Obidoxime dichloride
Based on 1 publication(s) in Google Scholar
Obidoxime dichloride is a non-full spectrum oxime agent and can be used as an antidote for organophosphate nerve agent poisoning. Obidoxime dichloride reactivates sarin-inhibited acetylcholinesterase (AChE) and reduces acute toxicity of sarin-evaluated.
For research use only. We do not sell to patients.
- Purity: 99.28%
- CAS No.: 114-90-9
- Formula: C14H16Cl2N4O3
- Molecular Weight:359.21
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Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Obidoxime dichloride
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Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:NMRI male mice
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Dosage:10 mg/kg
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Administration:Intramuscular injection
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Result:Was effective in reactivating sarin-inhibited acetylcholinesterase (AChE).
Chemical Information
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CAS No. 114-90-9
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Appearance Solid
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Molecular Weight 359.21
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Formula C14H16Cl2N4O3
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Color Off-white to light yellow
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SMILES
O/N=C/C1=CC=[N+](C=C1)COC[N+]2=CC=C(C=C2)/C=N/O.[Cl-].[Cl-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Publications (1)
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Journal Impact Factor
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Most Recent
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Mater Today Bio
Engineered acetylcholinesterase-loaded dissolvable microneedles mitigate dermal toxicity by targeting trichlorfon binding and metabolic pathway modulation. [Abstract]2026 May 14:38:103243. PMID: 42182869
Solvent & Solubility
H2O : 100 mg/mL (278.39 mM; Need ultrasonic)
DMSO : 1 mg/mL (2.78 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O | 1 mM | 2.7839 mL | 13.9194 mL | 27.8389 mL | 69.5972 mL |
| H2O | 5 mM | 0.5568 mL | 2.7839 mL | 5.5678 mL | 13.9194 mL |
| 10 mM | 0.2784 mL | 1.3919 mL | 2.7839 mL | 6.9597 mL | |
| 15 mM | 0.1856 mL | 0.9280 mL | 1.8559 mL | 4.6398 mL | |
| 20 mM | 0.1392 mL | 0.6960 mL | 1.3919 mL | 3.4799 mL | |
| 25 mM | 0.1114 mL | 0.5568 mL | 1.1136 mL | 2.7839 mL | |
| 30 mM | 0.0928 mL | 0.4640 mL | 0.9280 mL | 2.3199 mL | |
| 40 mM | 0.0696 mL | 0.3480 mL | 0.6960 mL | 1.7399 mL | |
| 50 mM | 0.0557 mL | 0.2784 mL | 0.5568 mL | 1.3919 mL | |
| 60 mM | 0.0464 mL | 0.2320 mL | 0.4640 mL | 1.1600 mL | |
| 80 mM | 0.0348 mL | 0.1740 mL | 0.3480 mL | 0.8700 mL | |
| 100 mM | 0.0278 mL | 0.1392 mL | 0.2784 mL | 0.6960 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Obidoxime dichloride Related Classifications
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