304-55-2
304-55-2
Chemical Structure
Succimer
Synonym(s): Dimercaptosuccinic acid; DMSA
- CAS No.: 304-55-2
- Formula:C4H6O4S2
- Molecular Weight:182.22
IUPAC Name: (2R,3S)-2,3-dimercaptosuccinic acid
InChIKey: ACTRVOBWPAIOHC-XIXRPRMCSA-N
SMILES: O=C(O)[C@@H](S)[C@@H](S)C(O)=O
Biological Activity: Succimer is a widely used chelating agent for the treatment of Pb poisoning.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Succimer | 98.0% | Succimer is a widely used chelating agent for the treatment of Pb poisoning. | ||||||||||||||||||||
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Succimer (Standard) | ≥98% | Succimer (Standard) is the analytical standard of Succimer. This product is intended for research and analytical applications. Succimer is a widely used chelating agent for the treatment of Pb poisoning. | ||||||||||||||||||||
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Aurothiomalate sodium | 98.0% | Aurothiomalate sodium acts as an inhibitor of PKCI and TrxR1. Aurothiomalate sodium disrupts the PKCI-Par6-Rac1 signaling pathway, and also inhibits TrxR1 activity, TNFα-induced NF-κB activation, and the expression of pro-inflammatory genes. Aurothiomalate sodium blocks Kras-mediated BASC expansion and lung tumor growth, inhibits anchorage-independent growth and tumorigenicity of lung cancer cells, and suppresses neutrophil chemotaxis, phagocytosis, and leukocyte extravasation. Aurothiomalate sodium can be used in research related to rheumatoid arthritis and non-small cell lung cancer. | ||||||||||||||||||||
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3-Methylglutaric acid | 98.0% | 3-Methylglutaric acid is a non-selective inhibitor of mitochondrial function and Na+, K+-ATPase, with an inhibition rate of 30% on rat cortical synaptosomal Na+, K+-ATPase. 3-Methylglutaric acid can induce reactive oxygen species (ROS) generation, thereby causing oxidative damage and inhibiting mitochondrial redox potential and ion pump function of cell membranes. 3-Methylglutaric acid can be used to study the neuropathological mechanisms of metabolic diseases and the role of oxidative stress-mediated neuronal damage in neurodegeneration. | ||||||||||||||||||||
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3-Hydroxyglutaric acid (Standard) | ≥98% | 3-Hydroxyglutaric acid (Standard) is the analytical standard of 3-Hydroxyglutaric acid. This product is intended for research and analytical applications. 3-Hydroxyglutaric acid is a glutaric acid derivative. | ||||||||||||||||||||
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Pregabalin diacid | 98.47% | Pregabalin diacid is an impurity of Pregabalin, a lipophilic GABA (γ-aminobutyric acid) analog with anxiolytic and anticonvulsant activity. Pregabalin may act on the α(2)β subunit of voltage-dependent calcium channels, which are widely distributed in the peripheral and central nervous systems. Pregabalin can effectively induce hypoalgesia and improve behavioral disorders. | ||||||||||||||||||||
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MiADMSA | MiADMSA (Monoisoamyl meso-2,3-dimercaptosuccinic acid) is an orally active thiol chelator that can effectively remove heavy metals such as arsenic and lead from the body of animals. Arsenic binds with two vicinal sulfhydryl groups available in MiADMSA leading to marked reduction in body arsenic burden and also marked reduction in various oxidative stress parameters and antioxidant enzymes like-ROS, nitrite, TBARS, GSH, SOD and catalase. MiADMSA attenuates urinary bladder carcinogenesis, protects against oxidative stress, ameliorates copper-induced histopathology, reverses neurotoxicity, and is safe in animals. MiADMSA can be used in studies of bladder cancer, arsenic, and lead-induced developmental neurotoxicity. | |||||||||||||||||||||
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Ethylmalonic acid | 98.0% | Ethylmalonic acid is a short-chain organic dicarboxylic acid. Ethylmalonic acid synergistically induces mitochondrial permeability transition (MP) with Ca2+, inhibits Mi-CK, and disrupts mitochondrial energy metabolism. Ethylmalonic acid can be used in the research of SCADD, EE and other genetic metabolic diseases characterized by EMA accumulation. | ||||||||||||||||||||
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2-Methylsuccinic acid (Standard) | 99.90% | 2-Methylsuccinic acid (Standard) is the analytical standard of 2-Methylsuccinic acid. This product is intended for research and analytical applications. 2-Methylsuccinic acid is a normal metabolite in human fluids and the main biochemical measurable features in ethylmalonic encephalopathy. | ||||||||||||||||||||
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Sodium malonate hydrate | 99.87% | Sodium malonate hydrate is a complexing agent for the determination of beryllium and copper. Sodium malonate hydrate is a kind of biological materials or organic compounds that are widely used in life science research. | ||||||||||||||||||||
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2-Methylpentanedioic acid (Standard) | ≥98% | 2-Methylpentanedioic acid (Standard) is the analytical standard of 2-Methylpentanedioic acid. This product is intended for research and analytical applications. 2-Methylpentanedioic acid is a metabolite of succinic acid, a citric acid cycle intermediate. | ||||||||||||||||||||
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β-Glutamic acid | 99.80% | β-Glutamic acid (3-Aminopentanedioic acid) is aβ amino acid. | ||||||||||||||||||||
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