Trimethionine

Trimethionine competes with trileucine for utilization by the Opp⁺ and Opp^- strains of Escherichia coli K-12 TD-V, indicating that it can be recognized by the trileucine-threonine transport system^[1].
Trimethionine can be transported via the general oligopeptide transport system (Opp) in Escherichia coli W M-26-26, as it alleviates triornithine toxicity through competitive uptake inhibition^[1].
Trimethionine competes with tetra-lysine for utilization in Escherichia coli W M-26-26, confirming that it is a substrate of the general oligopeptide transport system (Opp)^[1].
Trimethionine is taken up by Candida albicans WD 18-4 via a saturable, energy-dependent carrier-mediated system; upon uptake, it is rapidly hydrolyzed to free methionine by intracellular peptidases immediately^[3].
The transport system for Trimethionine in Candida albicans WD 18-4 is highly specific, and it strongly recognizes tripeptides with hydrophobic side chains, an N-terminal acetyl group, or a D-type residue at the first position^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.