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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
37 Results for "
macrophage migration inhibitory factor
" in MedChemExpress (MCE) Product Catalog:
Products (37)
37 Results for "macrophage migration inhibitory factor" in MCE Product Catalog:
25
Research Areas:
ISO-1 is a macrophage migration inhibitory factor (MIF) antagonist with an IC50 of 7 μM.
11
11 Cited Publications
Synonyms: 4-Iodo-6-phenylpyrimidine
Research Areas:
4-IPP (4-Iodo-6-phenylpyrimidine) is a specific suicide substrate and irreversible inhibitor of macrophage migration inhibitory factor (MIF) .
10
10 Cited Publications
Cat. No.: HY-P7387
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MIF; L-Dopachrome Isomerase; Prev. GLIF; Glycosylation-Inhibiting factor; Phenylpyruvate Tautomerase; MMIF; GIF; Epididymis Secretory Sperm Binding Protein; L-Dopachrome Tautomerase; macrophage migration inhibitory factor; macrophage migration inhibitory
Species:
Human
Source:
E. coli
5
Research Areas:
Iguratimod is an antirheumatic agent, acts as an inhibitor of COX-2, with an IC50 of 20 μM (7.7 μg/mL), but shows no effect on COX-1. Iguratimod also inhibits macrophage migration inhibitory factor (MIF) with an IC50 of 6.81 μM.
3
3 Cited Publications
Research Areas:
(±)-CPSI-1306 is an orally available antagonist of macrophage migration inhibitory factor (MIF).
3
3 Cited Publications
Cat. No.: HY-P7388
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MIF; L-Dopachrome Isomerase; Prev. GLIF; Glycosylation-Inhibiting factor; Phenylpyruvate Tautomerase; MMIF; GIF; Epididymis Secretory Sperm Binding Protein; L-Dopachrome Tautomerase; macrophage migration inhibitory factor; macrophage migration inhibitory
Species:
Mouse
Source:
E. coli
2
2 Cited Publications
Research Areas:
BTZO-1, a chemical probe, binds to Macrophage migration inhibitory factor (MIF) with a Kd value of 68.6 nM, and its binding requires the N-terminal Pro1. BTZO-1 can activate antioxidant response element (ARE)-mediated gene expression and suppress oxidative stress-induced cardiomyocyte apoptosis in vitro .
1
1 Cited Publications
Research Areas:
MIF098 is a macrophage migration inhibitory factor (MIF) antagonist. MIF098 inhibits proliferation, migration and fibrosis of pulmonary smooth muscle cells. MIF098 can be used for immunoinflammation-related disease research .
1
Cat. No.: HY-W019710
CAS No.: 1396841-57-8
Target:
Research Areas:
(E,E)-RGFP966 is a selective and CNS permeable HDAC3 inhibitor that can be used for the research of Huntington’s disease .
Research Areas:
MD13 is a MIF PROTAC degrader with a DC50 of approximately 100 nM. MD13 induces ubiquitination and degradation of MIF by recruiting the Cereblon Cullin RING E3 ubiquitin ligase complex. MD13 inactivates the MAPK pathway and induces G2/M phase cell cycle arrest. MD13 exhibits antiproliferative effects in 3D tumor spheroid models. MD13 can be used in lung cancer-related research .
Cat. No.: HY-D0039
CAS No.: 19088-73-4
Target:
Research Areas:
3-Cyanoumbelliferone is a coumarin derivative, acting as molecular probe and fluorescent dye. 3-Cyanoumbelliferone is also a macrophage migration inhibitory factor (MIF) tautomerase inhibitor with a Ki of 2.9 μM .
Cat. No.: HY-144190
CAS No.: 851095-20-0
Research Areas:
MIF-IN-1 (compound 14) is a potent macrophage migration inhibitory factor (MIF) inhibitor (pIC50=6.87) .
Cat. No.: HY-144196
CAS No.: 2489514-05-6
Research Areas:
MIF-IN-4 hydrochloride is potent macrophage migration inhibitory factor (MIF) inhibitor (pIC50=5.01-6). MIF is a cytokine originally found to play a role in inhibiting macrophage migration .
Cat. No.: HY-16692R
CAS No.: 478336-92-4
Synonyms: MIF Antagonist (Standard)
Research Areas:
ISO-1 (Standard) is the analytical standard of ISO-1. This product is intended for research and analytical applications. ISO-1 is a macrophage migration inhibitory factor (MIF) antagonist with an IC50 of 7 μM.
Research Areas:
R110 is a potent, competitive inhibitor of macrophage migration inhibitory factor 2 (MIF2) tautomerase with an IC50 of 15 μM. R110 has the potential for the research of cancer diseases .
Cat. No.: HY-146318
CAS No.: 2582755-31-3
Research Areas:
MIF-IN-5 (compound 1d) is a potent and reversible macrophage migration inhibitory factor (MIF) competitive inhibitor with an IC50 of 4.8 μM and a Ki value of 3.3 μM, respectively .
Cat. No.: HY-121356S
CAS No.: 1189661-02-6
Cat. No.: HY-121356S1
CAS No.: 1190019-51-2
Cat. No.: HY-146319
CAS No.: 2582758-61-8
Research Areas:
MIF-IN-6 (compound 2d) is a potent macrophage migration inhibitory factor (MIF) inhibitor with an IC50 of 1.4 μM and a Ki value of 0.96 μM, respectively. MIF-IN-6 attenuates MIF-induced ERK phosphorylation and inhibits proliferation of A549 cells .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
