62 Results for "

small intestine

" in MedChemExpress (MCE) Product Catalog:
Products (62)

62 Results for "small intestine" in MCE Product Catalog:

6
6 Publications Verification
Cat. No.: HY-N0169
CAS No.: 83-49-8
Synonyms: HDCA
Hyodeoxycholic acid is a secondary bile acid formed in the small intestine by the gut flora, and acts as a TGR5 (GPCR19) agonist, with an EC50 of 31.6 µM in CHO cells.
loading...
    loading...
6
6 Publications Verification
Cat. No.: HY-B0411
CAS No.: 57808-66-9
Synonyms: R33812
Target:  

Dopamine Receptor

Research Areas:  

Neurological Disease

Domperidone (R33812) is an orally active and selective dopamine-2 receptor antagonist. Domperidone acts as an antiemetic and a prokinetic agent through its effects on the chemoreceptor trigger zone and motor function of the stomach and small intestine .
loading...
    loading...
6
6 Publications Verification
Cat. No.: HY-B0411A
CAS No.: 83898-65-1
Synonyms: R33812 monomaleate
Target:  

Dopamine Receptor

Research Areas:  

Neurological Disease

Domperidone (R33812) monomaleate is an orally active and selective dopamine-2 receptor antagonist. Domperidone monomaleate acts as an antiemetic and a prokinetic agent through its effects on the chemoreceptor trigger zone and motor function of the stomach and small intestine .
loading...
    loading...
6
6 Publications Verification
Cat. No.: HY-N0169A
CAS No.: 10421-49-5
Synonyms: HDCA sodium
Hyodeoxycholic acid sodium is a secondary bile acid formed in the small intestine by the gut flora, and acts as a TGR5 (GPCR19) agonist, with an EC50 of 31.6 µM in CHO cells .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P2802
CAS No.: 9001-42-7
Synonyms: α-D-Glucosidase, Yeast
Target:  

Glycosidase

Research Areas:  

Metabolic Disease

α-Glucosidase, Yeast (α-D-Glucosidase, Yeast), a carbohydrate hydrolyzing enzyme, catalyzes the liberation of α-glucose from the non-reducing end of the substrate. α-Glucosidase can facilitate the absorption of glucose by the small intestine. Inhibition of α-Glucosidase is an effective management of non-insulin-dependent diabetes mellitus (NIDDM) .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-B1278
CAS No.: 58-95-7
Synonyms: D-Vitamin E acetate
D-α-Tocopherol acetate (D-Vitamin E acetate) can be hydrolyzed to d-alpha-tocopherol (VE) and absorbed in the small intestine .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-111956B
CAS No.: 2703746-41-0
Purity:  98.77%
Target:  

Fluorescent Dye

Research Areas:  

Cancer

D-Ala-Lys-AMCA hydrochloride is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA hydrochloride may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. D-Ala-Lys-AMCA hydrochloride can be used for characterizing PEPT1-specific substrates or inhibitors (Ex/Em = 390/480 nm) .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P1276A
Synonyms: Neurokinin-2 receptor antagonist TFA
Target:  

Neurokinin Receptor

Research Areas:  

Endocrinology

Men 10376 TFA is a selective tachykinin NK-2 receptor antagonist, with a Ki of 4.4 μM for rat small intestine NK-2 receptor .
loading...
    loading...
Cat. No.: HY-N15135
CAS No.: 9040-27-1
Arabinoxylan Medium viscosity is an orally active Dectin-1 splice variant modulator, glucose absorption inhibitor, and chyme viscosity enhancer. Arabinoxylan Medium viscosity inhibits particulate β-glucan-induced Dectin-1A activation and mildly suppresses Dectin-1B activation. In human dendritic cells stimulated with particulate β-glucan, Arabinoxylan Medium viscosity reduces the production of IL-10 and TNF-α, and increases the production of IL-4 and IL-23. Arabinoxylan Medium viscosity also supports antifungal immune responses without activating TLR2, TLR4 or TLR5, and does not induce cytokine production when used to stimulate human dendritic cells alone. Arabinoxylan Medium viscosity increases small intestinal chyme viscosity, gets degraded in the large intestine to produce short-chain fatty acids, reduces glucose absorption and insulin response, and improves glucose homeostasis. Arabinoxylan Medium viscosity supports microbial fermentation and the growth of beneficial microbiota in the gastrointestinal tract, prevents bile acid reabsorption, and delays starch digestion. Arabinoxylan Medium viscosity can be used in research related to type 2 diabetes, impaired glucose tolerance, and metabolic syndrome .
loading...
    loading...
Cat. No.: HY-B1731
CAS No.: 118-55-8
Target:  

Bacterial

Research Areas:  

Neurological Disease

Phenyl salicylate (PS) has antibacterial activity when hydrolyzed in small intestine and is often used as nervous system inhibitor and intestinal preservative .
loading...
    loading...
Cat. No.: HY-P2990
CAS No.: 9014-74-8
Synonyms: TMPRSS15
Target:  

