DAPM
DAPM is a Notch pathway inhibitor with anticancer activity and antiproliferative effects. DAPM effectively inhibits tubular adenoma development by inhibiting cell proliferation and inducing the expression of Krüppel-like factor 4 (KLF4) and p21 in human colon cancer cells.
For research use only. We do not sell to patients.
- CAS No.: 208255-51-0
- Formula: C20H20F2N2O4
- Molecular Weight:390.38
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | IC50 |
12 μM
Compound: DAPM
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Antiproliferative activity against human HCT116 cells after 72 hrs by SYBR green dye based fluorescence assay
Antiproliferative activity against human HCT116 cells after 72 hrs by SYBR green dye based fluorescence assay
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[PMID: 30201292] |
Chemical Information
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CAS No. 208255-51-0
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Molecular Weight 390.38
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Formula C20H20F2N2O4
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Sequence
N-[N-3,5-Difluorophenacetyl]-L-alanyl-S-phenylglycine methyl ester
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DAPM Related Classifications
HY-131923 Related Classifications
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