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35 Results for "
lactone metabolite
" in MedChemExpress (MCE) Product Catalog:
Products (35)
35 Results for "lactone metabolite" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-41982
CAS No.: 32449-92-6
Synonyms: D-Glucurono-6,3-lactone; D-Glucurono-γ-lactone; D-Glucuronolactone; Dicurone; Glucoxy; Glucurolactone; Glucurone
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1 Cited Publications
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Cysteine Thiol Probe is a thiol-based probe designed to label electrophilic natural products. Cysteine Thiol Probe possesses each of the characteristics of an ideal pharmacophore probe, and has a chromophore. Cysteine Thiol Probe is capable of engaging enone-, β-lactam-, and β-lactone-based electrophilic metabolites .
Synonyms: Omuralide; β-Clastolactacystin
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Cardiovascular Disease Neurological Disease Metabolic Disease Cancer
Pitavastatin lactone is a major metabolite of Pitavastatin (HY-B0144A) in humans. Pitavastatin is a potent competitive inhibitor of HMG-CoA reductase .
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Atorvastatin lactone is a metabolite of Atorvastatin acid, an HMG-CoA reductase inhibitor. Atorvastatin lactone exhibits myotoxicity .
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Rosuvastatin lactone is a metabolite of Rosuvastatin (HY-17504A) (HMG-CoA inhibitor) .
Cat. No.: HY-W008270
CAS No.: 497-23-4
Synonyms: γ-Crotonolactone
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2-Hydroxy atorvastatin calcium salt is an orally active OATP1B1 substrate and inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase (3-hydroxy-3-methylglutaryl-coenzyme A reductase). 2-Hydroxy atorvastatin calcium salt enters cells via OATP1B1-mediated cellular uptake and inhibits de novo hepatic cholesterol synthesis. As an active metabolite of Atorvastatin (HY-B0589), 2-Hydroxy atorvastatin calcium salt contributes to the inhibitory activity against plasma HMG-CoA reductase. 2-Hydroxy atorvastatin calcium salt can be biotransformed into an inactive lactone form, which can be hydrolyzed back to its active acid form chemically or enzymatically. 2-Hydroxy atorvastatin (calcium salt) can be used in the research of hypercholesterolemia .
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Pravastatin lactone is a potent HMG-CoA inhibitor. Pravastatin Lactone is a metabolite of pravastatin. Pravastatin lactone reduces blood cholesterol levels by inhibiting cholesterol synthesis .
Cat. No.: HY-W017445
CAS No.: 2688-48-4
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Cat. No.: HY-136410
CAS No.: 146764-24-1
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4-hydroxy Nonenal Mercapturic Acid is a major urinary metabolite of 4-hydroxy-2-nonenal (4-HNE). 4-hydroxy Nonenal Mercapturic Acid metabolites include reduced alcohols, aldehydes, and carboxylic acids, which further form gamma-lactols and gamma-lactones, resulting in 4-5 final urinary metabolites in vivo. 4-hydroxy Nonenal Mercapturic Acid can be used as a biomarker to assess oxidative stress .
Cat. No.: HY-133879
CAS No.: 81203-50-1
Synonyms: 1α,25-Dihydroxyvitamin D3-26,23-lactone
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Calcitriol lactone (1α,25-Dihydroxyvitamin D3-26,23-lactone) is a metabolite of vitamin D3. Calcitriol lactone is the active form of vitamin D and affects bone health, cell differentiation, immune function .
Cat. No.: HY-116246
CAS No.: 127708-42-3
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5(S)-HETE lactone is an arachidonic acid (AA) metabolite .
Cat. No.: HY-176301
Synonyms: Tetranor-prostaglandin D metabolite lactone
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Tetranor-PGDM lactone (Tetranor-prostaglandin D metabolite lactone) is a urinary metabolite of PGD2 (HY-101988). Prostaglandin D2 (PGD2) is one of the most potent endogenous sleep promoting substances. PGD2 plays a protective role by suppressing inflammation .
Cat. No.: HY-101873S
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3-Desacetyl Cefotaxime lactone is the active metabolite of Cefotaxime. Cefotaxime sodium salt is a third-generation cephalosporin antibiotic.
Cat. No.: HY-41982R
CAS No.: 32449-92-6
Synonyms: D-Glucurono-6,3-lactone (Standard); D-Glucurono-γ-lactone (Standard); D-Glucuronolactone (Standard); Dicurone (Standard); Glucoxy (Standard); Glucurolactone (Standard); Glucurone (Standard)
Cat. No.: HY-101873R
CAS No.: 125995-03-1
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Atorvastatin lactone (Standard) is the analytical standard of Atorvastatin lactone (HY-101873). This product is intended for research and analytical applications. Atorvastatin lactone is a metabolite of Atorvastatin acid, an HMG-CoA reductase inhibitor. Atorvastatin lactone exhibits myotoxicity .
Cat. No.: HY-136346S
CAS No.: 265989-50-2
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