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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
57 Results for "
quinoxalines
" in MedChemExpress (MCE) Product Catalog:
Products (57)
57 Results for "quinoxalines" in MCE Product Catalog:
67
67 Publications Verification
Synonyms: AKTi-1/2
Research Areas:
AKT inhibitor VIII (AKTi-1/2) is a cell-permeable quinoxaline compound that has been shown to potently, selectively, allosterically, and reversibly inhibit Akt1, Akt2, and Akt3 activity with IC50s of 58 nM, 210 nM, and 2119 nM, respectively.
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DNQX (FG 9041), a quinoxaline derivative, is a selective, potent competitive non-NMDA glutamate receptor antagonist (IC50s = 0.5, 2 and 40 μM for AMPA, kainate and NMDA receptors, respectively) .
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DNQX (FG 9041) disodium salt, a quinoxaline derivative, is a selective, potent competitive non-NMDA glutamate receptor antagonist (IC50s = 0.5, 2 and 40 μM for AMPA, kainate and NMDA receptors, respectively) .
1
Target:
1
1 Cited Publications
Cat. No.: HY-21210
CAS No.: 32602-11-2
6-Quinoxalinecarboxylic acid, 2,3-bis(bromomethyl)-, derived from 2,3-Bis(bromomethyl)quinoxaline, shows antibacterial activity .
1
1 Cited Publications
Cat. No.: HY-W028714
CAS No.: 32387-96-5
Target:
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2,3-Diphenylquinoxaline-6-carboxylic acid is used for end-capping in the synthesis of AB2 monomers, which facilitates the synthesis and chain-end modification of hyperbranched polymers containing alternating quinoxaline and benzoxazole repeating units .
Cat. No.: HY-N7427
CAS No.: 42015-38-3
Target:
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AZ3391 is a potent inhibitor of PARP. AZ3391 is a quinoxaline derivative. PARP family of enzymes play an important role in a number of cellular processes, such as replication, recombination, chromatin remodeling, and DNA damage repair. AZ3391 has the potential for the research of diseases and conditions occurring in tissues in the central nervous system, such as the brain and spinal cord (extracted from patent WO2021260092A1, compound 23) .
Cat. No.: HY-162088
CAS No.: 2241311-72-6
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DW71177 is a novel [1,2,4]triazolo[4,3-a] quinoxaline-based potent and BD1-Selective BET inhibitor, and can be used for study of acute myeloid leukemia .
Cat. No.: HY-W094511
CAS No.: 13874-02-7
Synonyms: Gold chloride sodium dihydrate
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2,3-Di(furan-2-yl)quinoxaline (Compound 5) is a quinoxaline exhibiting blue fluorescence. 2,3-Di(furan-2-yl)quinoxaline is cell permeable and sufficiently bright at a micromolar concentration (1.5 μM) .
Cat. No.: HY-120679
CAS No.: 157435-10-4
Synonyms: NSC 697887
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XK469 (NSC 697887) is a quinoxaline-based topoisomerase II inhibitor. XK469 exhibits antiproliferative activity against neuroblastoma cells. XK469 can be used in the research of neuroblastoma .
Cat. No.: HY-W007431
CAS No.: 36692-49-6
Cat. No.: HY-W017519
CAS No.: 1196-57-2
Synonyms: Quinoxalin-2-one
Target:
Research Areas:
2-Quinoxalinol (2-hydroxyquinoxaline) is a 2-hydroxylated quinoxaline that possesses photocatalytic activity and interacts with various compounds, such as antioxidant vitamins and aromatic metabolites, including neurotransmitters and the pineal hormone melatonin .
Cat. No.: HY-W700103
CAS No.: 1216997-87-3
Cat. No.: HY-W010865
CAS No.: 67174-25-8
Cat. No.: HY-150552
CAS No.: 2366264-18-6
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JNK3 inhibitor-2 is a potent and selective JNK3 inhibitor with IC50 values of >100, >100, 0.25 µM for JNK1, JNK2, JNK3, respectively. JNK3 inhibitor-2 shows DDR1 and EGFR (T790M, L858R) inhibition .
Cat. No.: HY-77982
CAS No.: 164329-39-9
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Research Areas:
Ethyl 1,8-dimethyl-4-oxo-4,5-dihydroimidazo[1,2-a]quinoxaline-2-carboxylate is a drug intermediate for synthesis of various active compounds.
Cat. No.: HY-20012
CAS No.: 230615-70-0
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8-(Trifluoroacetyl)-7,8,9,10-tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxaline is a drug intermediate for synthesis of various active compounds.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
