10024 Results for "

standards

" in MedChemExpress (MCE) Product Catalog:
Products (10024)

10024 Results for "standards" in MCE Product Catalog:

558
Y-27632 dihydrochloride (Standard)
Y-27632 dihydrochloride (Standard)
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558 Publications Verification
Art. -Nr.: HY-10583R
CAS. Nr.: 129830-38-2
Target:  

ROCK Organoid Reference Standards

Forschungsgebiete:  

Cancer

Y-27632 dihydrochloride (Standard) is the analytical standard of Y-27632 dihydrochloride. Y-27632 dihydrochloride is an orally active and ATP-competitive ROCK (Rho-kinase) inhibitor (ROCK-I Ki=220 nM; ROCK-II Ki=300 nM). Y-27632 dihydrochloride shows antiepileptic effects .
360
Dexamethasone (Standard)
Dexamethasone (Standard)
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360 Cited Publications
Art. -Nr.: HY-14648R
CAS. Nr.: 50-02-2
Synonyms: Hexadecadrol(Standard); Prednisolone F (Standard)
Target:  

Reference Standards Exosomes Glucocorticoid Receptor SARS-CoV Autophagy Complement System Mitophagy Bacterial Antibiotic ADC Payloads

Forschungsgebiete:  

Infection Inflammation/Immunology Endocrinology Cancer

Dexamethasone (Standard) is the analytical standard of Dexamethasone. This product is intended for research and analytical applications. Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes. Dexamethasone is highly effective in the control of COVID-19 infection. Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses.
193
Chloroquine phosphate (Standard)
Chloroquine phosphate (Standard)
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193 Cited Publications
Art. -Nr.: HY-17589R
CAS. Nr.: 50-63-5
Target:  

Reference Standards Parasite Autophagy SARS-CoV Toll-like Receptor (TLR) HIV Antibiotic

Forschungsgebiete:  

Infection Inflammation/Immunology Cancer

Chloroquine (phosphate) (Standard) is the analytical standard of Chloroquine (phosphate). This product is intended for research and analytical applications. Chloroquine phosphate is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine phosphate is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine phosphate is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro (EC50=1.13 μM) .
139
Fulvestrant (Standard)
Fulvestrant (Standard)
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139 Cited Publications
Art. -Nr.: HY-13636R
CAS. Nr.: 129453-61-8
Reinheit:  99.71%
Synonyms: ICI 182780(Standard); ZD 9238(Standard); ZM 182780 (Standard)
Target:  

Reference Standards Estrogen Receptor/ERR Autophagy Apoptosis

Forschungsgebiete:  

Cancer

Fulvestrant (Standard) is the analytical standard of Fulvestrant. This product is intended for research and analytical applications. Fulvestrant (ICI 182780) is a pure antiestrogen and a potent estrogen receptor (ER) antagonist with an IC50 of 9.4 nM. Fulvestrant is also a GPR30 agonist. Fulvestrant effectively inhibits the growth of ER-positive MCF-7 cells with an IC50 of 0.29 nM. Fulvestrant also induces autophagy and has antitumor efficacy .
138
Melatonin (standard)
Melatonin (standard)
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138 Cited Publications
Art. -Nr.: HY-B0075R
CAS. Nr.: 73-31-4
Synonyms: N-Acetyl-5-methoxytryptamine (standard); Melatonin
Category:  

Natural Products Microorganisms Other disease Disease markers Endogenous metabolite

Target:  

Reference Standards Melatonin Receptor Autophagy Mitophagy Endogenous Metabolite Apoptosis

Melatonin (Standard) is the analytical standard of Melatonin. This product is intended for research and analytical applications. Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Melatonin plays a role in sleep and possesses important antioxidative and anti-inflammatory properties . Melatonin is a novel selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation . Melatonin attenuates palmitic acid-induced (HY-N0830) mouse granulosa cells apoptosis via endoplasmic reticulum stress .
130
Retinoic acid (Standard)
Retinoic acid (Standard)
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130 Cited Publications
Art. -Nr.: HY-14649R
CAS. Nr.: 302-79-4
Synonyms: Vitamin A acid (Standard); all-trans-Retinoic acid (Standard); ATRA (Standard)
Category:  

Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Cancer

Target:  

Reference Standards RAR/RXR PPAR Endogenous Metabolite Autophagy

Retinoic acid (Standard) is the analytical standard of Retinoic acid. This product is intended for research and analytical applications. Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha.
124
Estradiol (Standard)
Estradiol (Standard)
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124 Cited Publications
Art. -Nr.: HY-B0141R
CAS. Nr.: 50-28-2
Synonyms: β-Estradiol (Standard); E2 (Standard); 17β-Estradiol (Standard); 17β-Oestradiol (Standard)
Category:  

Sunscreen Disease markers Endocrine diseases Phenols Cosmetic Research Endogenous metabolite Disease Research Fields Cancer Steroids

Target:  

Reference Standards Estrogen Receptor/ERR Endogenous Metabolite Bacterial

Estradiol (Standard) is the analytical standard of Estradiol. This product is intended for research and analytical applications. Estradiol (β-Estradiol) is a steroid hormone and the major female sex hormone. Estradiol can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. Estradiol can be used for the research of cancers, neurodegenerative diseases and neural tissue engineering .
97
Palmitic acid (Standard)
Palmitic acid (Standard)
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97 Cited Publications
Art. -Nr.: HY-N0830R
CAS. Nr.: 57-10-3
Category:  

Cardiovascular Disease Natural Products Neurological Disease Plants Endogenous metabolite Biological Pesticide Research Agricultural Research Human Gut Microbiota Metabolites other families Microorganisms Animals Disease Research Fields Cancer

Target:  

Reference Standards HSP Endogenous Metabolite

Palmitic acid (Standard) is the analytical standard of Palmitic acid. This product is intended for research and analytical applications. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. PA can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells .
90
Luteolin (Standard)
Luteolin (Standard)
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90 Cited Publications
Art. -Nr.: HY-N0162R
CAS. Nr.: 491-70-3
Synonyms: Luteoline(Standard); Luteolol(Standard); Digitoflavone (Standard)
Category:  

Human Gut Microbiota Metabolites other families Flavonoids Phenols Plants Endogenous metabolite Disease Research Fields Inflammation/Immunology

Target:  

Reference Standards Keap1-Nrf2 Apoptosis Autophagy Endogenous Metabolite

Luteolin (Standard) is the analytical standard of Luteolin. This product is intended for research and analytical applications. Luteolin (Luteoline), a flavanoid compound, is a potent Nrf2 inhibitor. Luteolin has anti-inflammatory, anti-cancer properties, including the induction of apoptosis and cell cycle arrest, and the inhibition of metastasis and angiogenesis, in several cancer cell lines, including human non-small lung cancer cells .
90
Nicotinamide (Standard)
Nicotinamide (Standard)
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90 Cited Publications
Art. -Nr.: HY-B0150R
CAS. Nr.: 98-92-0
Synonyms: Niacinamide(Standard); Nicotinic acid amide (Standard)
Target:  

Reference Standards Endogenous Metabolite Sirtuin

Forschungsgebiete:  

Cancer

Nicotinamide (Standard) is the analytical standard of Nicotinamide. This product is intended for research and analytical applications. Nicotinamide is a form of vitamin B3 or niacin. Nicotinamide Hydrochloride inhibits SIRT2 activity (IC50: 2 μM). Nicotinamide also inhibits SIRT1. Nicotinamide increases cellular NAD+, ATP, ROS levels. Nicotinamide inhibits tumor growth and improves survival. Nicotinamide also has anti-HBV activity .
88
Genistein (Standard)
Genistein (Standard)
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88 Cited Publications
Art. -Nr.: HY-14596R
CAS. Nr.: 446-72-0
Reinheit:  99.31%
Synonyms: NPI 031L (Standard)
Category:  

