61278-30-6
61278-30-6
Chemical Structure
D-Saccharic acid 1,4-lactone hydrate
- CAS No.: 61278-30-6
- Formula:C6H10O8
- Molecular Weight:210.14
IUPAC Name: (S)-2-((2S,3R,4R)-3,4-dihydroxy-5-oxotetrahydrofuran-2-yl)-2-hydroxyacetic acid hydrate
InChIKey: NPFKVZHSFSFLPU-QGBSHYGGSA-N
SMILES: OC([C@H]([C@]1([H])[C@@H]([C@H](C(O1)=O)O)O)O)=O.O
Biological Activity: D-Saccharic acid 1,4-lactone hydrate is an orally active β-glucuronidase inhibitor (IC50=48.4 μM). D-Saccharic acid 1,4-lactone hydrate can be used as a standard agent compared with novel β-glucuronidase inhibitors. D-Saccharic acid 1,4-lactone hydrate possesses anticarcinogenic, detoxifying, and antioxidant properties[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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D-Saccharic acid 1,4-lactone hydrate | 99.96% | D-Saccharic acid 1,4-lactone hydrate is an orally active β-glucuronidase inhibitor (IC50=48.4 μM). D-Saccharic acid 1,4-lactone hydrate can be used as a standard agent compared with novel β-glucuronidase inhibitors. D-Saccharic acid 1,4-lactone hydrate possesses anticarcinogenic, detoxifying, and antioxidant properties. | ||||||||||||||||||||
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References
- [1]. Taha M, et al. Synthesis, β-glucuronidase inhibition and molecular docking studies of hybrid bisindole-thiosemicarbazides analogs. Bioorg Chem. 2016;68:56-63. [Content Brief]
- [2]. Bhattacharya S, et al. Prophylactic role of D-Saccharic acid-1,4-lactone in tertiary butyl hydroperoxide induced cytotoxicity and cell death of murine hepatocytes via mitochondria-dependent pathways. J Biochem Mol Toxicol. 2011;25(6):341-354. [Content Brief]
