1 Result for "

mossy

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "mossy" in MCE Product Catalog:

Cat. No.: HY-121299
CAS No.: 48144-44-1
Synonyms: mCPBG
Target:  

5-HT Receptor

Research Areas:  

Neurological Disease

m-Chlorophenylbiguanide (mCPBG) is a potent high-affinity agonist of the 5-HT3 receptor, exhibiting an inhibitory effect on long-term potentiation (LTP) in the mossy fiber-CA3 system. mCPBG attenuates the magnitude of LTP at concentrations of 0.3-1 microM, demonstrating its role in modulating synaptic plasticity. Additionally, the impact of mCPBG on LTP is reversible by the GABAA receptor antagonist bicuculline, indicating a connection between its action and GABAergic neurotransmission.
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