Ser/Thr Protease

Research Areas:  

Metabolic Disease

Enteropeptidase (TMPRSS15), a type II transmembrane serine protease and a physiological activator of trypsinogen. Enteropeptidase is associated with the brush border membrane (BBM) of the enterocytes in the upper small intestine. Trypsinogen is the primary substrate for Enteropeptidase. Enteropeptidase is involved in digestion in humans and animals .
loading...
    loading...
Cat. No.: HY-154912
CAS No.: 1775330-54-5
Purity:  98.32%
Target:  

Chloride Channel

Research Areas:  

Inflammation/Immunology

PAT1inh-B01 is a selective SLC26A6 inhibitor. PAT1inh-B01 inhibits PAT1 (a Cl -/HCO3 - exchanger)-mediated anion exchange (IC50: 350 nM). PAT1inh-B01 blocks fluid absorption in small intestine. PAT1inh-B01 can be used for research of small intestinal hyposecretory disorders .
loading...
    loading...
Cat. No.: HY-N0169R
CAS No.: 83-49-8
Synonyms: HDCA (Standard)
Hyodeoxycholic acid (Standard) is the analytical standard of Hyodeoxycholic acid. This product is intended for research and analytical applications. Hyodeoxycholic acid is a secondary bile acid formed in the small intestine by the gut flora, and acts as a TGR5 (GPCR19) agonist, with an EC50 of 31.6 µM in CHO cells.
loading...
    loading...
Cat. No.: HY-P2317
CAS No.: 125667-96-1
Research Areas:  

Infection

Cecropin P1, porcine is an antibacterial peptide that can be isolated from the upper part of the small intestine of the pig. Cecropin P1, porcine shows antibacterial activity against Gram-negative bacteria. Cecropin P1, porcine shows antiviral activity and inhibits PRRSV infection .
loading...
    loading...
Cat. No.: HY-P5390A
Research Areas:  

Metabolic Disease

GIP, rat TFA is a bioactive peptide derived from rats. GIP, rat TFA inhibits GIP-mediated postprandial insulin release as well as GIP-promoted glucose uptake in the upper small intestine. GIP, rat TFA can be used in research related to insulin resistance, glucose intolerance, and type 2 diabetes .
loading...
    loading...
Cat. No.: HY-139201E
CAS No.: 27964-99-4
Synonyms: PDLHB (MW 150000-300000)
Poly-D-lysine hydrobromide (MW 150000-300000) is a synthetic polymer composed of D-lysine residues and is one of the most widely used matrices in neural cell culture applications. Poly-D-lysine hydrobromide (MW 150000-300000) can be used as a non-specific cell adhesion enhancer. Poly-D-lysine hydrobromide (MW 30000-70000) is an orally active CaSR agonist peptide that indirectly activates the 5-HT₃ receptor signaling pathway, delaying gastric emptying and thereby slowing the rate at which glucose enters the small intestine and is absorbed .
loading...
    loading...
Cat. No.: HY-169784
CAS No.: 1436673-69-6
Target:  

Drug Derivative

Research Areas:  

Metabolic Disease

PPI-1040 is an orally bioavailable vinyl ether synthetic plasmalogen. PPI-1040 acts as a precursor of plasmalogen. PPI-1040 increases plasmalogen levels in plasmalogen-deficient mice and normalizes hyperactive behaviors in these mice. In wild-type mice, PPI-1040 retains the sn-1 vinyl ether group and sn-3 phosphoethanolamine group, and is converted into endogenous ethanolamine plasmalogen. PPI-1040 can be used in studies related to rhizomelic chondrodysplasia punctata .
loading...
    loading...
Cat. No.: HY-154912A
Purity:  ≥98.0%
Target:  

Chloride Channel

Research Areas:  

Inflammation/Immunology

PAT1inh-B01 hydrocholide is a selective SLC26A6 inhibitor. PAT1inh-B01 hydrocholide inhibits PAT1 (a Cl -/HCO3 - exchanger)-mediated anion exchange (IC50: 350 nM). PAT1inh-B01 hydrocholide blocks fluid absorption in small intestine. PAT1inh-B01 hydrocholide can be used for research of small intestinal hyposecretory disorders .
loading...
    loading...
Cat. No.: HY-111956
CAS No.: 375822-19-8
Target:  

Fluorescent Dye

Research Areas:  

Cancer

D-Ala-Lys-AMCA is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. D-Ala-Lys-AMCA can be used for characterizing PEPT1-specific substrates or inhibitors (Ex/Em = 390/480 nm) .
loading...
    loading...
Cat. No.: HY-B1278S1
CAS No.: 143731-16-2
α-Tocopherol-d6 (acetate) is the deuterium labeled D-α-Tocopherol acetate. D-α-Tocopherol acetate (D-Vitamin E acetate) can be hydrolyzed to d-alpha-tocopherol (VE) and absorbed in the small intestine .
loading...
    loading...