3020696-44-7
3020696-44-7
Chemical Structure
Neutrophil elastase inhibitor 5
- CAS No.: 3020696-44-7
- Formula:C24H18N4O4
- Molecular Weight:426.42
InChIKey: SYTDKDNZPVIALG-IJOGZLALSA-N
SMILES: OC([C@H](C1=CC=CC=C1)NC(C2=NC=CC=C2/N=N/C3=C(C=CC=C4)C4=CC=C3O)=O)=O
Biological Activity: Neutrophil elastase inhibitor 5 is an inhibitor of human neutrophil elastase (HNE), proteinase 3 (PR3) and sirt2, with IC50 values of 4.91, 20.69 and 2.42 μM, respectively. Neutrophil elastase inhibitor 5 inhibits superoxide anion production and elastase release in human neutrophils. Neutrophil elastase inhibitor 5 can be used for the research of neutrophil inflammatory diseases[1].
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Neutrophil elastase inhibitor 5 | 95.74% | Neutrophil elastase inhibitor 5 is an inhibitor of human neutrophil elastase (HNE), proteinase 3 (PR3) and sirt2, with IC50 values of 4.91, 20.69 and 2.42 μM, respectively. Neutrophil elastase inhibitor 5 inhibits superoxide anion production and elastase release in human neutrophils. Neutrophil elastase inhibitor 5 can be used for the research of neutrophil inflammatory diseases. | ||||||||||||||||||||
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