545-47-1
Chemical Structure
Lupeol
Synonym(s): Clerodol; Monogynol B; Fagarasterol
- CAS No.: 545-47-1
- Formula:C30H50O
- Molecular Weight:426.72
IUPAC Name: (1R,3aR,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-3a,5a,5b,8,8,11a-hexamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysen-9-ol
InChIKey: MQYXUWHLBZFQQO-QGTGJCAVSA-N
SMILES: C[C@]1([C@@]2(CC[C@@]3([H])C4(C)C)C)[C@@](CC[C@]2([H])[C@]3(CC[C@@H]4O)C)([H])[C@]([C@@H]5C(C)=C)([H])[C@](C)(CC5)CC1
Biological Activity: Lupeol (Clerodol; Monogynol B; Fagarasterol) is an active pentacyclic triterpenoid, has anti-oxidant, anti-mutagenic, anti-tumor and anti-inflammatory activity. Lupeol is a potent androgen receptor (AR) inhibitor and can be used for cancer research, especially prostate cancer of androgen-dependent phenotype (ADPC) and castration resistant phenotype (CRPC)[1].
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Lupeol | 98.0% | Lupeol (Clerodol; Monogynol B; Fagarasterol) is an active pentacyclic triterpenoid, has anti-oxidant, anti-mutagenic, anti-tumor and anti-inflammatory activity. Lupeol is a potent androgen receptor (AR) inhibitor and can be used for cancer research, especially prostate cancer of androgen-dependent phenotype (ADPC) and castration resistant phenotype (CRPC). | ||||||||||||||||||||
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Lupeol (Standard) | 99.89% | Lupeol (Standard) is the analytical standard of Lupeol. This product is intended for research and analytical applications. Lupeol (Clerodol; Monogynol B; Fagarasterol) is an active pentacyclic?triterpenoid, has anti-oxidant, anti-mutagenic, anti-tumor and anti-inflammatory activity. Lupeol is a potent?androgen receptor (AR)?inhibitor and can be used for cancer research, especially prostate cancer of androgen-dependent phenotype (ADPC) and castration resistant phenotype (CRPC). | ||||||||||||||||||||
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28-Aminobetulin | 28-Aminobetulin is a pentacyclic triterpenoid and a derivative of the cholesterol biosynthesis inhibitor Betulin (HY-N0083). | |||||||||||||||||||||
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Betulin (GMP) | Betulin (GMP) (Trochol (GMP)) is Betulin (HY-N0083) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Betulin (Trochol), is a sterol regulatory element-binding protein (SREBP) inhibitor with an IC50 of 14.5 μM in K562 cell line. | |||||||||||||||||||||
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Betulinaldehyde | 98.01% | Betulinaldehyde (Betunal) Has anti-cancer and anti-staphylococcus aureus activity. Betulinaldehyde Suppressible Akt, MAPK sum STAT3 Signal path, increase self-transfer, Suppression A549 Cellular vitality, increase and transfer. Betulinaldehyde suppresses PLCγ1/Ca2+/MMP9 signal pathway, has a key effect on vascular plasticity, and is available for cardiovascular disease (CVD) research. | ||||||||||||||||||||
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3β-Hydroxy-hop-22(29)-ene | 3β-Hydroxy-hop-22(29)-ene (compound 3) is a potent antiparasitic agent. 3β-Hydroxy-hop-22(29)-ene shows moderate activity against Trypanosoma cruzi and Leishmania mexicana. | |||||||||||||||||||||
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Lup-20(29)-ene-2α,3α-diol | Lup-20(29)-ene-2α,3α-diol is a natural triterpene. | |||||||||||||||||||||
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30-Oxolupeol | 30-Oxolupeol is a Triterpenoids product that can be isolated from the leaves of Ilex cornuta.. | |||||||||||||||||||||
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(3β,4α)-Lup-20(29)-ene-3,23-diol | (3β,4α)-Lup-20(29)-ene-3,23-diol (compound 11) is a natural lupane-type triterpenes betulinic acid with anti-tumor activity. | |||||||||||||||||||||
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Lup-20(29)-ene-3α,23-diol | Lup-20(29)-ene-3α,23-diol is a natural triterpene. | |||||||||||||||||||||
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Lup-20(29)-ene-2alpha,3beta-diol | Lup-20(29)-ene-2alpha,3beta-diol (20(29)-Lupene-2α,3β-diol) is a phenol product that can be isolated from Chinese bog bilberry wines. | |||||||||||||||||||||
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Hennadiol | Hennadiol (Lup-20(29)-ene-3β,30-diol) is a product that can be isolated from . | |||||||||||||||||||||
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