucotropaeolin (1 mM; 25 min) releases H2S in a cysteine-dependent manner, reaching a final concentration of 0.74 μM over 25 minutes in a cell-free system[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
Potassium glucotropaeolin (30 µmol/mL, 50 µL per dose; p.i.; once daily; consecutive treatment for 9 days) alleviates spontaneous pain but fails to prevent mechanical hyperalgesia and exercise-induced pain exacerbation in a rat tendinopathy model induced by Collagenase type I[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Sprague-Dawley (male, 220-250 g, tendinopathy induced via intratendinous collagenase type I injection)[1]
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Dosage:1, 10, 30, 100 µmol/kg
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Administration:o.p.; single dose; for 7 days
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Result:Dose-dependently increased the mechanical pain threshold and alleviate spontaneous pain.
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Animal Model:Sprague-Dawley (male, 220-250 g, tendinopathy induced via intratendinous collagenase type I injection)[1]
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Dosage:30 µmol/mL, 50 µL/rat
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Administration:p.i.; once daily; 9 consecutive days
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Result:Alleviated spontaneous pain but failed to prevent mechanical hyperalgesia and movement-induced exacerbation of pain.
Chemical Information
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CAS No. 5115-71-9
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Appearance Solid
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Molecular Weight 447.52
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Formula C14H18KNO9S2
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Color White to off-white
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SMILES
O=S(O/N=C(CC1=CC=CC=C1)/S[C@@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)CO)(O[K])=O
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Synonyms
Benzylglucosinolate potassium
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (1)
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Journal Impact Factor
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Most Recent
Solvent & Solubility
In Vitro:
H2O : ≥ 100 mg/mL (223.45 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (292 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 2.2345 mL | 11.1727 mL | 22.3454 mL | 55.8634 mL |
| 5 mM | 0.4469 mL | 2.2345 mL | 4.4691 mL | 11.1727 mL | |
| 10 mM | 0.2235 mL | 1.1173 mL | 2.2345 mL | 5.5863 mL | |
| 15 mM | 0.1490 mL | 0.7448 mL | 1.4897 mL | 3.7242 mL | |
| 20 mM | 0.1117 mL | 0.5586 mL | 1.1173 mL | 2.7932 mL | |
| 25 mM | 0.0894 mL | 0.4469 mL | 0.8938 mL | 2.2345 mL | |
| 30 mM | 0.0745 mL | 0.3724 mL | 0.7448 mL | 1.8621 mL | |
| 40 mM | 0.0559 mL | 0.2793 mL | 0.5586 mL | 1.3966 mL | |
| 50 mM | 0.0447 mL | 0.2235 mL | 0.4469 mL | 1.1173 mL | |
| 60 mM | 0.0372 mL | 0.1862 mL | 0.3724 mL | 0.9311 mL | |
| 80 mM | 0.0279 mL | 0.1397 mL | 0.2793 mL | 0.6983 mL | |
| 100 mM | 0.0223 mL | 0.1117 mL | 0.2235 mL | 0.5586 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Glucotropaeolin potassium Related Classifications
HY-N4321 Related Classifications
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