195 Results for "

oxidant

" in MedChemExpress (MCE) Product Catalog:
Products (195)

195 Results for "oxidant" in MCE Product Catalog:

172
172 Publications Verification
Cat. No.: HY-16561
CAS No.: 501-36-0
Synonyms: trans-Resveratrol; SRT501
Resveratrol (trans-Resveratrol; SRT501) is a CNS-penetrant natural polyphenolic phytoalexin that possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. Resveratrol (SRT 501) has a wide spectrum of targets including mTOR, JAK, β-amyloid, Adenylyl cyclase, IKKβ, DNA polymerase. Resveratrol also is a specific SIRT1 activator . Resveratrol is a potent pregnane X receptor (PXR) inhibitor . Resveratrol is an Nrf2 activator, ameliorates aging-related progressive renal injury in mice model . Resveratrol increases production of NO in endothelial cells .
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30
30 Cited Publications
Cat. No.: HY-15097
CAS No.: 529-44-2
Purity:  98.42%
Synonyms: Cannabiscetin
Myricetin is a common plant-derived flavonoid with a wide range of activities including strong anti-oxidant, anticancer, antidiabetic and anti-inflammatory activities.
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19
19 Cited Publications
Cat. No.: HY-B0968
CAS No.: 13171-25-0
Target:  

Autophagy

Research Areas:  

Cardiovascular Disease

Trimetazidine dihydrochloride is a selective long chain 3-ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM, which can inhibit β-oxidation of free fatty acid (FFA). Trimetazidine dihydrochloride is an effective antianginal agent and a cytoprotective agent, has anti-oxidant, anti-inflammatory, antinociceptive and gastroprotective properties. Trimetazidine dihydrochloride triggers autophagy. Trimetazidine dihydrochloride is also a 3-hydroxyacyl-CoA dehydrogenase (HADHA) inhibitor .
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19
19 Cited Publications
Cat. No.: HY-B0968A
CAS No.: 5011-34-7
Target:  

Autophagy

Research Areas:  

Cardiovascular Disease

Trimetazidine is a selective long chain 3-ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM, which can inhibit β-oxidation of free fatty acid (FFA). Trimetazidine is an effective antianginal agent and a cytoprotective agent, has anti-oxidant, anti-inflammatory, antinociceptive and gastroprotective properties. Trimetazidine triggers autophagy. Trimetazidine is also a 3-hydroxyacyl-CoA dehydrogenase (HADHA) inhibitor .
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15
15 Cited Publications
Cat. No.: HY-N0056
CAS No.: 2450-53-5
Synonyms: 3,5-Dicaffeoylquinic acid; 3,5-CQA
Isochlorogenic acid A (3,5-Dicaffeoylquinic acid) is a natural phenolic acid with anti-mutagenicity, anti-HBV, anti-HIV, anti-oxidant, anti-bacterial, and anti-inflammatoryy activities .
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14
14 Cited Publications
Cat. No.: HY-N2302
CAS No.: 3351-86-8
Synonyms: all-trans-Fucoxanthin
Fucoxanthin (all-trans-Fucoxanthin) is a marine carotenoid and shows anti-obesity, anti-diabetic, anti-oxidant, anti-inflammatory and anticancer activities .
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14
14 Cited Publications
Cat. No.: HY-N0013
CAS No.: 3681-93-4
Vitexin is a c-glycosylated flavone, and is found in various medicinal plants species such as Trigonella foenum-graecum Linn. Vitexin has a wide range of pharmacological effects, including anti-oxidant, anti-cancer, anti-inflammatory, anti-hyperalgesic, and neuroprotective effects .
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14
14 Cited Publications
Cat. No.: HY-129457
CAS No.: 869298-31-7
Purity:  ≥98.0%
Target:  

Ferroptosis

Research Areas:  

Cancer

FINO2 is a potent ferroptosis inducer. FINO2 inhibits GPX4 activity. FINO2 is a stable oxidant that oxidizes ferrous iron and stable at varying pH levels. FINO2 causes widespread lipid peroxidation .
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13
13 Cited Publications
Cat. No.: HY-N0820
CAS No.: 2415-24-9
Synonyms: Catalpinoside
Catalpol (Catalpinoside), an iridoid glycoside found in Rehmannia glutinosa. Catalpol has neuroprotective, hypoglycemic, anti-inflammatory, anti-cancer, anti-spasmodic, anti-oxidant effects and anti-HBV effects .
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13
13 Cited Publications
Cat. No.: HY-N0784
CAS No.: 15291-77-7
Synonyms: BN-52021
Ginkgolide B (BN-52021), a terpene lactone, is a potent platelet activating factor antagonist. Ginkgolide B protects endothelial cells via the activation of PXR from injuries induced by xeno- and endobiotics. Ginkgolide B can pass through the brain-blood barrier. Ginkgolide B has anti-oxidant, anti-inflammatory, anti-tumor, and anti-apoptotic activity. Ginkgolide B has marked neuroprotective effects against ischemia-induced impairments .
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12
12 Cited Publications
Cat. No.: HY-109804
CAS No.: 1001015-18-4
Purity:  98.27%
Research Areas:  

