8 Results for "

mouse LOXL2

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "mouse LOXL2" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-107422
CAS No.: 2007885-39-2
Purity:  99.52%
Synonyms: PAT-1251; GB2064
Target:  

Monoamine Oxidase

Research Areas:  

Inflammation/Immunology

PAT-1251 is a potent, selective and oral lysyl oxidase-like 2 (LOXL2) inhibitor, with IC50s of 0.71 and 1.17 μM for hLOXL2 and hLOXL3, respectively, and also potently inhibits mouse, rat, and dog LOXL2 (IC50s, 0.10, 0.12, and 0.16 μM, respectively); PAT-1251 is used in the research of fibrotic diseases .
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Cat. No.: HY-127009
CAS No.: 68538-85-2
Synonyms: Levofolinic acid; Levofolene
Levoleucovorin (Levofolinic acid; Levofolene) is the pharmacologically and orally active levoisomer of Folinic acid (HY-17556), a synthetic folate analogue. Levoleucovorin can inhibit LOXL2 with an IC50 of 68.81 μM. Levoleucovorin can inhibit cancer cells proliferation, migration and induce apoptosis. Levoleucovorin can be used as a rescue agent for high-dose Methotrexate (HY-14519). Levoleucovorin can reduce the frequency of embryonic malformations. Levoleucovorin can be used for the research of can and endocrinology, such as breast cancer and osteosarcoma .
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Cat. No.: HY-P99047
CAS No.: 1318075-13-6
Synonyms: AB 0024; GS 6624
Simtuzumab (AB 0024; GS 6624) is a monoclonal antibody directed against Lysyl oxidase like-2 (LOXL2). Simtuzumab non-competitively blocks collagen cross-linking, reduces LOXL2 protein expression and attenuates extracellular matrix changes. Simtuzumab reduces myocardial fibrosis and prevents cardiac dysfunction. Simtuzumab lowers Myh7 and Nppa gene expression, reduces contraction heterogeneity, and cuts COL1A1 deposition. Simtuzumab can be used for the research of LMNA mutation-induced dilated cardiomyopathy, idiopathic pulmonary fibrosis, and primary sclerosing cholangitis .
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Cat. No.: HY-RS16627
Research Areas:  

Others

Loxl2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Loxl2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-107422A
CAS No.: 2098884-53-6
Synonyms: PAT-1251 hydrochloride; GB2064 hydrochloride
Target:  

Monoamine Oxidase

Research Areas:  

Inflammation/Immunology

PAT-1251 Hydrochloride is a potent, selective and oral lysyl oxidase-like 2 (LOXL2) inhibitor, with IC50s of 0.71 and 1.17 μM for hLOXL2 and hLOXL3, respectively, and also potently inhibits mouse, rat, and dog LOXL2 (IC50s, 0.10, 0.12, and 0.16 μM, respectively). PAT-1251 Hydrochloride is used in the research of fibrotic diseases.
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Cat. No.: HY-P74769
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Lysyl oxidase homolog 2; Lysyl oxidase-related protein WS9-14; LOXL2
Species:  
Source:  
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Cat. No.: HY-P74769Y
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Lysyl oxidase homolog 2; Lysyl oxidase-related protein WS9-14; LOXL2
Species:  
Source:  
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Cat. No.: HY-107422R
CAS No.: 2007885-39-2
Synonyms: PAT-1251 (Standard); GB2064 (Standard)
Lenumlostat (Standard) is the analytical standard of Lenumlostat (HY-107422). This product is intended for research and analytical applications. PAT-1251 is a potent, selective and oral lysyl oxidase-like 2 (LOXL2) inhibitor, with IC50s of 0.71 and 1.17 μM for hLOXL2 and hLOXL3, respectively, and also potently inhibits mouse, rat, and dog LOXL2 (IC50s, 0.10, 0.12, and 0.16 μM, respectively); PAT-1251 is used in the research of fibrotic diseases .
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