1 Result for "

oxalamic ester

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "oxalamic ester" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-14530
CAS No.: 446022-33-9
Purity:  98.94%
Synonyms: AG 2037
Target:  

Antifolate

Research Areas:  

Cancer

Pelitrexol (AG 2037) is an inhibitor of glycinamide ribonucleotide formyltransferase (GARFT), a purine biosynthetic enzyme. Pelitrexol also inhibits mTORC1 by reducing GTP-bound Rheb level, a mTORC1 obligate activator. Pelitrexol shows robust tumor growth suppression in mice .
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