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Results for "

incognita

" in MedChemExpress (MCE) Product Catalog:

15

Inhibitors & Agonists

1

Peptides

8

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-119459
    Fluopyram
    1 Publications Verification

    		 Environmental Pollutants Constitutive Androstane Receptor Parasite Caspase Fungal NF-κB Succinate Dehydrogenase Pregnane X Receptor (PXR) Infection Cancer
    Fluopyram is an orally active succinate dehydrogenase inhibitor, antifungal and nematicide. Fluopyram inhibits succinate dehydrogenase activity, activates CAR/PXR nuclear receptors, and increases caspase-3, TNF-α and NF-κB. Fluopyram inhibits the growth of F. virguliforme, Botrytis cinerea and Alternaria solani with EC50 values of 3.35, 5.389 and 0.244 µg/mL, respectively. Fluopyram induces liver and thyroid tumor formation. Fluopyram is nephrotoxic and embryotoxic .
    Fluopyram
  • HY-N9599
    Roridin A

    		Fungal Endogenous Metabolite Parasite Insecticide Infection
    Roridin A acts as an inhibitor of pollen development in Arabidopsis thaliana and nematicide. Roridin A is isolated from the fungus Cylindrocarpon sp. Roridin A delays the flowering time of Arabidopsis thaliana, inhibits pollen development and stem elongation, and blocks plant growth. Roridin A induces larval death of the southern root-knot nematode (Meloidogyne incognita) .
    Roridin A
  • HY-W753375
    Fluindapyr

    		Environmental Pollutants Fungal Succinate Dehydrogenase Infection
    Fluindapyr is a broad-spectrum pyrazolamide chiral fungicide of succinate dehydrogenase inhibitor (SDHIs) with broad bactericidal spectrum and good efficacy. Fluopimomide is effective against M. incognita in vitro and application of fuopimomide shows some growth promotion effect in cucumber .
    Fluindapyr
  • HY-N6744
    Chaetoglobosin A

    		Apoptosis Endogenous Metabolite Fungal Parasite Arp2/3 Complex Infection Cancer
    Chaetoglobosin A is a secondary metabolite and nematicide. Chaetoglobosin A is produced by Penicillium aquamarinium. Chaetoglobosin A targets Filamentous actin in cells, thereby inducing cell cycle arrest, and inhibiting membrane ruffle formation and cell migration. Chaetoglobosin A preferentially induces Apoptosis in chronic lymphocytic leukemia cells. Chaetoglobosin A induces dose- and time-dependent death in J2 larvae of the southern root-knot nematode (Meloidogyne incognita). Chaetoglobosin A can be used in studies related to root-knot nematode disease and chronic lymphocytic leukemia .
    Chaetoglobosin A
  • HY-P5957
    Omphalotin A

    		Parasite Infection
    Omphalotin A is a cyclic peptide, and shows nematicidal activity .
    Omphalotin A
  • HY-118448
    2,4-Diacetylphloroglucinol

    		Antibiotic Bacterial Fungal Parasite Infection
    2,4-Diacetylphloroglucinol is a polyketide antibiotic produced by Pseudomonas fluorescens. 2,4-Diacetylphloroglucinol exhibits broad-spectrum toxicity against various organisms such as bacteria, fungi, oomycetes, and nematodes. 2,4-Diacetylphloroglucinol can also inhibit plant pathogens and affect the root development of tomato seedlings .
    2,4-Diacetylphloroglucinol
  • HY-N8392
    Ascr#9

    		Parasite Infection
    Ascr#9 is a small-molecule pheromone belonging to the ascaroside family, and it is widely present in nematodes. Ascr#9 promotes dispersal or elicits avoidance behavior in various nematode species (such as Caenorhabditis elegans and entomopathogenic nematodes), suggesting that individuals evacuate from adverse environments. Ascr#9 exhibits repellent potential in Meloidogyne incognita .
    Ascr#9
  • HY-114373
    Calarene