Inflammation/Immunology

CORM-401 is an oxidant-sensitive CO-releasing molecule. CORM-401 induces NO increase in the regulation of endothelial calcium signalling. CORM-401 reduces TNF-α/CHX and H2O2-induced ROS production. CORM-401 uncouples mitochondrial respiration and inhibits glycolysis .
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11
11 Cited Publications
Cat. No.: HY-N0828
CAS No.: 537-42-8
Pterostilbene is a stilbenoid isolated from blueberries and Pterocarpus marsupium . Shows anti-oxidant, anti-inflammatory, anti-carcinogenic, anti-diabetic and anti-obesity properties . Pterostilbene blocks ROS production , also exhibits inhibitory activity against various free radicals such as DPPH, ABTS, hydroxyl, superoxide and hydrogen peroxide .
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9
9 Cited Publications
Cat. No.: HY-N1485
CAS No.: 78574-94-4
Synonyms: Astramembrangenin; Cyclosieversigenin
Cycloastragenol (Astramembrangenin), the active form of astragaloside IV, has anti-oxidant, anti-inflammatory, anti-aging, anti-apoptotic, and cardiovascular protective effects. Cycloastragenol is a potent telomerase activator and can lengthen telomeres. Cycloastragenol alleviates age-related bone loss and improves bone microstructure and biomechanical properties .
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9
9 Cited Publications
Cat. No.: HY-N0222
CAS No.: 572-30-5
Avicularin is an orally active flavonoid. Avicularin inhibits NF-κB (p65), COX-2 and PPAR-γ activities. Avicularin has anti-inflammatory, anti-infectious anti-allergic, anti-oxidant, hepatoprotective, and anti-tumor activities .
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8
8 Cited Publications
Cat. No.: HY-P2902
CAS No.: 9001-37-0
Research Areas:  

Cancer

Glucose oxidase is used in the food and beverage industry as a preservative and stabilizer and is commonly derived from the fungus Aspergillus niger. Glucose oxidase can react with intracellular glucose and oxygen (O2) to produce hydrogen peroxide (H2O2) and gluconic acid, which can cut off the nutrition source of cancer cells and consequently inhibit their proliferation .
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8
8 Cited Publications
Cat. No.: HY-12022
CAS No.: 3544-24-9
Purity:  99.99%
Synonyms: PARP-IN-1
Target:  

PARP

Research Areas:  

Cancer

3-Aminobenzamide (PARP-IN-1) is a potent inhibitor of PARP with IC50 of appr 50 nM in CHO cells, and acts as a mediator of oxidant-induced myocyte dysfunction during reperfusion.
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7
7 Cited Publications
Cat. No.: HY-D1713
CAS No.: 850013-49-9
CM-H2DCFDA is a derivative of H2DCFDA (HY-D0940). CM-H2DCFDA can be used to determine cellular oxidant levels (Ex/Em: 495/530 nm). CM-H2DCFDA is light-sensitive .
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7
7 Cited Publications
Cat. No.: HY-N3442
CAS No.: 5041-67-8
Juglanin, a occurring flavonoid that can be isolated from crude Polygonum aviculare, is a JNK acticator, with anti-inflammatory, anti-oxidant and anti-tumor activities. Juglanin can induce apoptosis and autophagy on human breast cancer cells .
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6
6 Cited Publications
Cat. No.: HY-N0773
CAS No.: 38953-85-4
Synonyms: Saponaretin; Homovitexin
Isovitexin is a flavonoid isolated from passion flower, Cannabis and, and the palm, possesses anti-inflammatory and anti-oxidant activities; Isovitexin acts like a JNK1/2 inhibitor and inhibits the activation of NF-κB.
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6
6 Cited Publications
Cat. No.: HY-N0790
CAS No.: 545-47-1
Synonyms: Clerodol; Monogynol B; Fagarasterol
Lupeol (Clerodol; Monogynol B; Fagarasterol) is an active pentacyclic triterpenoid, has anti-oxidant, anti-mutagenic, anti-tumor and anti-inflammatory activity. Lupeol is a potent androgen receptor (AR) inhibitor and can be used for cancer research, especially prostate cancer of androgen-dependent phenotype (ADPC) and castration resistant phenotype (CRPC) .
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