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Results for "

semen

" in MedChemExpress (MCE) Product Catalog:

By Targets:	11β-HSD (2) Akt (2) AMPK (2) Apoptosis (3) Autophagy (2) Bacterial (2) Biochemical Assay Reagents (1) Caspase (2) Dopamine Receptor (1) Drug Derivative (3) Drug Intermediate (1) Drug Isomer (1) Drug Metabolite (1) EBV (1) Endogenous Metabolite (5) ERK (2) Ferroptosis (2) Fluorescent Dye (1) Fungal (1) GABA Receptor (2) HIV (2) Keap1-Nrf2 (2) p38 MAPK (2) PARP (2) PI3K (2) Prostaglandin Receptor (2) Reference Standards (5) STING (2) VEGFR (2) Xanthine Oxidase (1)
By Research Areas:	Cancer (7) Cardiovascular Disease (3) Infection (3) Inflammation/Immunology (5) Metabolic Disease (14) Neurological Disease (6)

By Targets:

11β-HSD (2)

Akt (2)

AMPK (2)

Apoptosis (3)

Autophagy (2)

Bacterial (2)

Biochemical Assay Reagents (1)

Caspase (2)

Dopamine Receptor (1)

Drug Derivative (3)

Drug Intermediate (1)

Drug Isomer (1)

Drug Metabolite (1)

EBV (1)

Endogenous Metabolite (5)

ERK (2)

Ferroptosis (2)

Fluorescent Dye (1)

Fungal (1)

GABA Receptor (2)

HIV (2)

Keap1-Nrf2 (2)

p38 MAPK (2)

PARP (2)

PI3K (2)

Prostaglandin Receptor (2)

Reference Standards (5)

STING (2)

VEGFR (2)

Xanthine Oxidase (1)

By Research Areas:

Cancer (7)

Cardiovascular Disease (3)

Infection (3)

Inflammation/Immunology (5)

Metabolic Disease (14)

Neurological Disease (6)

Inhibitors & Agonists

Screening Libraries

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0659

Jujuboside A 4 Publications Verification	GABA Receptor	Neurological Disease
Jujuboside A is a glycoside extracted from Semen Ziziphi Spinosae, a Chinese herbal medicine used to treat insomnia and anxiety.

HY-N0660

Jujuboside B	Apoptosis PARP Caspase AMPK Autophagy VEGFR Keap1-Nrf2 STING 11β-HSD Ferroptosis PI3K Akt p38 MAPK ERK	Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Jujuboside B is a bioactive saponin component isolated from Ziziphi Spinosae Semen (sour jujube seed), with oral efficacy and blood-brain barrier permeability. Jujuboside B induces acute leukemia cell death and drives necroptosis apoptosis by activating the RIPK1/RIPK3/MLKL pathway. Jujuboside B upregulates the expression of NOXA, PARP and caspase-3, activates AMPK, inhibits the proliferation of breast cancer cells, and induces cell apoptosis and autophagy. Jujuboside B inhibits angiogenesis and tumor growth by blocking the VEGFR-2 signaling pathway. Jujuboside B alleviates liver injury in mice by regulating the Nrf2-STING signaling pathway . Jujuboside B alleviates liver injury by regulating anti-inflammatory responses and downregulating the expression of 11β-HSD2. Jujuboside B induces ferroptosis and overcomes radioresistance in non-small cell lung cancer via the PPARγ-ATF3-Gpx4 signaling pathway. Jujuboside B exerts inhibitory effects on platelet aggregation. Jujuboside B inhibits febrile seizures by suppressing the activity of AMPA receptors. Jujuboside B reverses chronic unpredictable mild stress-promoted tumor progression by blocking the PI3K/Akt and MAPK/ERK pathways and dephosphorylating CREB signaling. Jujuboside B is applicable to related studies on acute leukemia, breast cancer, PM_2.5-induced lung injury, hepatotoxicity, liver injury, colorectal cancer, non-small cell lung cancer, thromboembolic diseases, cardiovascular diseases associated with high platelet aggregation, febrile seizures, and depressive-like phenotypes .

HY-N12326

Multiflorin A	Bacterial	Others
Multiflorin A is an active ingredient derived from Pruni semen. Multiflorin A has laxative activity. Multiflorin A inhibits intestinal glucose absorption and promotes bacterial metabolism .

HY-113220

Monoisobutyl phthalic acid	Endogenous Metabolite	Metabolic Disease
Monoisobutyl phthalic acid is a phthalate metabolite that is in human semen and in meconium.

HY-N1444

Complanatuside	Others	Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Complanatuside is a flavonoid found in the traditional Chinese medicine Semen Astragali Complanati.