Anti-aging Plants Endogenous metabolite Human Gut Microbiota Metabolites Flavonoids Leguminosae Glycine max (L.) merr Sunscreen Phenols Cosmetic Research Disease Research Fields Glycyrrhiza uralensis Fisch. Cancer

Target:  

Reference Standards EGFR Autophagy Apoptosis Endogenous Metabolite

Genistein (Standard) is the analytical standard of Genistein. This product is intended for research and analytical applications. Genistein, a soy isoflavone, is a multiple tyrosine kinases (e.g., EGFR) inhibitor which acts as a chemotherapeutic agent against different types of cancer, mainly by altering apoptosis, the cell cycle, and angiogenesis and inhibiting metastasis.
86
Hydrocortisone (Standard)
Hydrocortisone (Standard)
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86 Cited Publications
Art. -Nr.: HY-N0583R
CAS. Nr.: 50-23-7
Synonyms: Cortisol (Standard)
Category:  

Endogenous metabolite Disease Research Fields Endocrinology Cancer Steroids

Target:  

Reference Standards Glucocorticoid Receptor Endogenous Metabolite

Hydrocortisone (Standard) is the analytical standard of Hydrocortisone. This product is intended for research and analytical applications. Hydrocortisone (Cortisol) is a steroid hormone or glucocorticoid secreted by the adrenal cortex .
85
Panobinostat (Standard)
Panobinostat (Standard)
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85 Cited Publications
Art. -Nr.: HY-10224R
CAS. Nr.: 404950-80-7
Synonyms: LBH589 (Standard); NVP-LBH589 (Standard)
Target:  

Reference Standards HDAC Autophagy HIV Apoptosis

Forschungsgebiete:  

Infection Cancer

Panobinostat (Standard) (LBH589 (Standard)) is the analytical standard of Panobinostat (HY-10224). This product is intended for research and analytical applications. Panobinostat is a potent and orally active non-selective HDAC inhibitor, and has antineoplastic activities . Panobinostat induces HIV-1 virus production even at low concentration range 8-31 nM, stimulates HIV-1 expression in latently infected cells . Panobinostat induces cell apoptosis and autophagy. Panobinostat can be used for the study of refractory or relapsed multiple myeloma .
83
Simvastatin (Standard)
Simvastatin (Standard)
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83 Cited Publications
Art. -Nr.: HY-17502R
CAS. Nr.: 79902-63-9
Synonyms: MK 733 (Standard)
Target:  

Reference Standards HMG-CoA Reductase (HMGCR) Autophagy Mitophagy Apoptosis Ferroptosis

Forschungsgebiete:  

Cardiovascular Disease Cancer

Simvastatin (Standard) is the analytical standard of Simvastatin. This product is intended for research and analytical applications. Simvastatin (MK 733) is a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM.
81
Capsaicin (Standard)
Capsaicin (Standard)
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81 Cited Publications
Art. -Nr.: HY-10448R
CAS. Nr.: 404-86-4
Reinheit:  99.38%
Synonyms: (E)-Capsaicin (Standard)
Category:  

Capsicum annuum L. Phenols Plants Solanaceae Disease Research Fields Biological Pesticide Research Cancer Agricultural Research

Target:  

Reference Standards TRP Channel Autophagy Apoptosis Endogenous Metabolite

Capsaicin (Standard) is the analytical standard of Capsaicin. This product is intended for research and analytical applications. Capsaicin ((E)-Capsaicin), an active component of chili peppers, is a TRPV1 agonist. Capsaicin induces a nociceptive response by binding to its receptors. Capsaicin has analgesic effects on neurological disorders. Capsaicin has antioxidant, anti-inflammatory, anti-cancer effects .
78
Kaempferol (Standard)
Kaempferol (Standard)
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78 Cited Publications
Art. -Nr.: HY-14590R
CAS. Nr.: 520-18-3
Reinheit:  99.80%
Synonyms: Kempferol(Standard); Robigenin (Standard)
Category:  

