1 Result for "

isoeugenol-type eugenol analog

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "isoeugenol-type eugenol analog" in MCE Product Catalog:

Methyl isoeugenol
Methyl isoeugenol
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Cat. No.: HY-N2439
CAS No.: 93-16-3
Category:  

Natural Products Neurological Disease Plants Other Families Extract Pteris semipinnata L. Sp. Disease Research Fields

Target:  

Environmental Pollutants Pyroptosis SOD Quinone Reductase Keap1-Nrf2 NF-κB

Methyl isoeugenol is an orally active, blood-brain barrier-permeable isoeugenol-type eugenol analog. Methyl isoeugenol promotes the nuclear translocation of Nrf2, upregulates the expressions of HO-1, NQO1 and SOD, and reduces the expression level of MDA. Methyl isoeugenol decreases the nuclear translocation of NF-κB. Methyl isoeugenol inhibits NLRP3 inflammasome-mediated pyroptosis. Methyl isoeugenol reduces cerebral infarction volume and regulates the M1/M2 phenotypic balance of microglia. Methyl isoeugenol can be used for the research of cerebral ischemia-reperfusion injury .
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