HY-103470

K114	Fluorescent Dye	Others
K114, a fluorescent Congo Red analogue, binds tightly to amyloid fibrils with an EC₅₀ of 20-30 nM . K114 is an efficient detector of semen-derived enhancer of virus infection (SEVI) .

HY-113220S

Monoisobutyl phthalic acid-d4	Endogenous Metabolite	Metabolic Disease
Monoisobutyl phthalic acid-d₄ is the deuterium labeled Monoisobutyl phthalic acid . Monoisobutyl phthalic acid is a phthalate metabolite that is in human semen and in meconium .

HY-N7628

Cassiaside C Toralactone 9-O-β-D-gentiobioside	Endogenous Metabolite	Metabolic Disease
Cassiaside C (Toralactone 9-O-β-D-gentiobioside) is a naphthopyrone isolated from the seed of Cassia tora and has inhibitory activity on advanced glycation end products (AGE) formation in vitro .

HY-133860

Chrysoobtusin	Drug Derivative	Others
Chrysoobtusin is an anthraquinone derivative isolated from Semen Cassiae. Semen Cassiae has long been used to protect liver, brighten eyes, and relieve constipation .

HY-N7919

Celosin H 1 Publications Verification	Others	Metabolic Disease
Celosin H is a hepatoprotective triterpenoid saponin that can be isolated from Celosiae Semen .

HY-N12277

Celosin K	Apoptosis	Neurological Disease
Celosin K (compound 8) can be isolated from the seeds of Semen Celosiae. Celosin K is a potent inhibitor of neuron injury elicited by t-BHP. Celosin K inhibits oxidative stress and apoptosis, and acts of autophagy .

HY-15130R

DL-O-Phosphoserine (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease
Jujuboside A (Standard) is the analytical standard of Jujuboside A. This product is intended for research and analytical applications. Jujuboside A is a glycoside extracted from Semen Ziziphi Spinosae, a Chinese herbal medicine used to treat insomnia and anxiety.

HY-NP002C

Rabbit Serum Albumin (globulin free)	Biochemical Assay Reagents	Inflammation/Immunology
Rabbit Serum Albumin (globulin free) is a plasma protein derived from rabbits. Rabbit Serum Albumin (globulin-free) can stereoselectively bind to a variety of bioactive molecules. Rabbit Serum Albumin (globulin free) acts as the allergen Ory c RSA with cross-reactivity to other mammalian serum albumins. Rabbit Serum Albumin (globulin free) can be used for the research of allergy .

HY-W096638

Glycerylphosphorylcholine	Drug Intermediate	Others
Glycerylphosphorylcholine is a precursor of free choline in mammalian semen .

HY-N4179

Aurantio-obtusin β-D-glucoside Glucoaurantio-obtusin	Others	Metabolic Disease
Aurantio-obtusin β-D-glucoside (Glucoaurantio-obtusin), isolated from Cassiae Semen (seeds of Cassia tora), is a glucoside of aurantio-obtusin .

HY-N2047

Jujuboside B1	Others	Others
Jujuboside B1, a dammarane-type triterpene oligoglycoside, is isolated from Ziziphi Spinosae Semen .

HY-158595

15(R),19(R)-Hydroxy prostaglandin F2α 15(R),19(R)-Hydroxy PGF2α	Drug Derivative	Others
15(R),19(R)-Hydroxy prostaglandin F2α (15(R),19(R)-Hydroxy PGF2α) is an analog of 19(R)-Hydroxy-prostaglandin F2α. 19(R)-Hydroxy-prostaglandin F2α (HY-N7857) is an ω-1 hydroxylase metabolite of PGF2α found in human semen .

HY-N10645

Rhamnocitrin 3-O-β-D-apiofuranosyl(1→2)-β-D-glucopyranoside	Others	Others
Rhamnocitrin 3-O-β-D-apiofuranosyl(1→2)-β-D-glucopyranoside is a flavonol O-glycoside, isolated from Astragali semen of leguminous plants .

HY-N7705

Isoescin Ie	Others	Others
Isoescin Ie is a derivative of Aescine in Aesculi Semen extract .

HY-N7706

Escin Ie	Others	Others
Escin Ie is a derivative of Aescine in Aesculi Semen extract .

HY-P5363A

PAP 248-286 acetate Prostatic acid phosphatase (248-286) acetate	HIV	Infection
PAP 248-286 (Prostatic acid phosphatase (248-286)) acetate is a biological active peptide. PAP (248-286) acetate is a semen-derived enhancer of viral infection (SEVI) factor found in semen. This peptide greatly increases HIV infection through enhanced virion attachment to target cells. .

