33 Results for "

oligopeptidase

" in MedChemExpress (MCE) Product Catalog:
Products (33)

33 Results for "oligopeptidase" in MCE Product Catalog:

Cat. No.: HY-E70448
CAS No.: 110639-28-6
Research Areas:  

Others

Oligopeptidase is a peptidase. Enzymes have high catalytic efficiency, high specificity, and mild operating conditions. It can be applied in industries such as pharmaceuticals, industrial production, food manufacturing, and aquaculture .
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2
2 Cited Publications
Cat. No.: HY-100684
CAS No.: 1448440-52-5
Purity:  99.51%
Research Areas:  

Cancer

UAMC-1110 is a highly potent and selective inhibitor of fibroblast activation protein (FAP) with an IC50 of 3.2 nM. UAMC-1110 also inhibits prolyl oligopeptidase (PREP) with an IC50 of 1.8 μM .
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1
1 Cited Publications
Cat. No.: HY-N2481
CAS No.: 36948-76-2
Synonyms: Oroxyloside; Oroxylin A-7-O-β-D-glucuronide
Oroxylin A-7-O-glucuronide (oroxyloside) is an orally active flavonoid glucuronide and metabolite of Oroxylin A (HY-N0560). Oroxylin A-7-O-glucuronide can be extracted from the dried root of Scutellaria baicalensis. Oroxylin A-7-O-glucuronide exhibits prolyl oligopeptidase inhibitory activity. Oroxylin A-7-O-glucuronide inhibits the JNK pathway, upregulates PPARγ, and inhibits NF-κB p65 nuclear translocation. Oroxylin A-7-O-glucuronide reduces cytokine (IL-1β, IL-6) production. Oroxylin A-7-O-glucuronide exhibits anti-angiogenic, anti-tumor (glioma, liver cancer), anti-inflammatory, and hepatoprotective activities .
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1
1 Cited Publications
Cat. No.: HY-100475
CAS No.: 796874-99-2
Purity:  99.93%
KYP-2047 is a potent and BBB-penetrating prolyl-oligopeptidase (POP) inhibitor, with an Ki value of 0.023 nM. KYP-2047 reduces glioblastoma proliferation through angiogenesis and apoptosis modulation .
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1
1 Cited Publications
Cat. No.: HY-145983
CAS No.: 80049-85-0
Purity:  99.16%
Research Areas:  

Cancer

Suc-Gly-Pro-AMC is a fluorescent substrate. Suc-Gly-Pro-AMC is a fibroblast activation protein (FAP) specific substrate. Suc-Gly-Pro-AMC reacts with recombinant porcine prolyl oligopeptidase. Suc-Gly-Pro-AMC can be used to study the activity of FAP, prolyl endopeptidase (PREP). Suc-Gly-Pro-AMC is used in glioma research .
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1
1 Cited Publications
Cat. No.: HY-W404002
CAS No.: 2505339-54-6
Research Areas:  

Metabolic Disease

BR102910 is a selective fibroblast activation protein (FAP) inhibitor with the IC50 of 2 nM. BR102910 also inhibits prolyl oligopeptidase (PREP) with the IC50 of 49.00 μM. BR102910 can be used for the researchof type 2
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Cat. No.: HY-W009004
CAS No.: 13184-14-0
Synonyms: Lys-Lys-Lys; H-Lys-Lys-Lys-OH
Research Areas:  

Others

Trilysine is a tripeptide and also a substrate for specific peptidases. Trilysine serves as a hydrolytic substrate for the tripeptide-specific aminopeptidase TP and the oligopeptidase OP .
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Cat. No.: HY-160289
CAS No.: 1426305-25-0
Research Areas:  

Others

ARI-3144 is a fluorogenic substrate for FAP with a FAP/PREP selectivity index of 15, and is processed by prolyl oligopeptidase (PREP) .
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Cat. No.: HY-139648
CAS No.: 2760543-16-4
Purity:  98.69%
Research Areas:  

Others

PREP inhibitor-1 (compound 27a) is a highly potent prolyl oligopeptidase (PREP) inhibitor (IC50 < 1 nM).
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Cat. No.: HY-P3792
CAS No.: 185698-23-1
Research Areas:  

Others

Mca-Pro-Leu-Gly-Pro-D-Lys(Dnp) is a FRET substrate of Thimet oligopeptidase. Mca-Pro-Leu-Gly-Pro-D-Lys(Dnp) can be used for the determination of Thimet oligopeptidase activity .
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Cat. No.: HY-134454
CAS No.: 108708-25-4
Purity:  98.03%
Research Areas:  

