208255-51-0
208255-51-0
Chemical Structure
DAPM
- CAS No.: 208255-51-0
- Formula:C20H20F2N2O4
- Molecular Weight:390.38
IUPAC Name: methyl (S)-2-((S)-2-(2-(3,5-difluorophenyl)acetamido)propanamido)-2-phenylacetate
InChIKey: XAPDRNSTUYCSQC-SGTLLEGYSA-N
SMILES: FC1=CC(F)=CC(CC(N[C@@H](C)C(N[C@@H](C2=CC=CC=C2)C(OC)=O)=O)=O)=C1
Biological Activity: DAPM is a Notch pathway inhibitor with anticancer activity and antiproliferative effects. DAPM effectively inhibits tubular adenoma development by inhibiting cell proliferation and inducing the expression of Krüppel-like factor 4 (KLF4) and p21 in human colon cancer cells[1].
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DAPM | DAPM is a Notch pathway inhibitor with anticancer activity and antiproliferative effects. DAPM effectively inhibits tubular adenoma development by inhibiting cell proliferation and inducing the expression of Krüppel-like factor 4 (KLF4) and p21 in human colon cancer cells. | |||||||||||||||||||||
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References
Keywords