HY-P5363

PAP 248-286 Prostatic acid phosphatase (248-286)	HIV	Infection
PAP 248-286 (Prostatic acid phosphatase (248-286)) is a biological active peptide. PAP (248-286) peptide is a semen-derived enhancer of viral infection (SEVI) factor found in semen. This peptide greatly increases HIV infection through enhanced virion attachment to target cells .

HY-N10597

5'''-O-Feruloyl complanatoside B	Others	Cardiovascular Disease Metabolic Disease Cancer
5'''-O-Feruloyl complanatoside B is isolated from Astragali Semen, the seeds of Astragalus Complanatus. Semen Astragali Complanati (SAC) include fatty acids, amino acids, polysaccharides, flavonoids, triterpene glycosides and trace elements; have been reported to involve in chronic diseases such as cardiovascular diseases, diabetes mellitus and cancers .

HY-N1444R

Complanatuside (Standard)	Reference Standards Others	Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Complanatuside (Standard) is the analytical standard of Complanatuside. This product is intended for research and analytical applications. Complanatuside is a flavonoid found in the traditional Chinese medicine Semen Astragali Complanati.

HY-P1940R

Maculosin (Standard) Cyclo(Tyr-Pro) (Standard)	Endogenous Metabolite Reference Standards Bacterial Fungal	Infection Cancer
Complanatuside (Standard) is the analytical standard of Complanatuside. This product is intended for research and analytical applications. Complanatuside is a flavonoid found in the traditional Chinese medicine Semen Astragali Complanati.

HY-W104467

(+/-)-Epicatechin (+/-)-Epicatechol; (+/-)-epi-Catechin	Xanthine Oxidase	Metabolic Disease
(+/-)-Epicatechin is a xanthine oxidase inhibitor with an IC₅₀ of 982.14 μM, and can be found in Semen Plantaginis (Plantago seed). (+/-)-Epicatechin can be used in research on diseases such as hyperuricemia and gout .

HY-N0659R

Jujuboside A (Standard)	Reference Standards GABA Receptor	Neurological Disease
Jujuboside A (Standard) is the analytical standard of Jujuboside A. This product is intended for research and analytical applications. Jujuboside A is a glycoside extracted from Semen Ziziphi Spinosae, a Chinese herbal medicine used to treat insomnia and anxiety.

HY-124521

Quinelorane LY163502 free base	Dopamine Receptor	Neurological Disease
Quinelorane (LY163502 free base) is a dopamine D2 receptor agonist. Quinelorane promotes semen ejaculation but inhibits penile erection in rats. Quinelorane can be used in the study of sexual dysfunction .

HY-N7857

19(R)-Hydroxy-prostaglandin F2α 19(R)-Hydroxy PGF2α	Drug Metabolite	Metabolic Disease
19(R)-Hydroxy-prostaglandin F2α (19(R)-hydroxy PGF2α) is an ω-1 hydroxylase metabolite of PGF2α found in human semen. The concentration of 19(R)-Hydroxy-PGFs compounds (F2α and F1α together) in fresh human semen is about 20 μg/mL. 19(R)-Hydroxy-prostaglandin F2α exhibits no activity at the FP receptor of the cat iris sphincter muscle at concentrations up to 1 μM.

HY-137574

19(R)-Hydroxy prostaglandin E1 19(R)-Hydroxy PGE1	Prostaglandin Receptor	Others
19(R)-Hydroxy prostaglandin E1 (19(R)-Hydroxy PGE1), the major prostaglandin in primate semen, is an agonist of EP1 and EP3 receptor subtypes and exhibits contractile activity on smooth muscle preparations .

HY-139120

19(R)-hydroxy Prostaglandin E2 19(R)-Hydroxy PGE2; 19(R)-OH PGE2	Prostaglandin Receptor	Metabolic Disease
19(R)-hydroxy Prostaglandin E2 (19(R)-hydroxy PGE2) is found in the semen of primates, including man. It is a potent smooth muscle relaxant and a selective agonist for the EP2 receptor. It has an EC₅₀ value of 200 nM for relaxing cat tracheal rings which express EP2 receptors.

HY-N19048

Semen ziziphi spinosae extract	Others	Others
Semen Ziziphi Spinosae Extract is derived from the dried seeds of Ziziphus jujuba Mill.var.spinosa, a plant of the Rhamnaceae family. The active ingredients include flavonoid glycosides, triterpenes, saponins and organic acids, etc.

HY-172571

15(R),19(R)-Hydroxy prostaglandin F1α 15(R),19(R)-Hydroxy PGF1α	Drug Derivative	Others
15(R),19(R)-Hydroxy prostaglandin F1α is a hydroxylated derivative of PGF1α, which is mainly found in the semen of some mammals .