    		Parasite Infection
    Calarene is an insecticide that can be obtained from the stem of Kadsura heteroclite. Calarene is toxic to Meloidogyne incognita, Sitophilus zeamais, and mosquitoes. Calarene can be used in the research of plant pests and mosquito control .
    Calarene
  • HY-121325
    Fervenulin
    1 Publications Verification

    		 Parasite Infection
    Fervenulin has nematicidal activity and inhibits egg hatch and J2 mortality of M. incognita with MICs of 30 μg/mL and 120 μg/mL, respectively .
    Fervenulin
  • HY-163780
    AChE-IN-66

    		Parasite Infection
    Nematicidal agent 1 is a potent nematicidal agent. Nematicidal agent 1 binds to the pocket of acetylcholine esterase (AChE) .
    AChE-IN-66
  • HY-N15498
    Gibepyrone D

    		Insecticide Infection
    Gibepyrone D is an α-pyrone compound found in Gibberella fujikuroi and the endophytic fungus Fusarium oxysporum 162. Gibepyrone D exhibits significant lethal activity against nematodes with an LC50 value of 134 μg/mL (72 h) against the J2 larvae of Meloidogyne incognita. Gibepyrone D is promising for research of nematicides .
    Gibepyrone D
  • HY-W727209
    Fluazaindolizine

    		Parasite Infection
    Fluazaindolizine is a fluorinated nematicide. Fluazaindolizine induces mortality in second-stage juveniles (J2) of Meloidogyne incognita and Tylenchulus semipenetrans in vitro. Fluazaindolizine impacts plant-parasitic nematode parasitism. Fluazaindolizine can be used for the research of plant-parasitic nematode infestation .
    Fluazaindolizine
  • HY-W102349
    S-Methyl thioacetate

    		Parasite Infection
    S-Methyl thioacetate is a toxicant with fumigant activity, can be found in emissions from Bacillus oshimensis, Burkholderia gladioli, Burkholderia cepacia, and Pseudomonas oryzihabitans. S-Methyl thioacetate exerts fumigant toxicity against Caenorhabditis elegans and root-knot nematode Meloidogyne incognita. S-Methyl thioacetate functions as a bacterial volatile organic compound. S-Methyl thioacetate can be used for the research of plant-parasitic nematode infection .
    S-Methyl thioacetate
  • HY-N18080
    Parthenin

    		Parasite DNA Alkylator/Crosslinker Bacterial Infection Inflammation/Immunology Cancer
    Parthenin is a pseudoguaianolide-type sesquiterpene lactone present in Parthenium hysterophorus L. Parthenin induces chromosomal aberrations, mainly chromatid breaks, in human peripheral blood lymphocytes. Parthenin exhibits toxicity against Salmonella typhimurium and Escherichia coli strains, with reduced toxicity in the presence of a metabolic activation system (S9). Parthenin acts as an antifeedant against the 6th instar larvae of the tobacco cutworm (Spodoptera litura). Parthenin shows insecticidal activity against adult cowpea weevils (Callosobruchus maculatus). Parthenin inhibits seed germination and seedling growth of sicklepod (Cassia tora). Parthenin possesses nematicidal activity against the 2nd instar larvae of the southern root-knot nematode (Meloidogyne incognita). Parthenin serves as a research agent for studies related to cancer, malaria, amoebiasis, inflammatory diseases, and bacterial infections .
    Parthenin
  • HY-183949
    Insecticidal agent 33

    		Insecticide Cholinesterase (ChE) Reactive Oxygen Species (ROS) Infection
    Insecticidal agent 33 is an AChE inhibitor with nematicidal activity. Insecticidal agent 33 impairs locomotor activity of Caenorhabditis elegans, and induces oxidative damage in Caenorhabditis elegans, including elevated reactive oxygen species (ROS) levels, lipofuscin accumulation, lipid deposition, and disrupted cellular homeostasis. Insecticidal agent 33 can be used for the research of plant-parasitic nematode infection .
    Insecticidal agent 33

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