2 Results for "

rat STING

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "rat STING" in MCE Product Catalog:

  • Targets Recommended:
Cat. No.: HY-160406
CAS No.: 2332803-84-4
SNX281 is a selective STING agonist, with IC50 values of 4.1, 4.5, 10.7, and 3.7 μM against human, mouse, rat, and monkey STING, respectively. SNX281 undergoes homodimerization at the STING binding site, triggering a conformational shift of STING from an inactive open state to an active closed state, thereby driving downstream STING-dependent signaling pathways. SNX281 induces type I interferons, IFN-β, TNF-α, IL-6, cytokine release, T cell responses, and long-lasting immune memory. SNX281 exhibits anti-tumor activity and is applicable to research related to colorectal cancer, melanoma, advanced solid tumors, lymphoma, and ovarian cancer .
loading...
    loading...
Cat. No.: HY-RS13918
Research Areas:  

Others

Sting1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Sting1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...