53 Results for "

interleukin 17A

" in MedChemExpress (MCE) Product Catalog:
Products (53)

53 Results for "interleukin 17A" in MCE Product Catalog:

13
13 Publications Verification
Cat. No.: HY-P9927
CAS No.: 1229022-83-6
Synonyms: AIN457

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology Cancer

Secukinumab (AIN457) is a high affinity, human monoclonal antibody targeted against interleukin (IL)-17A. Secukinumab is the first-in-class anti-IL-17 agent used for the research of plaque psoriasis, ankylosing spondylitis and psoriatic arthritis .
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13
13 Publications Verification
Cat. No.: HY-P9927A
CAS No.: 1229022-83-6

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Secukinumab (Anti-Human IL-17A) is a fully human anti-interleukin-17A monoclonal antibody. Anti-Human IL-17A can be used for research in psoriasis pathogenesis .
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12
12 Cited Publications
Cat. No.: HY-P70527
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL17A; Cytotoxic T-Lymphocyte-Associated Protein 8; Prev. CTLA8; interleukin-17A; Prev. IL17; CTLA-8; IL-17A; interleukin-17; IL-17; ILA17; interleukin 17 (Cytotoxic T-Lymphocyte-Associated Serine Esterase 8); interleukin 17A; Cytotoxic T-Lymphocyte-Assoc
Species:  
Human
Source:  
HEK293
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6
6 Cited Publications
Cat. No.: HY-P7036
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL17A; Cytotoxic T-Lymphocyte-Associated Protein 8; Prev. CTLA8; interleukin-17A; Prev. IL17; CTLA-8; IL-17A; interleukin-17; IL-17; ILA17; interleukin 17 (Cytotoxic T-Lymphocyte-Associated Serine Esterase 8); interleukin 17A; Cytotoxic T-Lymphocyte-Associated Antigen 8
Species:  
Human
Source:  
E. coli
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5
5 Cited Publications
Cat. No.: HY-P70753
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL17A; Cytotoxic T-Lymphocyte-Associated Protein 8; Prev. CTLA8; interleukin-17A; Prev. IL17; CTLA-8; IL-17A; interleukin-17; IL-17; ILA17; interleukin 17 (Cytotoxic T-Lymphocyte-Associated Serine Esterase 8); interleukin 17A; Cytotoxic T-Lymphocyte-Assoc
Species:  
Mouse
Source:  
HEK293
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3
3 Cited Publications
Cat. No.: HY-P9924
CAS No.: 1143503-69-8
Synonyms: LY2439821

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Ixekizumab (LY2439821) is a humanized IgG4 monoclonal antibody that selectively binds and neutralizes interleukin IL-17A (KD<3 pM). Ixekizumab directly blocks IL-17A binding to IL-17RA (IL-17A receptor) but does not bind to other IL-17 family members. Ixekizumab is used for the research of moderate-to-severe plaque psoriasis .
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3
3 Cited Publications
Cat. No.: HY-101913
CAS No.: 2205034-18-8
Purity:  99.74%
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology Cancer

IL-17A antagonist 1 is an interleukin-17A (IL-17A) antagonist with an IC50 of 1.14 μM and a Kd of 0.66 μM. IL-17A antagonist 1 binds specifically and exclusively to the IL-17A homodimer at its central dimer interface pocket, induces a large conformational change that widens the pocket, and disrupts the IL-17A/IL-17RA interaction. IL-17A antagonist 1 does not bind to IL-17F or IL-17RA .
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3
3 Cited Publications
Cat. No.: HY-P79326
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL17A; Cytotoxic T-Lymphocyte-Associated Protein 8; Prev. CTLA8; interleukin-17A; Prev. IL17; CTLA-8; IL-17A; interleukin-17; IL-17; ILA17; interleukin 17 (Cytotoxic T-Lymphocyte-Associated Serine Esterase 8); interleukin 17A; Cytotoxic T-Lymphocyte-Assoc
Species:  
Rat
Source:  
CHO
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3
3 Cited Publications
Cat. No.: HY-P700194AF
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL17A; Cytotoxic T-Lymphocyte-Associated Protein 8; Prev. CTLA8; interleukin-17A; Prev. IL17; CTLA-8; IL-17A; interleukin-17; IL-17; ILA17; interleukin 17 (Cytotoxic T-Lymphocyte-Associated Serine Esterase 8); interleukin 17A; Cytotoxic T-Lymphocyte-Assoc
Species:  
Mouse
Source:  
E. coli
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2
2 Cited Publications
Cat. No.: HY-N3029
CAS No.: 1013-69-0
Noreugenin is a phenolic compound found in Calea uniflora Less. Noreugenin inhibits myeloperoxidase activity and reduces levels of proinflammatory cytokines IL-1β and IL-17A levels in LPS (HY-D1056)-induced murine pleurisy model. Noreugenin reduces apoptosis and necrosis. Noreugenin reduces lipid peroxidation, and antioxidant enzyme (CAT, SOD, GST) activity. Noreugenin exhibits anti-inflammatory and antioxidant effects. Noreugenin can be used for the research of inflammatory conditions, such as pleurisy .
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2
2 Cited Publications
Cat. No.: HY-P81114
Synonyms: interleukin-17A; CTLA-8; CTLA 8; CTLA8; Cytotoxic T lymphocyte associated antigen 8; Cytotoxic T lymphocyte associated serine esterase 8; IL 17A; IL-17A; IL-17; interleukin 17; interleukin-17; interleukin 17A; interleukin17; interleukin17A; IL17_HUMAN; IL17_MOUSE.