HY-N18106

Amygdalinic acid	EBV	Cancer
Amygdalinic acid (Compound 3) is a glycoside. Amygdalinic acid can be isolated from Persicae Semen. Amygdalinic acid inhibits Epstein-Barr virus early antigen activation. Amygdalinic acid delays two-stage chemical carcinogenesis in mouse skin, reduces papilloma incidence .

HY-172572

15(R),19(R)-Hydroxy prostaglandin E1 15(R),19(R)-Hydroxy PGE1	Drug Isomer	Others
15(R),19(R)-Hydroxy prostaglandin E1 is a dihydroxy metabolite/stereoisomer of Prostaglandin E1 (HY-B0131). 15(R),19(R)-Hydroxy prostaglandin E1 is found in the semen of some mammals, especially primates .

HY-N0660R

Jujuboside B (Standard)	Reference Standards ERK p38 MAPK Akt PI3K 11β-HSD STING VEGFR Ferroptosis Autophagy Apoptosis Keap1-Nrf2 Caspase PARP AMPK	Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Jujuboside B (Standard) is the analytical standard of Jujuboside B. This product is intended for research and analytical applications. Jujuboside B is a bioactive saponin component isolated from Ziziphi Spinosae Semen (sour jujube seed), with oral efficacy and blood-brain barrier permeability. Jujuboside B induces acute leukemia cell death and drives necroptosis apoptosis by activating the RIPK1/RIPK3/MLKL pathway. Jujuboside B upregulates the expression of NOXA, PARP and caspase-3, activates AMPK, inhibits the proliferation of breast cancer cells, and induces cell apoptosis and autophagy. Jujuboside B inhibits angiogenesis and tumor growth by blocking the VEGFR-2 signaling pathway. Jujuboside B alleviates liver injury in mice by regulating the Nrf2-STING signaling pathway . Jujuboside B alleviates liver injury by regulating anti-inflammatory responses and downregulating the expression of 11β-HSD2. Jujuboside B induces ferroptosis and overcomes radioresistance in non-small cell lung cancer via the PPARγ-ATF3-Gpx4 signaling pathway. Jujuboside B exerts inhibitory effects on platelet aggregation. Jujuboside B inhibits febrile seizures by suppressing the activity of AMPA receptors. Jujuboside B reverses chronic unpredictable mild stress-promoted tumor progression by blocking the PI3K/Akt and MAPK/ERK pathways and dephosphorylating CREB signaling. Jujuboside B is applicable to related studies on acute leukemia, breast cancer, PM_2.5-induced lung injury, hepatotoxicity, liver injury, colorectal cancer, non-small cell lung cancer, thromboembolic diseases, cardiovascular diseases associated with high platelet aggregation, febrile seizures, and depressive-like phenotypes.

Cat. No.	Product Name

HY-L223

Antitussive and Antiasthmatic Traditional Chinese Medicine Active Compound Library	862 compounds
Antitussive and antiasthmatic method is a type of treatment strategy in traditional Chinese medicine, mainly used to alleviate symptoms such as coughing and asthma. These symptoms may be caused by various factors, such as: Bronchial asthma, chronic obstructive pulmonary disease, asthmatic bronchitis, cough-induced asthma, and others. Based on existing research in traditional Chinese medicine, many types of Chinese medicinal herbs showed antitussive and antiasthmatic effects. For example: Ardisiae Japonicae Herba, Ginkgo Semen, Amygdalus Communis Vas, Farfarae Flos, Viticis Cannabifoliae Fructus, Eriobotryae Folium etc. Therefore, the active ingredients derived from these traditional Chinese medicine have high medicinal value and have the potential to be developed into drugs for related diseases. MCE can provide 862 active ingredients that can be obtained from traditional Chinese medicine with antitussive and antiasthmatic functions, which can be applied to drug development and research on disease mechanisms.

Antitussive and Antiasthmatic Traditional Chinese Medicine Active Compound Library

862 compounds

Antitussive and antiasthmatic method is a type of treatment strategy in traditional Chinese medicine, mainly used to alleviate symptoms such as coughing and asthma. These symptoms may be caused by various factors, such as: Bronchial asthma, chronic obstructive pulmonary disease, asthmatic bronchitis, cough-induced asthma, and others. Based on existing research in traditional Chinese medicine, many types of Chinese medicinal herbs showed antitussive and antiasthmatic effects. For example: Ardisiae Japonicae Herba, Ginkgo Semen, Amygdalus Communis Vas, Farfarae Flos, Viticis Cannabifoliae Fructus, Eriobotryae Folium etc. Therefore, the active ingredients derived from these traditional Chinese medicine have high medicinal value and have the potential to be developed into drugs for related diseases.

MCE can provide 862 active ingredients that can be obtained from traditional Chinese medicine with antitussive and antiasthmatic functions, which can be applied to drug development and research on disease mechanisms.

