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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
mouse Leydig cells
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "mouse Leydig cells" in MCE Product Catalog:
Cat. No.: HY-W142432
CAS No.: 2058-94-8
Research Areas:
Perfluoroundecanoic acid is a perfluoroalkyl substance (PFAS). Perfluoroundecanoic acid is an orally active oxidative stress inducer. Perfluoroundecanoic acid promotes macrophage M2 polarization, activates Wnt/β-catenin signaling and enhances β-catenin nuclear accumulation. Perfluoroundecanoic acid -induced M2 phenotype macrophage accelerates tumor progression in vitro and in vivo. Perfluoroundecanoic acid induces DNA damage, reproductive and pathophysiological dysfunctions via oxidative stress in male Swiss mice. Perfluoroundecanoic acid inhibits Leydig cell development in pubertal male rats via inducing oxidative stress and autophagy. Perfluoroundecanoic acid accelerates insulitis development in a mouse model of type 1 diabetes. Perfluoroundecanoic acid can be used for the study of ovarian cancer, type 1 diabetes and inflammation .
Cat. No.: HY-134937
CAS No.: 950385-77-0
Target:
Research Areas:
BC8-15 is a PDE inhibitor with IC50 values of 0.28, 0.22, and 6.46 µM for inhibiting PDE8A, PDE4A, and PDE7A, respectively. BC8-15 can enhance steroidogenesis in mouse Leydig cells .
Cat. No.: HY-117671
CAS No.: 121242-02-2
Target:
Research Areas:
KS IV is a cyclolignan derivative and antigonadotropic agent. KS IV exhibits activity against pregnant mare serum gonadotropin (PMSG) but shows no activity against luteinizing hormone (LH). KS IV abolishes the stimulatory effect of PMSG on testosterone release from isolated mouse Leydig cells. KS IV can be used in studies on gonadotropin-regulated endocrine functions .
Cat. No.: HY-W142432S
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