Infection

Z-Pro-Pro-CHO is a potent inhibitor of prolyl oligopeptidase (POP), with extremely high affinity for human prolyl oligopeptidase (HsPOP) (IC50=0.012 μM), and it also effectively inhibits the activity of Schistosoma mansoni prolyl oligopeptidase (SmPOP) (IC50=0.16 μM). Z-Pro-Pro-CHO does not block the phosphorylation of ERK or the production of TNF-α or IFN-γ in immune cells from presensitized mice, nor does it induce harmful phenotypes in cultured Schistosoma mansoni schistosomula. Z-Pro-Pro-CHO only partially inhibits epithelial cell wound healing at extremely high concentrations. Z-Pro-Pro-CHO finds wide application in studies related to schistosomiasis .
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Cat. No.: HY-143475
CAS No.: 2743432-81-5
Research Areas:  

Neurological Disease Cancer

POP-IN-2 (Compound 7k) is a potent, covalent prolyl oligopeptidase (POP) inhibitor with a Ki of 6 nM. POP-IN-2 can be used for studying neurodegenerative diseases and cancer .
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Cat. No.: HY-116828
CAS No.: 1432499-51-8
Research Areas:  

Cancer

ARI-3531 (compound 22) is a selective prolyl oligopeptidase (PREP) inhibitor (Ki=0.73 nM). ARI-3531 can be used to study tumor invasion and metastasis .
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Cat. No.: HY-P4926
CAS No.: 1802078-33-6
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Mca-SEVKMDAEFRK(Dnp)RR-NH2, containing the wild-type amyloid precursor protein (APP) beta-secretase cleavage site, is the substrate of thimet oligopeptidase (TOP). It is used for Alzheimer's disease research .
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Cat. No.: HY-N2481R
CAS No.: 36948-76-2
Synonyms: Oroxyloside (Standard); Oroxylin A-7-O-β-D-glucuronide (Standard)
Oroxylin A-7-O-glucuronide (Standard) is the analytical standard of Oroxylin A-7-O-glucuronide (HY-N2481). This product is intended for research and analytical applications. Oroxylin A-7-O-glucuronide (oroxyloside) is an orally active flavonoid glucuronide and metabolite of Oroxylin A (HY-N0560). Oroxylin A-7-O-glucuronide can be extracted from the dried root of Scutellaria baicalensis. Oroxylin A-7-O-glucuronide exhibits prolyl oligopeptidase inhibitory activity. Oroxylin A-7-O-glucuronide inhibits the JNK pathway, upregulates PPARγ, and inhibits NF-κB p65 nuclear translocation. Oroxylin A-7-O-glucuronide reduces cytokine (IL-1β, IL-6) production. Oroxylin A-7-O-glucuronide exhibits anti-angiogenic, anti-tumor (glioma, liver cancer), anti-inflammatory, and hepatoprotective activities .
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Cat. No.: HY-134454A
CAS No.: 88795-32-8
Synonyms: N-Benzyloxycarbonyl-L-prolyl-L-prolinal
Research Areas:  

Cardiovascular Disease

Z-Pro-prolinal (N-Benzyloxycarbonyl-L-prolyl-L-prolinal) is a specific, orally active prolyl endopeptidase (PREP) inhibitor with an IC50 of 0.4 nM for porcine PREP .
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Cat. No.: HY-W009004B
CAS No.: 3018057-84-3
Synonyms: Lys-Lys-Lys TFA; H-Lys-Lys-Lys-OH TFA
Target:  

Aminopeptidase

Research Areas:  

Others

Trilysine TFA is a tripeptide and also a substrate for specific peptidases. Trilysine TFA serves as a hydrolytic substrate for the tripeptide-specific aminopeptidase TP and the oligopeptidase OP .
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Cat. No.: HY-143474
CAS No.: 2554621-98-4
Research Areas:  

Neurological Disease Cancer

Y-29794 (Compound 2) is a potent, covalent prolyl oligopeptidase (POP) inhibitor with a Ki of 0.95 nM. Y-29794 can be used for studying neurodegenerative diseases and cancer .
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Cat. No.: HY-172207
Research Areas:  

Infection

POPTc80-IN-1 (Compound LC-45) is a competitive inhibitor for prolyl oligopeptidase of Trypanosoma cruzi POPTc80 with an IC50 of 0.23 μM and a Ki of 0.054 μM. POPTc80-IN-1 inhibits the invasion of T. cruzi into host cell with an IC50 of 46.71 μM .
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Cat. No.: HY-N16442
CAS No.: 428439-25-2
Pyrrocidine B (Compound 6), an alkaloid, is a microbial secondary metabolite. Pyrrocidine B can be isolated from the endophytic fungus Neonectria ramulariae Wollenw KS-246. Pyrrocidine B has significant cytotoxicity against leukemia cells (IC50 of 4.6  μM for HL60 cells) with a weak Prolyl oligopeptidase (POP) inhibitory activity .
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