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Results for "

rat STING

" in MedChemExpress (MCE) Product Catalog:

2

Inhibitors & Agonists

1

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-160406
    SNX281

    		STING IFNAR Interleukin Related Inflammation/Immunology Cancer
    SNX281 is a selective STING agonist, with IC50 values of 4.1, 4.5, 10.7, and 3.7 μM against human, mouse, rat, and monkey STING, respectively. SNX281 undergoes homodimerization at the STING binding site, triggering a conformational shift of STING from an inactive open state to an active closed state, thereby driving downstream STING-dependent signaling pathways. SNX281 induces type I interferons, IFN-β, TNF-α, IL-6, cytokine release, T cell responses, and long-lasting immune memory. SNX281 exhibits anti-tumor activity and is applicable to research related to colorectal cancer, melanoma, advanced solid tumors, lymphoma, and ovarian cancer .
    SNX281
  • HY-RS13918
    Sting1 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Sting1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Sting1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Sting1 Rat Pre-designed siRNA Set A
    Sting1 Rat Pre-designed siRNA Set A

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