2. Apoptosis
  3. Ferroptosis
  4. FINO2

FINO2 is a potent ferroptosis inducer. FINO2 inhibits GPX4 activity. FINO2 is a stable oxidant that oxidizes ferrous iron and stable at varying pH levels. FINO2 causes widespread lipid peroxidation.

For research use only. We do not sell to patients.

FINO2 Chemical Structure

FINO2 Chemical Structure

CAS No. : 869298-31-7

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1 mg USD 65 In-stock
5 mg USD 160 In-stock
10 mg USD 260 In-stock
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Based on 1 publication(s) in Google Scholar

FINO2 Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE FINO2

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Description

FINO2 is a potent ferroptosis inducer. FINO2 inhibits GPX4 activity. FINO2 is a stable oxidant that oxidizes ferrous iron and stable at varying pH levels. FINO2 causes widespread lipid peroxidation[1].

In Vitro

FINO2 (10 µM; 24 h) induce ferroptosis and shows iron dependence of lipid peroxidation in HT-1080 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

FINO2 Related Antibodies
Molecular Weight

256.38

Formula

C15H28O3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OCCC1(C[C@](CC[C@H]2C(C)(C)C)(CC2)OO1)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (195.02 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.9005 mL 19.5023 mL 39.0046 mL
5 mM 0.7801 mL 3.9005 mL 7.8009 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥98.0%

COA (245 KB) HNMR (260 KB) MS (177 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.9005 mL 19.5023 mL 39.0046 mL 97.5115 mL
5 mM 0.7801 mL 3.9005 mL 7.8009 mL 19.5023 mL
10 mM 0.3900 mL 1.9502 mL 3.9005 mL 9.7512 mL
15 mM 0.2600 mL 1.3002 mL 2.6003 mL 6.5008 mL
20 mM 0.1950 mL 0.9751 mL 1.9502 mL 4.8756 mL
25 mM 0.1560 mL 0.7801 mL 1.5602 mL 3.9005 mL
30 mM 0.1300 mL 0.6501 mL 1.3002 mL 3.2504 mL
40 mM 0.0975 mL 0.4876 mL 0.9751 mL 2.4378 mL
50 mM 0.0780 mL 0.3900 mL 0.7801 mL 1.9502 mL
60 mM 0.0650 mL 0.3250 mL 0.6501 mL 1.6252 mL
80 mM 0.0488 mL 0.2438 mL 0.4876 mL 1.2189 mL
100 mM 0.0390 mL 0.1950 mL 0.3900 mL 0.9751 mL
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FINO2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FINO2869298-31-7FINO 2FINO-2FerroptosisHT-1080 cellsGPX4peroxidationoxidizes ironInhibitorinhibitorinhibit

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