HY-L224

Diarrhea-Related Traditional Chinese Medicine Active Compound Library	2,465 compounds
Diarrhea is a disease symptom, and the pathophysiologic basis of diarrhea is a disturbance in intestinal water and electrolyte balance, which may be due to increased secretion of osmotically active electrolytes (secretory diarrhea) or increased intake of osmotically active substances (osmotic diarrhea). Food poisoning, pathogenic bacterial infections, and intestinal-related diseases can all contribute to the development of diarrhea. Traditional Chinese Medicine (TCM) considers diarrhea to be a symptom of an imbalance in the body's systems, particularly related to the functions of the spleen and stomach. Spleen qi deficiency, dampness-heat, liver and spleen disharmony are closely related to diarrhea. Many types of Chinese herbs regulate the function of diarrhea, such as: Dysosmae Verspiellis Rhixoma Et Radix, Ginkgo Semen, Forsythiae Fructus, and Campsis Flos. MCE can provide 2,465 active monomers that can be obtained from TCM herbs with diarrhea-regulating functions, which can be applied to drug development and disease mechanism research.

Diarrhea-Related Traditional Chinese Medicine Active Compound Library

2,465 compounds

Diarrhea is a disease symptom, and the pathophysiologic basis of diarrhea is a disturbance in intestinal water and electrolyte balance, which may be due to increased secretion of osmotically active electrolytes (secretory diarrhea) or increased intake of osmotically active substances (osmotic diarrhea). Food poisoning, pathogenic bacterial infections, and intestinal-related diseases can all contribute to the development of diarrhea. Traditional Chinese Medicine (TCM) considers diarrhea to be a symptom of an imbalance in the body's systems, particularly related to the functions of the spleen and stomach. Spleen qi deficiency, dampness-heat, liver and spleen disharmony are closely related to diarrhea. Many types of Chinese herbs regulate the function of diarrhea, such as: Dysosmae Verspiellis Rhixoma Et Radix, Ginkgo Semen, Forsythiae Fructus, and Campsis Flos.

MCE can provide 2,465 active monomers that can be obtained from TCM herbs with diarrhea-regulating functions, which can be applied to drug development and disease mechanism research.

HY-L193

PBCRBS Traditional Chinese Medicine Compound Library	996 compounds
Since ancient times, promoting blood circulation for removing blood stasis (PBCRBS) has been one of the most popular research contents in the area of traditional Chinese medicine (TCM) and integrated medicine. Rhizoma, Persicae Semen, Carthami Flos, Curcumae Longae Rhizoma and so on are common TCM with PBCRBS characteristic. Studies have shown that the mechanism of action of PBCRBS TCM is to promote blood circulation (improving cardiovascular and cerebrovascular functions, physical and chemical properties of blood, platelet and coagulation system and other physiological functions) and remove blood stasis (anti-myocardial ischemia, cerebral ischemia, inhibition of platelet aggregation, anti-coagulation, anti-thrombosis, etc.). Not only that, PBCRBS TCM has anti-infection, inhibit inflammation, regulate immune function, inhibit immune response, inhibit abnormal tissue proliferation and other functions. Therefore, PBCRBS TCM has high research value in all- field disease research fields. MCE can supply 996 monomer component from more than a hundred sources of PBCRBS TCM, which can be used in TCM studies, drug development and mechanism-based studies.

PBCRBS Traditional Chinese Medicine Compound Library

996 compounds

Since ancient times, promoting blood circulation for removing blood stasis (PBCRBS) has been one of the most popular research contents in the area of traditional Chinese medicine (TCM) and integrated medicine. Rhizoma, Persicae Semen, Carthami Flos, Curcumae Longae Rhizoma and so on are common TCM with PBCRBS characteristic. Studies have shown that the mechanism of action of PBCRBS TCM is to promote blood circulation (improving cardiovascular and cerebrovascular functions, physical and chemical properties of blood, platelet and coagulation system and other physiological functions) and remove blood stasis (anti-myocardial ischemia, cerebral ischemia, inhibition of platelet aggregation, anti-coagulation, anti-thrombosis, etc.). Not only that, PBCRBS TCM has anti-infection, inhibit inflammation, regulate immune function, inhibit immune response, inhibit abnormal tissue proliferation and other functions. Therefore, PBCRBS TCM has high research value in all- field disease research fields.

MCE can supply 996 monomer component from more than a hundred sources of PBCRBS TCM, which can be used in TCM studies, drug development and mechanism-based studies.

K114	Fluorescent Dyes
K114, a fluorescent Congo Red analogue, binds tightly to amyloid fibrils with an EC₅₀ of 20-30 nM . K114 is an efficient detector of semen-derived enhancer of virus infection (SEVI) .