Anti-aging Plants Endogenous metabolite Human Gut Microbiota Metabolites other families Flavonoids Sunscreen Phenols Cosmetic Research Disease Research Fields Cancer

Target:  

Reference Standards Estrogen Receptor/ERR Autophagy Mitophagy Apoptosis HIV Parasite Endogenous Metabolite

Kaempferol (Standard) is the analytical standard of Kaempferol. This product is intended for research and analytical applications. Kaempferol (Kempferol), a flavonoid found in many edible plants, inhibits estrogen receptor α expression in breast cancer cells and induces apoptosis in glioblastoma cells and lung cancer cells by activation of MEK-MAPK. Kaempferol can be uesd for the research of breast cancer .
74
Cholesterol (Standard)
Cholesterol (Standard)
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74 Cited Publications
Art. -Nr.: HY-N0322R
CAS. Nr.: 57-88-5
Category:  

Anti-aging Metabolic Disease Endogenous metabolite Disease Research Fields Cancer Steroids

Target:  

Liposome Reference Standards Estrogen Receptor/ERR Endogenous Metabolite Bacterial

Cholesterol (Standard) is the analytical standard of Cholesterol. This product is intended for research and analytical applications. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins . Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist .
72
Mifepristone (Standard)
Mifepristone (Standard)
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72 Cited Publications
Art. -Nr.: HY-13683R
CAS. Nr.: 84371-65-3
Reinheit:  98.49%
Synonyms: RU486 (Standard); RU 38486 (Standard)
Target:  

Reference Standards Progesterone Receptor Glucocorticoid Receptor NO Synthase Autophagy

Forschungsgebiete:  

Endocrinology Cancer

Mifepristone (Standard) is the analytical standard of Mifepristone. This product is intended for research and analytical applications. Mifepristone (RU486) is a progesterone receptor (PR) and glucocorticoid receptor (GR) antagonist with IC50s of 0.2 nM and 2.6 nM in in vitro assay .
70
Acetaminophen (Standard)
Acetaminophen (Standard)
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70 Cited Publications
Art. -Nr.: HY-66005R
CAS. Nr.: 103-90-2
Synonyms: Paracetamol (Standard); 4-Acetamidophenol (Standard); 4'-Hydroxyacetanilide (Standard)
Target:  

Reference Standards COX Histone Acetyltransferase Endogenous Metabolite Bacterial Parasite

Forschungsgebiete:  

Inflammation/Immunology Cancer

Acetaminophen (Standard) is the analytical standard of Acetaminophen. This product is intended for research and analytical applications. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent . Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor .
65
Corticosterone (Standard)
Corticosterone (Standard)
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65 Cited Publications
Art. -Nr.: HY-B1618R
CAS. Nr.: 50-22-6
Synonyms: 17-Deoxycortisol(Standard); 11β,21-Dihydroxyprogesterone(Standard); Kendall's compound B (Standard)
Category:  

Neurological Disease Endogenous metabolite Disease Research Fields Endocrinology Steroids

Target:  

Reference Standards Glucocorticoid Receptor Endogenous Metabolite iGluR

Corticosterone (Standard) is the analytical standard of Corticosterone. This product is intended for research and analytical applications. Corticosterone (17-Deoxycortisol) is an orally active and adrenal cortex-produced glucocorticoid, which plays an important role in regulating neuronal functions of the limbic system (including hippocampus, prefrontal cortex, and amygdala). Corticosterone increases the Rab-mediated AMPAR membrane traffic via SGK-induced phosphorylation of GDI. Corticosterone also interferes with the maturation of dendritic cells and shows a good immunosuppressive effect .
Assay Types