56613-80-0
Chemical Structure
(R)-(-)-2-Phenylglycinol
Synonym(s): D-Phenylglycinol; (-)-Phenylglycinol
- CAS No.: 56613-80-0
- Formula:C8H11NO
- Molecular Weight:137.18
IUPAC Name: (R)-2-amino-2-phenylethan-1-ol
InChIKey: IJXJGQCXFSSHNL-QMMMGPOBSA-N
SMILES: N[C@@H](CO)C1=CC=CC=C1
Biological Activity: (R)-(-)-2-Phenylglycinol (D-Phenylglycinol; (-)-Phenylglycinol) is a chiral β-amino alcohol, a starting material for chiral synthesis, and a potential nematicide. (R)-(-)-2-Phenylglycinol exhibits nematicidal and egg hatching inhibitory activity against the southern root-knot nematode (Meloidogyne incognita), and is also an upregulated metabolite in the fermentation broth of Streptomyces aquilus JXGZ01. (R)-(-)-2-Phenylglycinol can be used as a framework for constructing zwitterionic bicyclic lactams and multi-substituted piperidine/piperidine acid drugs. (R)-(-)-2-Phenylglycinol can be used in drug synthesis and nematode infection-related research[1][2].
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(R)-(-)-2-Phenylglycinol | 98.0% | (R)-(-)-2-Phenylglycinol (D-Phenylglycinol; (-)-Phenylglycinol) is a chiral β-amino alcohol, a starting material for chiral synthesis, and a potential nematicide. (R)-(-)-2-Phenylglycinol exhibits nematicidal and egg hatching inhibitory activity against the southern root-knot nematode (Meloidogyne incognita), and is also an upregulated metabolite in the fermentation broth of Streptomyces aquilus JXGZ01. (R)-(-)-2-Phenylglycinol can be used as a framework for constructing zwitterionic bicyclic lactams and multi-substituted piperidine/piperidine acid drugs. (R)-(-)-2-Phenylglycinol can be used in drug synthesis and nematode infection-related research. | ||||||||||||||||||||
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- [1]. Xu X, et al. Separation and identification of nematicidal active compounds in culture filtrate of Streptomyces aquilus JXGZ01 based on metabolomic analysis. Pest Manag Sci. 2025 Aug;81(8):4590-4600. [Content Brief]
- [2]. Reyes-Bravo E, et al. Diastereoselective synthesis of new zwitterionic bicyclic lactams, scaffolds for construction of 2-substituted-4-hydroxy piperidine and its pipecolic acid derivatives. RSC Adv. 2022 Feb 2;12(7):4187-4190.
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