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Pathways Recommended:	Vitamin D Related/Nuclear Receptor

Results for "

nuclear factor erythroid 2-related factor 2

" in MedChemExpress (MCE) Product Catalog:

By Targets:	AMPK (1) Apoptosis (1) Cholinesterase (ChE) (1) ERK (1) Ferroptosis (2) Interleukin Related (1) Keap1-Nrf2 (7) Phosphoglycerate Kinase (PGK) (1) Reactive Oxygen Species (ROS) (1) Reference Standards (1)
By Research Areas:	Cancer (4) Inflammation/Immunology (1) Metabolic Disease (1) Neurological Disease (1)

7

Inhibitors & Agonists

1

Peptides

3

Recombinant Proteins

8

Antibodies

Targets Recommended: Orphan Nuclear Receptor NF-κB Nuclear Factor of activated T Cells (NFAT) Nuclear Hormone Receptor 4A/NR4A

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

ML385 Maximum Cited Publications 576 Publications Verification	Keap1-Nrf2 Ferroptosis	Cancer
ML385 is a specific nuclear factor erythroid 2-related factor 2 (NRF2) inhibitor with an IC₅₀ of 1.9 μM.

Nrf2-IN-1 5+ Cited Publications	Keap1-Nrf2	Cancer
Nrf2-IN-1 is an inhibitor of nuclear factor-erythroid 2-related factor 2 (Nrf2). Nrf2-IN-1 is developed for the research of acute myeloid leukemia (AML) .

ACA-28 1 Publications Verification	ERK Apoptosis Reactive Oxygen Species (ROS) Keap1-Nrf2	Cancer
ACA-28 is a potent ERK MAPK signaling modulator. ACA-28 selectively inhibits cancer cell growth and induces apoptosis. ACA-28 can activate nuclear factor erythroid 2-related factor 2 (Nrf2) signaling via inducing ROS production. ACA-28 can be used for the research of cancer, such as melanoma .

AChE/Nrf2 modulator 1	Cholinesterase (ChE) Keap1-Nrf2	Neurological Disease
AChE/Nrf2 modulator 1 is an orally active acetylcholinesterase (AChE)/nuclear factor erythroid 2-related factor 2 (Nrf2) modulator. AChE/Nrf2 modulator 1 has Nrf2 inductive activity and AChE inhibitory activity for eeAChE and hAChE with IC₅₀ values of 0.07 μM and 0.38 μM, respectively. AChE/Nrf2 modulator 1 can be used for the research of Alzheimer's disease .

DC-PGKI	Phosphoglycerate Kinase (PGK) Keap1-Nrf2 Interleukin Related	Inflammation/Immunology
DC-PGKI is an orally active ATP-competitive PGK1 inhibitor(IC₅₀ = 0.16 Μm, K_d = 99.08 nM). DC-PGKI stabilizes PGK1 in vitro and in vivo, and suppresses both glycolytic activity and the kinase function of PGK1. DC-PGKI-mediated inhibition of PGK1 leads to the accumulation of NRF2 (nuclear factor-erythroid factor 2-related factor 2, NFE2L2), which then translocates to the nucleus, binds to the proximal regions of IL-1β and IL-6 genes, and suppresses the LPS-induced expression of these genes. DC-PGKI can be used for the study of colitis .

YPLP	Keap1-Nrf2 AMPK	Metabolic Disease
YPLP is a yeast-derived peptide Tyr-Pro-Leu-Pro, which exhibits activity in anti fatigue mechanisms through the nuclear factor erythroid-2-related factor 2 (Nrf2)- and AMP-activated protein kinase (AMPK) pathway. YPLP is orally active .

ML385 (Standard)	Keap1-Nrf2 Reference Standards Ferroptosis	Cancer
ML385 (Standard) is the analytical standard of ML385 (HY-100523). This product is intended for research and analytical applications. ML385 is a specific nuclear factor erythroid 2-related factor 2 (NRF2) inhibitor with an IC50 of 1.9 μM.

Cat. No.	Product Name	Target	Research Area

YPLP	Keap1-Nrf2 AMPK	Metabolic Disease
YPLP is a yeast-derived peptide Tyr-Pro-Leu-Pro, which exhibits activity in anti fatigue mechanisms through the nuclear factor erythroid-2-related factor 2 (Nrf2)- and AMP-activated protein kinase (AMPK) pathway. YPLP is orally active .