Host:  

Rabbit

Application:  

WB, ELISA, IHC-P, IHC-F, ICC/IF

Reactivity:  

Mouse, Rat

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2
2 Cited Publications
Cat. No.: HY-P7372
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL17A; Cytotoxic T-Lymphocyte-Associated Protein 8; Prev. CTLA8; interleukin-17A; Prev. IL17; CTLA-8; IL-17A; interleukin-17; IL-17; ILA17; interleukin 17 (Cytotoxic T-Lymphocyte-Associated Serine Esterase 8); interleukin 17A; Cytotoxic T-Lymphocyte-Assoc
Species:  
Mouse
Source:  
CHO
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2
2 Cited Publications
Cat. No.: HY-P7373
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL17A; Cytotoxic T-Lymphocyte-Associated Protein 8; Prev. CTLA8; interleukin-17A; Prev. IL17; CTLA-8; IL-17A; interleukin-17; IL-17; ILA17; interleukin 17 (Cytotoxic T-Lymphocyte-Associated Serine Esterase 8); interleukin 17A; Cytotoxic T-Lymphocyte-Assoc
Species:  
Human
Source:  
CHO
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1
1 Cited Publications
Cat. No.: HY-P78556
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL17A; Cytotoxic T-Lymphocyte-Associated Protein 8; Prev. CTLA8; interleukin-17A; Prev. IL17; CTLA-8; IL-17A; interleukin-17; IL-17; ILA17; interleukin 17 (Cytotoxic T-Lymphocyte-Associated Serine Esterase 8); interleukin 17A; Cytotoxic T-Lymphocyte-Assoc
Species:  
Rat
Source:  
E. coli
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1
1 Cited Publications
Cat. No.: HY-P73171
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL17A; Cytotoxic T-Lymphocyte-Associated Protein 8; Prev. CTLA8; interleukin-17A; Prev. IL17; CTLA-8; IL-17A; interleukin-17; IL-17; ILA17; interleukin 17 (Cytotoxic T-Lymphocyte-Associated Serine Esterase 8); interleukin 17A; Cytotoxic T-Lymphocyte-Assoc
Species:  
Human
Source:  
CHO
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1
1 Cited Publications
Cat. No.: HY-P73175
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL17A; Cytotoxic T-Lymphocyte-Associated Protein 8; Prev. CTLA8; interleukin-17A; Prev. IL17; CTLA-8; IL-17A; interleukin-17; IL-17; ILA17; interleukin 17 (Cytotoxic T-Lymphocyte-Associated Serine Esterase 8); interleukin 17A; Cytotoxic T-Lymphocyte-Assoc
Species:  
Rabbit
Source:  
E. coli
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Cat. No.: HY-153780
CAS No.: 2467732-66-5
Synonyms: DC-806; LY4100504; S-011806
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Navepdekinra (DC-806) is an orally active, potent interleukin-17A (IL-17A) inhibitor (IC50 = 10.81 nM). Navepdekinra disrupts the IL-17A protein-receptor interaction, suppressing the downstream pro-inflammatory signaling pathway. Navepdekinra inhibits arthritis in a collage-induced arthritis (CIA) rat model. Navepdekinra can be used for psoriasis, psoriatic arthritis, and ankylosing spondylitis .
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Cat. No.: HY-P99335
CAS No.: 1792181-33-9
Synonyms: Anti-Human IL17A Recombinant Antibody; SHR-1314

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Vunakizumab (Anti-Human IL17A Recombinant Antibody) is a recombinant human IgGκ monoclonal antibody and an Interleukin-17A (IL-17A) inhibitor. Vunakizumab binds to IL-17A to inhibit downstream cytokines and block inflammatory signaling. Vunakizumab can be used for the research of chronic plaque psoriasis and ankylosing spondylitis .
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Cat. No.: HY-P99515
CAS No.: 2382921-73-3
Synonyms: GR 1501

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Xeligekimab (GR 1501) is an anti-human interleukin 17A (IL-17A) humanized monoclonal antibody. Xeligekimab inhibits the pro-inflammatory cascade. Xeligekimab can be used for the research of inflammatory disease, such as radiographic axial spondyloarthritis .
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Cat. No.: HY-P3450
CAS No.: 2641313-47-3
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Erepdekinra is an interleukin-17A (IL-17A) receptor antagonist .
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