1. Neuronal Signaling
  2. AChE
  3. Obidoxime dichloride

Obidoxime dichloride 

Cat. No.: HY-W011108
Handling Instructions

Obidoxime dichloride is a non-full spectrum oxime agent and can be used as an antidote for organophosphate nerve agent poisoning. Obidoxime dichloride reactivates sarin-inhibited acetylcholinesterase (AChE) and reduces acute toxicity of sarin-evaluated.

For research use only. We do not sell to patients.

Obidoxime dichloride Chemical Structure

Obidoxime dichloride Chemical Structure

CAS No. : 114-90-9

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Description

Obidoxime dichloride is a non-full spectrum oxime agent and can be used as an antidote for organophosphate nerve agent poisoning. Obidoxime dichloride reactivates sarin-inhibited acetylcholinesterase (AChE) and reduces acute toxicity of sarin-evaluated[1].

In Vivo

Obidoxime dichloride (intramuscular injection; 10 mg/kg; after 60 mins) exhibits a LD50 of 57.7 mg/kg after administration of sarin, and it reduces reduces acute toxicity of sarin was evaluated[1].

Animal Model: NMRI male mice
Dosage: 10 mg/kg
Administration: Intramuscular injection
Result: Was effective in reactivating sarin-inhibited acetylcholinesterase (AChE).
Molecular Weight

359.21

Formula

C₁₄H₁₆Cl₂N₄O₃

CAS No.

114-90-9

SMILES

O/N=C/C1=CC=[N+](C=C1)COC[N+]2=CC=C(C=C2)/C=N/O.[Cl-].[Cl-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Obidoxime dichlorideAChEAcetylcholinesteraseacutetoxicityacetylcholinesterasesarinInhibitorinhibitorinhibit

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Obidoxime dichloride
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