Rabbit Serum Albumin (globulin free)	Biochemical Assay Reagents
Rabbit Serum Albumin (globulin free) is a plasma protein derived from rabbits. Rabbit Serum Albumin (globulin-free) can stereoselectively bind to a variety of bioactive molecules. Rabbit Serum Albumin (globulin free) acts as the allergen Ory c RSA with cross-reactivity to other mammalian serum albumins. Rabbit Serum Albumin (globulin free) can be used for the research of allergy .

Cat. No.	Product Name	Target	Research Area

HY-P5363A

PAP 248-286 acetate Prostatic acid phosphatase (248-286) acetate	HIV	Infection
PAP 248-286 (Prostatic acid phosphatase (248-286)) acetate is a biological active peptide. PAP (248-286) acetate is a semen-derived enhancer of viral infection (SEVI) factor found in semen. This peptide greatly increases HIV infection through enhanced virion attachment to target cells. .

HY-P5363

PAP 248-286 Prostatic acid phosphatase (248-286)	HIV	Infection
PAP 248-286 (Prostatic acid phosphatase (248-286)) is a biological active peptide. PAP (248-286) peptide is a semen-derived enhancer of viral infection (SEVI) factor found in semen. This peptide greatly increases HIV infection through enhanced virion attachment to target cells .

HY-P1940R

Maculosin (Standard) Cyclo(Tyr-Pro) (Standard)	Endogenous Metabolite Reference Standards Bacterial Fungal	Infection Cancer
Complanatuside (Standard) is the analytical standard of Complanatuside. This product is intended for research and analytical applications. Complanatuside is a flavonoid found in the traditional Chinese medicine Semen Astragali Complanati.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0659

Jujuboside A 4 Publications Verification	Triterpenes Terpenoids Actaea dahurica Turcz. ex Fisch. & C. A. Mey. Plants Rhamnaceae Source Classification	GABA Receptor
Jujuboside A is a glycoside extracted from Semen Ziziphi Spinosae, a Chinese herbal medicine used to treat insomnia and anxiety.

HY-N0660

Jujuboside B	Cardiovascular Disease Triterpenes Structural Classification other families Classification of Application Fields Terpenoids Plants Disease Research Fields Source Classification	Apoptosis PARP Caspase AMPK Autophagy VEGFR Keap1-Nrf2 STING 11β-HSD Ferroptosis PI3K Akt p38 MAPK ERK
Jujuboside B is a bioactive saponin component isolated from Ziziphi Spinosae Semen (sour jujube seed), with oral efficacy and blood-brain barrier permeability. Jujuboside B induces acute leukemia cell death and drives necroptosis apoptosis by activating the RIPK1/RIPK3/MLKL pathway. Jujuboside B upregulates the expression of NOXA, PARP and caspase-3, activates AMPK, inhibits the proliferation of breast cancer cells, and induces cell apoptosis and autophagy. Jujuboside B inhibits angiogenesis and tumor growth by blocking the VEGFR-2 signaling pathway. Jujuboside B alleviates liver injury in mice by regulating the Nrf2-STING signaling pathway . Jujuboside B alleviates liver injury by regulating anti-inflammatory responses and downregulating the expression of 11β-HSD2. Jujuboside B induces ferroptosis and overcomes radioresistance in non-small cell lung cancer via the PPARγ-ATF3-Gpx4 signaling pathway. Jujuboside B exerts inhibitory effects on platelet aggregation. Jujuboside B inhibits febrile seizures by suppressing the activity of AMPA receptors. Jujuboside B reverses chronic unpredictable mild stress-promoted tumor progression by blocking the PI3K/Akt and MAPK/ERK pathways and dephosphorylating CREB signaling. Jujuboside B is applicable to related studies on acute leukemia, breast cancer, PM_2.5-induced lung injury, hepatotoxicity, liver injury, colorectal cancer, non-small cell lung cancer, thromboembolic diseases, cardiovascular diseases associated with high platelet aggregation, febrile seizures, and depressive-like phenotypes .

HY-N12326

Multiflorin A	Flavonoids Flavones Prunus humilis (Bge.) Sok. Rosaceae Plants Source Classification	Bacterial
Multiflorin A is an active ingredient derived from Pruni semen. Multiflorin A has laxative activity. Multiflorin A inhibits intestinal glucose absorption and promotes bacterial metabolism .

HY-113220

Monoisobutyl phthalic acid	Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Monoisobutyl phthalic acid is a phthalate metabolite that is in human semen and in meconium.

HY-N1444

Complanatuside	Cardiovascular Disease Flavonols Classification of Application Fields Metabolic Disease Plants Astragalus complanatus Monophenols Flavonoids Papilionaceae Phenols Inflammation/Immunology Disease Research Fields Source Classification	Others
Complanatuside is a flavonoid found in the traditional Chinese medicine Semen Astragali Complanati.

