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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
proteinase 3 (PR3)
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "proteinase 3 (PR3)" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-P70509
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PRTN3; Neutrophil proteinase 4; proteinase 3; Leukocyte proteinase 3; AGP7; Wegener Autoantigen; PR-3; C-ANCA Antigen; P29; NP-4; Myeloblastin; MBN; C-ANCA; PR3; ACPA; Azurophil Granule Protein 7; MBT; CANCA; Wegener Granulomatosis Autoantigen; NP4; Serin
Species:
Human
Source:
HEK293
Target:
Research Areas:
Neutrophil elastase inhibitor 5 is an inhibitor of human neutrophil elastase (HNE), proteinase 3 (PR3) and sirt2, with IC50 values of 4.91, 20.69 and 2.42 μM, respectively. Neutrophil elastase inhibitor 5 inhibits superoxide anion production and elastase release in human neutrophils. Neutrophil elastase inhibitor 5 can be used for the research of neutrophil inflammatory diseases .
Cathepsin C is a lysosomal cysteine protease essential for catalytic activation of many serine proteases, including proteinase 3 (PR3), neutrophil elastase (NE), cathepsin G (CTSG), granzyme A/B/C, and mast cell chymase .
Cat. No.: HY-163411
Target:
Research Areas:
Neutrophil elastase inhibitor 6 is a dual inhibitor of human neutrophil elastase (HNE) and proteinase 3 (PR3), with high selectivity for cathepsin G. Neutrophil elastase inhibitor 6 can be used in the research of chronic neutrophilic inflammatory diseases .
Cat. No.: HY-P10461
CAS No.: 1042405-14-0
Target:
Research Areas:
Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp is a fluorescent FRET substrate for proteinase 3 (PR3) with selectivity over neutrophil elastase and cathepsin G. Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp is cleaved by active PR3 to generate a detectable fluorescent signal, which is used to quantify the enzymatic activity of PR3, the concentration of free or membrane-bound PR3, and the PR3 activity on activated human neutrophils. Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp can be applied in studies related to lung ischemia-reperfusion injury, inflammatory diseases, and other relevant conditions .
Cat. No.: HY-P5459
Target:
Research Areas:
Elafin(human) is a serine protease inhibitory peptide that potently inhibits human neutrophil elastase (HLE) and human proteinase 3 (PR3). Elafin(human) forms a substrate-like, competitive and fully reversible complex with HLE at a 1:1 stoichiometric ratio, with a Ki of 0.17 nM. Elafin(human) inhibits PR3-mediated degradation of elastin-FITC, with an IC50 of 9.5 nM. Elafin(human) can be used in studies of neutrophil serine proteases, elastin degradation and inflammation-related tissue damage
Cat. No.: HY-P70509A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PRTN3; Neutrophil proteinase 4; proteinase 3; Leukocyte proteinase 3; AGP7; Wegener Autoantigen; PR-3; C-ANCA Antigen; P29; NP-4; Myeloblastin; MBN; C-ANCA; PR3; ACPA; Azurophil Granule Protein 7; MBT; CANCA; Wegener Granulomatosis Autoantigen; NP4; Serin
Species:
Human
Source:
HEK293
Cat. No.: HY-P76552
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PRTN3; Neutrophil proteinase 4; proteinase 3; Leukocyte proteinase 3; AGP7; Wegener Autoantigen; PR-3; C-ANCA Antigen; P29; NP-4; Myeloblastin; MBN; C-ANCA; PR3; ACPA; Azurophil Granule Protein 7; MBT; CANCA; Wegener Granulomatosis Autoantigen; NP4; Serin
Species:
Human
Source:
HEK293
Cat. No.: HY-P86686
Synonyms: ACPA; AGP 7; AGP7; AGP7 serine proteinase; Azurophil Granule Protein 7; C ANCA antigen; C-ANCA antigen; EC 3.4.21.76; Leukocyte proteinase 3; MBN; MBT WEGENER AUTOANTIGEN; Myeloblastin; Neutrophil proteinase 4; NP 4; NP-4; NP4; P29; PR 3; PR-3; proteinase3; PRTN 3; Prtn3; PRTN3_HUMAN; Serine proteinase neutrophil Wegener granulomatosis autoantigen; Wegener autoantigen.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
