4 Results for "

rat pheochromocytoma PC12 cells

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "rat pheochromocytoma PC12 cells" in MCE Product Catalog:

Cat. No.: HY-117517
CAS No.: 141731-76-2
NG-012, potentiator of nerve growth factor (NGF), were isolated from the culture broth of Penicillium verruculosum F-4542. NG-012 potentiates the neurite outgrowth induced by NGF in rat pheochromocytoma cell line (PC12) .
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Cat. No.: HY-N14417
CAS No.: 253450-08-7
Target:  

Others

Indocarbazostatin against Neurite outgrowth induced by NGF is 6 nM in rat pheochromocytoma PC12 cells .
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Cat. No.: HY-N14424
CAS No.: 334831-87-7
Target:  

Others

Indocarbazostatin B against Neurite outgrowth induced by NGF is 24 nM in rat pheochromocytoma PC12 cells .
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Cat. No.: HY-P11313
Synonyms: rat chromogranin A367–387
Target:  

nAChR Akt

Research Areas:  

Cardiovascular Disease

Catestatin (rat) (Rat chromogranin A367–387) is a potent, reversible, noncompetitive, and noncooperative nicotinic cholinergic antagonist derived from chromogranin A (A367-387). Catestatin (rat) inhibits norepinephrine release in rat PC12 pheochromocytoma cells (IC50 = 1.2 μM), and blocks desensitization of norepinephrine release (IC50 = 0.62 μM). Catestatin (rat) exerts antiadrenergic effects through the endothelial PI3K-AKT-eNOS pathway in rat papillary muscles and isolated cardiomyocytes. Catestatin (rat) maintains mitochondrial membrane potential in I/R cardiomyocytes and increases phosphorylation of AKT at S473, GSK3β at S9, PLB at T17, and eNOS at S1179. Catestatin (rat) reverses desensitization of 22Na + uptake. Catestatin (rat) can be used for the study of nicotinic cholinergic receptor regulation and catecholamine release control mechanisms .
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