HY-N7628

Cassiaside C Toralactone 9-O-β-D-gentiobioside	Cassia tora (L.) Roxb. Monophenols Classification of Application Fields Leguminosae Phenols Metabolic Disease Plants Disease Research Fields Source Classification	Endogenous Metabolite
Cassiaside C (Toralactone 9-O-β-D-gentiobioside) is a naphthopyrone isolated from the seed of Cassia tora and has inhibitory activity on advanced glycation end products (AGE) formation in vitro .

HY-133860

Chrysoobtusin	Seeds of Cassia tora Linn. Quinones other families Classification of Application Fields Leguminosae Anthraquinones Other Diseases Phenols Polyphenols Plants Disease Research Fields Source Classification	Drug Derivative
Chrysoobtusin is an anthraquinone derivative isolated from Semen Cassiae. Semen Cassiae has long been used to protect liver, brighten eyes, and relieve constipation .

HY-N7919

Celosin H 1 Publications Verification	Structural Classification Celosia argentea Linn. Terpenoids Amaranthaceae Plants Pentacyclic Triterpenoids Source Classification	Others
Celosin H is a hepatoprotective triterpenoid saponin that can be isolated from Celosiae Semen .

HY-N12277

Celosin K	Triterpenes Structural Classification Celosia argentea Linn. Terpenoids Amaranthaceae Plants Pentacyclic Triterpenoids Source Classification	Apoptosis
Celosin K (compound 8) can be isolated from the seeds of Semen Celosiae. Celosin K is a potent inhibitor of neuron injury elicited by t-BHP. Celosin K inhibits oxidative stress and apoptosis, and acts of autophagy .

HY-15130R

DL-O-Phosphoserine (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
Jujuboside A (Standard) is the analytical standard of Jujuboside A. This product is intended for research and analytical applications. Jujuboside A is a glycoside extracted from Semen Ziziphi Spinosae, a Chinese herbal medicine used to treat insomnia and anxiety.

HY-N4179

Aurantio-obtusin β-D-glucoside Glucoaurantio-obtusin	Seeds of Cassia tora Linn. Quinones other families Classification of Application Fields Leguminosae Anthraquinones Phenols Polyphenols Metabolic Disease Plants Disease Research Fields Source Classification	Others
Aurantio-obtusin β-D-glucoside (Glucoaurantio-obtusin), isolated from Cassiae Semen (seeds of Cassia tora), is a glucoside of aurantio-obtusin .

HY-N2047

Jujuboside B1	Triterpenes other families Classification of Application Fields Terpenoids Other Diseases Plants Disease Research Fields Source Classification	Others
Jujuboside B1, a dammarane-type triterpene oligoglycoside, is isolated from Ziziphi Spinosae Semen .

HY-N10645

Rhamnocitrin 3-O-β-D-apiofuranosyl(1→2)-β-D-glucopyranoside	Flavonoids Flavones Leguminosae Astragalus caprinus L. Plants	Others
Rhamnocitrin 3-O-β-D-apiofuranosyl(1→2)-β-D-glucopyranoside is a flavonol O-glycoside, isolated from Astragali semen of leguminous plants .

HY-N7705

Isoescin Ie	Triterpenes Classification of Application Fields Terpenoids Hippocastanaceae Other Diseases Plants Disease Research Fields Aesculus chinensis var. wilsonii (Rehder) Turland & N. H. Xia Source Classification	Others
Isoescin Ie is a derivative of Aescine in Aesculi Semen extract .

HY-N7706

Escin Ie	Triterpenes other families Classification of Application Fields Terpenoids Other Diseases Plants Disease Research Fields Source Classification	Others
Escin Ie is a derivative of Aescine in Aesculi Semen extract .

HY-N10597

5'''-O-Feruloyl complanatoside B	Flavonoids Leguminosae Plants Other Flavonoids Phyllolobium chinense Fisch. ex DC.	Others
5'''-O-Feruloyl complanatoside B is isolated from Astragali Semen, the seeds of Astragalus Complanatus. Semen Astragali Complanati (SAC) include fatty acids, amino acids, polysaccharides, flavonoids, triterpene glycosides and trace elements; have been reported to involve in chronic diseases such as cardiovascular diseases, diabetes mellitus and cancers .

HY-N1444R

Complanatuside (Standard)	Flavonols Structural Classification Monophenols Flavonoids Papilionaceae Phenols Plants Astragalus complanatus Source Classification	Reference Standards Others
Complanatuside (Standard) is the analytical standard of Complanatuside. This product is intended for research and analytical applications. Complanatuside is a flavonoid found in the traditional Chinese medicine Semen Astragali Complanati.

