Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
125 Results for "
poisons
" in MedChemExpress (MCE) Product Catalog:
Products (125)
125 Results for "poisons" in MCE Product Catalog:
28
28 Publications Verification
Cat. No.: HY-W018746
CAS No.: 139-33-3
Synonyms: Ethylenediaminetetraacetic acid disodium
27
27 Cited Publications
Cat. No.: HY-W250119
CAS No.: 23411-34-9
Synonyms: EDTA disodium calcium salt hydrate; Ethylenediaminetetraacetic acid disodium calcium salt hydrate
4
Target:
Research Areas:
Fomepizole (4-Methylpyrazole) is a potent cytochrome P450 (CYP2E1) inhibitor. Fomepizole is a competitive inhibitor of the enzyme alcohol dehydrogenase. Fomepizole blocks further conversion of methanol and ethylene glycol to toxic metabolites. Fomepizole has the potential for an antidote for ethylene glycol or methanol poisoning .
4
4 Cited Publications
Cat. No.: HY-B0876A
CAS No.: 56010-88-9
Synonyms: 4-Methylpyrazole hydrochloride
Target:
Research Areas:
Fomepizole (4-Methylpyrazole) hydrochloride is a potent and orally active cytochrome P450 (CYP2E1) inhibitor. Fomepizole hydrochloride is a competitive inhibitor of the enzyme alcohol dehydrogenase. Fomepizole hydrochloride blocks further conversion of methanol and ethylene glycol to toxic metabolites. Fomepizole hydrochloride has the potential for an antidote for ethylene glycol or methanol poisoning .
3
Target:
3
Target:
Research Areas:
Pralidoxime chloride is a potent reactivator of acetylcholinesterase (AChE). Pralidoxime chloride reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime chloride is an antidote for organophosphate poisoning .
2
Target:
2
Target:
Research Areas:
Physostigmine salicylate (Eserine salicylate) is a reversible acetylcholinesterase (AChE) inhibitor. Physostigmine salicylate crosses the blood-brain barrier and stimulates central cholinergic neurotransmission. Physostigmine salicylate can reverse memory deficits in transgenic mice with Alzheimer's disease. Physostigmine salicylate is also an antidote for anticholinergic poisoning .
2
Category:
Alkaloids Neurological Disease Other Alkaloids Anisodus tanguticus (Maxinowicz) Pascher Plants Solanaceae Disease Research Fields
Target:
2
Target:
Research Areas:
Physostigmine hemisulfate (Eserine hemisulfate) is a reversible acetylcholinesterase (AChE) inhibitor. Physostigmine hemisulfate can crosses the blood-brain barrier and stimulates central cholinergic neurotransmission. Physostigmine hemisulfate can reverse memory deficits in transgenic mice with Alzheimer's disease. Physostigmine hemisulfate is also an antidote for anticholinergic poisoning .
2
Research Areas:
Temephos (Temefos) is an orally active, blood-brain barrier-permeable organophosphate insecticide and AChE inhibitor. By irreversibly inhibiting AChE to induce cholinergic overactivation, Temephos effectively blocks larval development of Aedes aegypti (yellow fever mosquito) and Aedes albopictus (Asian tiger mosquito), and is commonly used in studies related to Dengue Virus, Zika Virus and other relevant pathogens. Temephos exhibits genotoxicity and neurodevelopmental toxicity, and may also cause liver injury, reproductive system abnormalities and cholinergic poisoning symptoms in mammals. Temephos tends to accumulate in adipose tissues and aquatic organisms, and is excreted via feces after metabolism through oxidation and hydrolysis. Note that CYP-mediated metabolic detoxification may reduce the actual larvicidal efficacy of Temephos against some mosquito species. Temephos can be used in research related to dengue fever, Zika virus disease, chikungunya and dracunculiasis .
1
1 Cited Publications
Synonyms: 2,3-Dimercapto-1-propanol; Dithioglycerol
Dimercaprol (2,3-Dimercapto-1-propanol) is an anti-heavy metal-poisoning agent, which exhibits anti-HIV activity. Dimercaprol can be used for the study for arsenic, mercury, gold, lead, antimony, and other toxic metal poisoning .
1
Target:
1
Target:
1
1
Target:
1
1 Cited Publications
Cat. No.: HY-W011108
CAS No.: 114-90-9
Target:
Research Areas:
Obidoxime dichloride is a non-full spectrum oxime agent and can be used as an antidote for organophosphate nerve agent poisoning. Obidoxime dichloride reactivates sarin-inhibited acetylcholinesterase (AChE) and reduces acute toxicity of sarin-evaluated .
1
1 Cited Publications
Target:
Research Areas:
Coralyne chloride is a protoberberine alkaloid with potent anti-cancer activities. Coralyne chloride acts as a potent topoisomerase I poison and induces Top I mediated DNA cleavage . Coralyne chloride can be used for preparing?coralyne derivatives?as DNA binding fluorescent probes .
1
Category:
Monophenols Ketones, Aldehydes, Acids Other Diseases Phenols Endogenous metabolite Disease Research Fields
Target:
1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
