9 Results for "

peptide transport systems

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "peptide transport systems" in MCE Product Catalog:

Cat. No.: HY-P4073
CAS No.: 1075214-55-9
Synonyms: GRN1005; Paclitaxel trevatide
Research Areas:  

Cancer

ANG1005 (Paclitaxel trevatide) is a brain-penetrating peptide-drug conjugate. ANG1005, a taxane derivative, consists of three paclitaxel (HY-B0015) molecules covalently linked to Angiopep-2, designed to cross the blood-brain and blood-cerebrospinal barriers and to penetrate malignant cells via low density lipoprotein receptor-related protein (LRP1) transport system .
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Cat. No.: HY-WAA0142
CAS No.: 2578-57-6
L-Prolylglycine is a proline-glycine dipeptide. L-Prolylglycine is absorbable through the jejunal and ileal mucosa. In streptozotocin (HY-13753)-induced diabetic mice, L-Prolylglycine reduces hepatic ALT activity and increases hepatic ALP activity. L-Prolylglycine prevents excessive elevation of blood glucose in diabetic mice. L-Prolylglycine is applicable to diabetes-related research .
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Cat. No.: HY-131286A
CAS No.: 441765-97-5
Synonyms: LY-544344 (hydrochloride)
Target:  

Drug Derivative mGluR

Research Areas:  

Neurological Disease

Talaglumetad hydrochloride (LY-544344 hydrochloride) is an orally active prodrug of Eglumegad (HY-18941) and a metabotropic glutamate receptor 2/3 (mGluR2/3) agonist. Talaglumetad hydrochloride undergoes transmembrane transport via the intestinal peptide transporter hPepT1, and is enzymatically hydrolyzed to produce L-alanine and the parent drug Eglumegad after entering the body. Talaglumetad hydrochloride can be used in research related to metabotropic glutamate receptor 2-associated neurological systems .
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Cat. No.: HY-P4668
CAS No.: 3989-97-7
Synonyms: Val-Leu; H-Val-Leu-OH
Target:  

Bacterial

Research Areas:  

Infection

Valylleucine (Val-Leu; H-Val-Leu-OH) is a branched-chain dipeptide that can enter cells independently via bacterial dipeptide transport systems, and is hydrolyzed by dipeptidases to release Val and Leu. Valylleucine, as a model peptide, has its α-amino pK determined to be 7.90 by combining FDNB reaction kinetics with potentiometric titration .
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Cat. No.: HY-P4668A
CAS No.: 27530-02-5
Synonyms: Val-Leu TFA; H-Val-Leu-OH TFA
Target:  

Bacterial

Research Areas:  

Infection

Valylleucine (Val-Leu; H-Val-Leu-OH) TFA is a branched-chain dipeptide that can enter cells independently via bacterial dipeptide transport systems, and is hydrolyzed by dipeptidases to release Val and Leu. Valylleucine TFA, as a model peptide, has its α-amino pK determined to be 7.90 by combining FDNB reaction kinetics with potentiometric titration .
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Cat. No.: HY-P11423
Target:  

Inhibitory Antibodies

Research Areas:  

Others

CSK peptide is a peptide that improves transport of macromolecules across the intestinal mucosal barrier targeting goblet cells. CSK peptide can be used for oral delivery system research .
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Cat. No.: HY-124218
CAS No.: 130024-92-9
Target:  

Antibiotic

Research Areas:  

Others

S 863390 is a compound with the ability to inhibit the intestinal uptake system, which can interact with the intestinal uptake system to inhibit the uptake of β-lactam antibiotics and small peptides while also being transported itself.
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Cat. No.: HY-118707
CAS No.: 14486-15-8
Synonyms: Met-met-met
Research Areas:  

Infection

Trimethionine (Met-met-met) is an orally active tripeptide substrate of peptide transport systems. Trimethionine interacts with the triple-leucine-triple-threonine transport system and the oligopeptide permease (Opp) system in Escherichia coli, competing for uptake and transport processes. Trimethionine antagonizes the toxicity of threonine tripeptide and ornithine tripeptide, and competes with peptide-supported growth and amino acid source utilization processes in Escherichia coli strains. Trimethionine is taken up by Candida albicans via a carrier-mediated, energy-dependent manner, and is subsequently hydrolyzed into free methionine intracellularly. Trimethionine can be used in studies related to Candida albicans infections .
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Cat. No.: HY-131286
CAS No.: 441765-98-6
Synonyms: LY-544344
Target:  

mGluR

Research Areas:  

Neurological Disease

Talaglumetad (LY-544344) is an orally active prodrug of Eglumegad (HY-18941) and a metabotropic glutamate receptor 2/3 (mGluR2/3) agonist. Talaglumetad undergoes transmembrane transport via the intestinal peptide transporter hPepT1, and is enzymatically hydrolyzed to produce L-alanine and the parent drug Eglumegad after entering the body. Talaglumetad can be used in research related to metabotropic glutamate receptor 2-associated neurological systems .
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