HY-P1940R

Maculosin (Standard) Cyclo(Tyr-Pro) (Standard)	Alkaloids Monophenols Microorganisms Pyrrole Alkaloids Phenols Source Classification	Endogenous Metabolite Reference Standards Bacterial Fungal
Complanatuside (Standard) is the analytical standard of Complanatuside. This product is intended for research and analytical applications. Complanatuside is a flavonoid found in the traditional Chinese medicine Semen Astragali Complanati.

HY-W104467

(+/-)-Epicatechin (+/-)-Epicatechol; (+/-)-epi-Catechin	Malvaceae Flavonoids Flavanols Phenols Polyphenols Plants Scaphium wallichii Source Classification	Xanthine Oxidase
(+/-)-Epicatechin is a xanthine oxidase inhibitor with an IC₅₀ of 982.14 μM, and can be found in Semen Plantaginis (Plantago seed). (+/-)-Epicatechin can be used in research on diseases such as hyperuricemia and gout .

HY-N0659R

Jujuboside A (Standard)	Triterpenes Structural Classification Terpenoids Actaea dahurica Turcz. ex Fisch. & C. A. Mey. Plants Rhamnaceae Source Classification	Reference Standards GABA Receptor
Jujuboside A (Standard) is the analytical standard of Jujuboside A. This product is intended for research and analytical applications. Jujuboside A is a glycoside extracted from Semen Ziziphi Spinosae, a Chinese herbal medicine used to treat insomnia and anxiety.

HY-N19048

Semen ziziphi spinosae extract	Structural Classification Extract	Others
Semen Ziziphi Spinosae Extract is derived from the dried seeds of Ziziphus jujuba Mill.var.spinosa, a plant of the Rhamnaceae family. The active ingredients include flavonoid glycosides, triterpenes, saponins and organic acids, etc.

HY-N18106

Amygdalinic acid	Structural Classification Prunus persica L. Ketones, Aldehydes, Acids Rosaceae Plants Source Classification	EBV
Amygdalinic acid (Compound 3) is a glycoside. Amygdalinic acid can be isolated from Persicae Semen. Amygdalinic acid inhibits Epstein-Barr virus early antigen activation. Amygdalinic acid delays two-stage chemical carcinogenesis in mouse skin, reduces papilloma incidence .

HY-N0660R

Jujuboside B (Standard)	Triterpenes Structural Classification other families Terpenoids Plants Source Classification	Reference Standards ERK p38 MAPK Akt PI3K 11β-HSD STING VEGFR Ferroptosis Autophagy Apoptosis Keap1-Nrf2 Caspase PARP AMPK
Jujuboside B (Standard) is the analytical standard of Jujuboside B. This product is intended for research and analytical applications. Jujuboside B is a bioactive saponin component isolated from Ziziphi Spinosae Semen (sour jujube seed), with oral efficacy and blood-brain barrier permeability. Jujuboside B induces acute leukemia cell death and drives necroptosis apoptosis by activating the RIPK1/RIPK3/MLKL pathway. Jujuboside B upregulates the expression of NOXA, PARP and caspase-3, activates AMPK, inhibits the proliferation of breast cancer cells, and induces cell apoptosis and autophagy. Jujuboside B inhibits angiogenesis and tumor growth by blocking the VEGFR-2 signaling pathway. Jujuboside B alleviates liver injury in mice by regulating the Nrf2-STING signaling pathway . Jujuboside B alleviates liver injury by regulating anti-inflammatory responses and downregulating the expression of 11β-HSD2. Jujuboside B induces ferroptosis and overcomes radioresistance in non-small cell lung cancer via the PPARγ-ATF3-Gpx4 signaling pathway. Jujuboside B exerts inhibitory effects on platelet aggregation. Jujuboside B inhibits febrile seizures by suppressing the activity of AMPA receptors. Jujuboside B reverses chronic unpredictable mild stress-promoted tumor progression by blocking the PI3K/Akt and MAPK/ERK pathways and dephosphorylating CREB signaling. Jujuboside B is applicable to related studies on acute leukemia, breast cancer, PM_2.5-induced lung injury, hepatotoxicity, liver injury, colorectal cancer, non-small cell lung cancer, thromboembolic diseases, cardiovascular diseases associated with high platelet aggregation, febrile seizures, and depressive-like phenotypes.

Cat. No.	Product Name	Chemical Structure

HY-113220S

Monoisobutyl phthalic acid-d4
Monoisobutyl phthalic acid-d₄ is the deuterium labeled Monoisobutyl phthalic acid . Monoisobutyl phthalic acid is a phthalate metabolite that is in human semen and in meconium .

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