Species:	Human (3)
Tag:	His (2) GST (1)
Source:	Sf9 insect cells (1) P. pastoris (1) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source	Image

	NFE2L2 Protein, Human (His) HEBP1; like 2; NF E2 related factor 2; NF-E2-related factor 2; nuclear factor erythroid 2-related factor 2	Human	E. coli
	The NFE2L2 protein is a key transcription factor that activates cytoprotective genes in response to oxidative stress by binding to the antioxidant response element (ARE). Normally, the BCR(KEAP1) complex degrades NFE2L2 in the cytoplasm. NFE2L2 Protein, Human (His) is the recombinant human-derived NFE2L2 protein, expressed by E. coli , with N-His labeled tag.

	NFE2L2 Protein, Human (P.pastoris, His) 5 Publications Verification HEBP1; like 2; NF E2 related factor 2; NF-E2-related factor 2; nuclear factor erythroid 2-related factor 2	Human	P. pastoris
	The NFE2L2 protein is a key transcription factor that activates cytoprotective genes in response to oxidative stress by binding to the antioxidant response element (ARE). Normally, the BCR(KEAP1) complex degrades NFE2L2 in the cytoplasm. NFE2L2 Protein, Human (P.pastoris, His) is the recombinant human-derived NFE2L2 protein, expressed by P. pastoris , with N-His labeled tag.

	NFE2L2 Protein, Human (sf9, GST) HEBP1; like 2; NF E2 related factor 2; NF-E2-related factor 2; nuclear factor erythroid 2-related factor 2	Human	Sf9 insect cells
	NFE2L2 is a key transcription factor that activates cytoprotective genes in response to oxidative stress by binding to the antioxidant response element (ARE). Normally, the BCR(KEAP1) complex degrades NFE2L2 in the cytoplasm. NFE2L2 Protein, Human (sf9, GST) is the recombinant human-derived NFE2L2 protein, expressed by Sf9 insect cells with N-GST labeled tag.

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Host:	Mouse (1) Rabbit (7)
Reactivity:	Human (8) Rat (3) Mouse (5)
Application:	IHC-P (7) ICC/IF (6) IF-Tissue (1) IP (4) IHC-F (1) WB (8) ChIP (2) FC (2) ELISA (2)
Isotype:	IgG (8)
Conjugation:	Non-conjugated (8)
Clonality:	Monoclonal (6) Recombinant (3)
Modification:	Phosphorylated (2) Unmodified (4)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

	Nrf2 Antibody (YA5510) nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; nuclear factor, erythroid derived 2, like 2;	WB, ICC/IF, ELISA	Human, Mouse, Rat
	Nrf2 Antibody (YA5510) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to Nrf2.

	Nrf2 Antibody (YA5784) nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; nuclear factor, erythroid derived 2, like 2;	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	Nrf2 Antibody (YA5784) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Nrf2.

	Nrf2 Antibody(YA895) 5 Publications Verification NFE2L2; NRF2; nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; nuclear factor; erythroid derived 2; like 2	WB, IHC-P, ICC/IF, IP, ChIP	Human, Mouse
	Nrf2 Antibody(YA895) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Nrf2.

	Phospho-Nrf2 (Ser40) Antibody (YA168) 2 Publications Verification NFE2L2; NRF2; nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; nuclear factor; erythroid derived 2; like 2	WB, ICC/IF, IHC-P, FC, IP	Human
	Phospho-Nrf2 (Ser40) Antibody (YA168) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-Nrf2 (Ser40).

	Phospho-Nrf2 (Ser40) Antibody (YA169) NFE2L2; NRF2; nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; nuclear factor; erythroid derived 2; like 2	WB, IHC-P	Human
	Phospho-Nrf2 (Ser40) Antibody (YA169) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-Nrf2 (Ser40).

	Nrf2 Antibody(YA895)(PBS only) NFE2L2; NRF2; nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; nuclear factor; erythroid derived 2; like 2	WB, IHC-P, ICC/IF, IP, ChIP	Human, Mouse
	Nrf2 Antibody(YA895) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Nrf2.

	Phospho-Nrf2 (Ser40) Antibody (YA169)(PBS only) NFE2L2; NRF2; nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; nuclear factor; erythroid derived 2; like 2	WB, IHC-P	Human
	Phospho-Nrf2 (Ser40) Antibody (YA169) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-Nrf2 (Ser40).

	Nrf2 Antibody (YA6356) NF2L2_HUMAN; nuclear factor erythroid 2-related factor 2; NFE2L2; NF-E2-related factor 2; NFE2-related factor 2; Nrf-2; Nrf 2; nuclear factor, erythroid derived 2, like 2; NFE2L2; NRF2; NFE2 like bZIP transcription factor 2; HEBP1; IMDDHH;	WB, IHC-P, IHC-F, IF-Tissue, FC, ICC/IF	Human, Mouse, Rat
	Nrf2 Antibody (YA6356) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Nrf2.

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